Health Research Hub
Zusammenarbeit und wissenschaftlicher Austausch sind der Schlüssel zu erfolgreicher Forschung.
Health Research Hub
- verbindet Forschungsgruppen innerhalb der ZHAW,
- fördert deren Zusammenarbeit
- und schafft ein Netzwerk rund um die gesundheitsbezogene Forschung.
Interdisziplinäre Projekte
Das Health Research Hub fördert die gesundheitsbezogene Forschung und unterstützt interdisziplinäre Kooperationsprojekte. Die institutsübergreifende Bündelung der Kräfte fördert das Denken über Grenzen hinweg und bringt innovative gesundheitsbezogene Forschung voran.
Bayes network analysis for data-driven decision support in healthcare
Constantly rising costs in the healthcare sector require economic action without compromising the quality of care. In this project, extensive data collected from various hospitals is examined. The resulting models in the form of Bayesian networks will allow conclusions about hidden relationships and contribute to productivity and sustainability in health institutions.
Computational literature-based natural product drug discovery
Literature Based Discovery (LBD) has become widespread, but little has been done to automate it in the field of Natural Product Drug Discovery. The goal of this project is to devise an automated LBD system for natural product drugs for new discoveries, but also to query and explore present knowledge.
Engineered bacteriophages for the control of E. coli O157
Bacteriophages are bacterial viruses that are attracting increasing attention worldwide as a promising alternative to conventional antibiotics. The goal of this project is to genetically engineer bacteriophages for a better control of pathogenic Escherichia coli (E. coli) and to further develop large-scale phage production technologies.
Fighting bites with bytes - promoting public health with crowdsourced tick prevention
Ticks are currently on the rise and transmit several infectious diseases. A team of ZHAW experts in geographical information systems, artificial intelligence, data science and in tick biology develop a spacio-temporal tick risk model to help reducing the risk of tick-borne diseases.
Molecular mechanism of bacteriophage tail spike proteins in bacterial infection
Dramatic worldwide increase in antibiotic resistance to human pathogens is of great concern. Bacteriophages selectively kill bacteria and present an alternative to antibiotics. An expert team at ZHAW investigates interactions between bacteriophages and bacteria on a molecular level.
Silent pathway awakening to discover novel antibacterial compounds from