Publikationen

Institut für Chemie und Biotechnologie

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mi-WELT - A science dialogue for biotechnology. Prag

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ICT Prague Press.

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Pharmacokinetics of systemic, regional and topical drugs for therapy of intraocular inflammation

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Ophthalmologe, 111(2): 121-7. Peer reviewed.

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Phytochemical analysis using HPTLC and modern LC for application in quality control and medicinal plants research - trends and tools

: Plenary Lecture PL3.

In: Phytochemical Society of Europe (Hg.). Phytochemistry in Medicine and Pharmacognosy. 2014 Phytochemical Society of Europe Conference. Piatra Neamt, RO: PSE, Leicester.

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Production of a heteromeric amino acid transporter with Pichia pastoris. Prag

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ICT Prague Press.

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Scale-up of adipose tissue-derived mesenchymal stem cell production in stirred single-use bioreactors under low-serum conditions

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Engineering in Life Sciences Peer reviewed.

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Single-use wave-mixed versus stirred bioreactors for insect-cell/BEVS-based protein expression at benchtop scale

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Engineering in Life Sciences, 14, (3). 264-271. Peer reviewed.

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Surface Chemistry at Swiss Universities of Applied Sciences

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Chimia, 68, 7/8. 560-562.

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Synthese chiraler Halomethane und Oxirane

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àjour, 14(1) 14-16.

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Synthesis of trans-A2B2- and trans-A2BC-Porphyrins with Polar 4′-(Dimethylamino)-tolan-4-yl Substituents, and a Screening Protocol for Vapor-Phase Deposition on Metal Surfaces

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European Journal of Organic Chemistry 2014, 26, 5705–5719. Peer reviewed.

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The use of skin models in drug development

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Advanced Drug Delivery Reviews, 69-70C 81-102. Peer reviewed.

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Time efficient way to calculate oxygen transfer areas and power input in cylindrical disposable shaken bioreactors

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Biotechnology Progress Peer reviewed.

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What are chiral molecules good for?

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In: Paul Scheier; Roland Wester (Hg.). Symposium on Atomic, Surface and Cluster Physics (SASP) 2014. Innsbruck: IUP.

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What Happens to the Vitamin E in a Vitamin-Stabilised HXLPE?

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In: Tribology in Total Hip and Knee Arthroplasty. (197-205). Berlin Heidelberg: Springer.

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Wave-Mixed and Orbitally Shaken Single-Use Photobioreactors for Diatom Algae Propagation

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Chemie Ingenieur Technik, 85, 1-2. 197-201.

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An Approach for Scale-Up of Geometrically Dissimilar Orbitally Shaken Single-Use Bioreactors

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Chemie Ingenieur Technik, 85, 1-2. 118-126. Peer reviewed.

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Arnica montana L. cell suspension culture as a biotechnological approach for the production of bioactive secondary metabolites

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Planta medica, 79, 13. PN105. Peer reviewed.

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Bioengineering Parameters for Single-Use Bioreactors: Overview and Evaluation of Suitable Methods

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Chemie Ingenieur Technik, 85 40-56.

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Biofilme in Trinkwasserinstallationen

: Quantifizierung von Biofilmen in Kunststoffrohren.

AQUA & GAS, 3. 54-59.

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BRIDGING THE DISCIPLINES

: CANCER DIAGNOSTICS & TREATMENT.

Pan European Networks, 07 240-241.

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Chiral Molecules in Molecular Spectroscopy, invited talk

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In: Leopoldina Symposium. Spectroscopy and Molecular Dynamics at the Limit. Zürich: ETH Zürich.

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Comparative studies of single-use stirred bioreactors by means of traditional methods, CFD and cultivation experiments

: Kongressvortrag.

In: ACHEMA. Kongress. (20.Juni.2013). Frankfurt: DECHEMA.

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Cultivation of CHO Suspension Cells and SEAP Expression in the Finesse Glass Bioreactor

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BioProcess International, 11 (7), 30.

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Culture collections in the study of microbial diversity, importance

: Enzyclopedia of Metagenomics.

Editor: Karen E. Nelson (J. Craig Venter Institute). SpringerReference: Springer.

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CyBy²: Clevere Handhabung strukturbasierter Datensätze

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transfer, 1. 3.

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Development of a high sensitivity label free waveguide interferometry instrument: A project of Creoptix GmbH with the Center for Biochemistry ZHAW as main research partner

: Poster.

In: ILMAC. Industriemesse für Prozess- und Labortechnologie. Basel: MCH Group.

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Development of the Travelling Wave Bioreactor - A Concept Study

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Chemie Ingenieur Technik, 85, 1-2. 136-143. Peer reviewed.

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Direct Determination of Absolute Molecular Stereochemistry in Gas Phase by Coulomb Explosion Imaging

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Science, 341 1096-1100. Peer reviewed.

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Drug discovery through a chemist’s eyes

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International Innovation Report, 18 103.

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Dynamic Single-Use Bioreactors Used in Modern Liter- and m3- Scale Biotechnological Processes: Engineering Characteristics and Scaling Up

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In: Eibl-Schindler, Regine; Eibl, Dieter (Hg.). Advances in Biochemical Engineering/Biotechnology Disposable Bioreactors II. Springer Berlin Heidelberg.

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Effect of plant growth regulators on growth patterns and physiological status of Hypericum calycinum shoot cultures

: Poster.

In: Kliment days, International Conference, Bioscience,. 20.11.2013 Sofia . Sofia: Book of Abstracts Vol IV.

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Energy-related Chemical Research at the Universities of Applied Sciences

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Chimia, 67 611-613.

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Enzymatic activity and physiological status affect essential oils and polyphenolics production in Artemisia alba tissue cultures

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Planta Med, 79, 13. Peer reviewed.

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Expertenbeitrag im Buch von Claudia Lietha

: Borreliose - und dennoch hab' ich tausend Träume.

Giessen: Brunnen Verlag .

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Flow cytometry for the development of biotechnological processes with microalgae

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Biotechnology Advances, 31:, 1. 2-16. Peer reviewed.

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Fluid Flow and Cell Proliferation of Mesenchymal Adipose-Derived Stem Cells in Small-Scale, Stirred, Single-Use Bioreactors

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Chemie Ingenieur Technik, 85, 1-2. 95-102. Peer reviewed.

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Highly oxygnated sesquiterpenes from the aerial parts of Artemisia alba Turra

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Planta Med, 79, 13. Peer reviewed.

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Host-Guest Interactions and Orientation of Dyes in the One-Dimensional Channels of Zeolite L

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Langmuir, 29 9188-9198. Peer reviewed.

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Hosting the plant cells in vitro: recent trends in bioreactors

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Applied Microbiology and Biotechnology, 97(9), 3787-3800. Peer reviewed.

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HPTLC method for phytochemical and radical scavenging profiles of Chilean "Maqui" berries (Aristotelia chilensis) at different ripening stages from cultivated accessions

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Planta Med, 79, 13. Peer reviewed.

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Impact of IGF-I release kinetics on bone healing: A preliminary study in sheep

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European Journal of Pharmaceutics and Biopharmaceutics, 85(1): 99 - 106. Peer reviewed.

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Interlaboratory Test for Detection of Cytotoxic Leachables arising from Single-Use Bags

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Chemie Ingenieur Technik, 85, 1-2. 26-28. Peer reviewed.

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Investigation of parity violation in nuclear spin-rotation interaction of fluorooxirane

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Molecular Physics, 111, 14-15. 2345-2362. Peer reviewed.

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Investigations on Mechanical Stress Caused to CHO Suspension Cells by Standard and Single-Use Pumps

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Chemie Ingenieur Technik, 85 144–152.

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Ion activities in mixed electrolytes for calibration of ion selective electrodes used in clinical chemistry

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Accredit. Qual. Assur., 18 469-479. Peer reviewed.

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Katalytische und enzymatische Trennung kleiner chiraler Moleküle

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àjour, 13(1) 13-15.

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Label free non-invasive imaging of topically applied actives in reconstructed human epidermis by confocal Raman spectroscopy

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Vibrational Spectroscopy, 68, 1. 29-33. Peer reviewed.

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Modern Approaches to Determining Quality Criteria in Coffee

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In: 2nd Annual World Congress of Food Science & Technology-2013. Stadt: Verlag.

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New HPLC - method to determine Frangulin A and B as well as Glucofrangulin A and B in Frangulae cortex

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Planta Med, 79, 13. Peer reviewed.

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New UHPLC - method to determine Aloin A and B in Aloe capensis

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Planta Med, 79, 13. Peer reviewed.

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Novel CHO Suspension Cell Cultivation: Studying Cellular Growth and SEAP Expression in the Finesse SmartGlass Bioreactor

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Genetic Engineering & Biotechnology News, 33 (14), 32-33.

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Optimization of in vitro culture system for biomass and polyphenolics production in Inula britannica and Sideritis scardica Sofia 2 cultivar

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Planta Med, 79, 13. Peer reviewed.

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Organic chemistry: the heart and soul of drug discovery

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International Innovation Report, 18 104-105.

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Phytochemical assessment of the effect of stimulated in vitro multiplication on the metabolic profile of in vitro cultured Hypericum richeri and Artemisia alba

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Planta Med, 79, 13. Peer reviewed.

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Plant and Animal Suspension Cell Cultures: Scale-up of Geometrically Dissimilar Orbitally Shaken Single-Use Bioreactor

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Genetic Engineering & Biotechnology News, 33, 21.

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Problembasiertes Chemie-Grundlagenpraktikum

: Verändertes Menschenbild als Ausgangspunkt zur Neugestaltung der Lehre.

In: Heinz Bachmann (Hg.). Hochschullehre variantenreich gestalten:. Ansätze, Methoden und Beispiele rund um Kompetenzorientierung. (160-174). Bern: HEP Verlag.

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Self-Absorption and Luminescence Quantum Yields of Dye-Zeolite L Composites

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Journal of Physical Chemistry C, 117 23034-23047. Peer reviewed.

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Single-use Pumpen in der Prozesstechnologie

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ChemieXtra, 10, 30-31.

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Single-Use Technologies for Biopharmaceutical Production: Report from the Working Group Bioprocess Technology – Upstream Processing

: Report from the Working Group Bioprocess Technology – Upstream Processing.

Chemie Ingenieur Technik, 85 23-25.

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Stereochemistry of LinB-catalyzed biotransformation of δ-HBCD to 1R,2R,5S,6R,9R,10S-pentabromocyclododecanol

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Chemosphere, 90, 6. 1911-1919. Peer reviewed.

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Tackling antibiotic resistance

: Invited lecture.

In: ILMAC Award 2013. Basel: 25. September.

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TEDD - innovation network for 3D cell cultivation. 3D cell culture for drug development

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Chimia, 67, 11. 822-824. Peer reviewed.

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The Bulgarian Swiss Joint Research Project PhytoBalk - an example of application of biotechnological methods for the conservation of valuable medicinal plants germplasm and region independent biotechnological production of plant derived pharmaceuticals

: Poster.

In: 2nd GRF One Health Summit. International Symposium. (17.-20. November 2013). Davos: Global Risk Forum Davos.

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The forensiX Evidence Collection Tube and Its Impact on DNA Preservation and Recovery

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BioMed Research International, 2013, 10.1155/2013/105797. Peer reviewed.

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The Mangosteen Fruit and their active xanthones - an actual literature survey and an outlook for application in cosmetics

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In: Kosmetik Jahrbuch. Augsburg: Verlag Robert Fischer (in press). Peer reviewed.

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Beitrag zur Charakterisierung und zum Einsatz des 50 L Single-Use Bioreactor (S.U.B.) in der biopharmazeutischen Industrie

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In: Sperling, Reinhard; Heiser, Martin (Hg.). 14. Köthener Rührer-Kolloquium (52-67). Köthen/Anhalt:

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Biogene Güter - Wer liefert was?

: Update der Güterflussanalyse von Biogenen Gütern in der Schweiz.

Aqua & Gas, 92, 10. 48-52.

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chemf: A purely functional chemistry toolkit

: doi:10.1186/1758-2946-4-38 Highly accessed.

Journal of Cheminformatics, 4 38. Peer reviewed.

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Chiral Molecules: Spectroscopy, Dynamics and Fundamental Laws

: eingeladener Vortrag.

In: . Symposium. (8.6.2012). Tokyo, Japan: Japanese Chemical Society and University of Tokyo.

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Conventions, Symbols, Quantities, Units and Constants for High-Resolution Molecular Spectroscopy

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In: Quack, Martin; Merkt, Frederik (Hg.). Handbook of High-Resolution Spectroscopy. Volume 1: Fundamentals and Theory (263-324). Oxford: John Wiley & Sons.

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Critical aspects of sample handling for direct nanoparticle analysis and analytical challenges using asymmetric field flow fractionation in a multi-detector approach

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Journal of Analytical Atomic Spectrometry , 27, 7. 1120-1130. Peer reviewed.

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CyBy 2 : A structure based data management tool for chemical and biological data

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Chimia, 66, 3. 132-134. Peer reviewed.

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Design, synthesis and biological testing of novel MMP-Inhibitors

: Poster presentation.

In: SCS Fall meeting 2012 ETHZ. Symposium. (13.09.2012). Zurich: Swiss Chemical Society.

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Eine handliche Zusammenstellung einiger Grössen, Einheiten und Symbole in der Physikalischen Chemie

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Bunsenmagazin, 14, 6. 242-245.

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Enhancing CyBy2: Visualization of Structure Activity Relationships of large Datasets

: Poster presentation.

In: SCS Fall meeting 2012 ETHZ. Symposium. (13.09.2012). Zurich: Swiss Chemical Society.

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Generation of an Antibody Toolbox to Characterize hERG

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Biochemical and Biophysical Research Communications Peer reviewed.

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Grafting of α-Tocopherol upon γ-Irradiation in UHMWPE Probed by Model Hydrocarbons

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Polymer Degradation and Stability, 97, 11. 2255–2261. Peer reviewed.

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High-Temperature Diels–Alder Reactions: Transfer from Batch to Continuous Mode

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Organic Process Research & Development, 16, 5. 1114–1120. Peer reviewed.

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Homogeneous Model Complexes for Supported Rhenia Metathesis Catalysts

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Organometallics, 31, 21. 7558 - 7565. Peer reviewed.

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How can we Measure the Freshness of Coffee?

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Chimia, 66, 7/8. 494. Peer reviewed.

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Intelligent nanofibres as basis for new filter materials

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In: Global Guide of the Filtration and Separation Industry. Global Guide 2012-2014. (181-187). D-63322 Rödermark: VDL-Verlag.

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Intelligente Nanofasern als Basis für neue Filtermaterialien

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In: Global Guide of the Filtration and Separation Industry. Global Guide 2012-2014. (239-245). D-63322 Rödermark: VDL-Verlag.

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Large-scale, insect-cell-based vaccine development

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BioProcess International, 10(4,Suppl.): 2-7.

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Method for preserving cell density and viability in two-phase, fed-batch CHO culture

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BioProcess International, 10 (4): 1 - 6. Peer reviewed.

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NIRS of Chocolate and its Chemometric Analysis

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New Food, 15(6) 21-28.

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Phenytoin reduces 5-aminolevulinic acid-induced protoporphyrin IX accumulation in malignant glioma cells

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Journal of Neuro-Oncology, 108(3): 443-50. Peer reviewed.

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Spectroscopy and Its Contribution to the Understanding of Fundamental Laws in Nature

: eingeladener Vortrag.

In: Chirality in Physics and Chemistry. . Summerschool. (15. - 17-8.2012). Budenheim, Germany: R. Berger, TU Darmstadt.

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Spectroscopy of Chiral Molecules

: Tagungsreferat.

In: XVIII Symposium on Atomic, Cluster and Surface Physics (SASP). Symposium. (22. - 27.1.2012). Alpe d'Huerz, France: M. Lewerenz, O. Dutuit, R. Marquardt.

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Structure based design and synthesis of novel MMP Inhibitors

: Poster presentation.

In: . Symposium. (26.08.2012). Vienna: 19th EuroQSAR.

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Synthese und medizinalchemische Optimierung von Tetrazyklinanaloga

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SVC A Jour, 1. 10-11.

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Synthese und Spektroskopie kleiner chiraler Moleküle

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Transfer - Newsletter für anwendungsorientierte Forschung und Dienstleistung ZHAW, 3-2012. 8.

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Use of a mixture of glucose and methanol as substrates for the production of recombinant trypsinogen in continuous cultures with Pichia pastoris Mut+

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Journal of Biotechnology, 157: 180 - 188. Peer reviewed.

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Where Does the Oxygen Go? kLa Measurement in Bioreactors.

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G.I.T. Laboratory Journal, 9-10 20-21.

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A Concise Summary of Quantities, Units and Symbols in Physical Chemistry

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Chemistry International, 33, 4.

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All You Probably Never Wanted to Know About Molecular Parity Violation

: Keynote.

In: eingeladener Vortrag. (10.5.2011). Southampton, GB: University of Southampton.

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An Introduction to the Validation and Qualification of Disposables Used in Biomanufacture - A User's Perspective

: Chapter 13.

In: Regine Eibl-Schindler; Dieter Eibl (Hg.). Single Use Technology in Biopharmaceutical Manufacture. (160 ff.). Hoboken (New Jersey): John Wiley & Sons, Inc..

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Automated Disposable Systems:Application reports

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Single-use technology in biopharmaceutical manufacture. New Jersey: John Wiley & Sons.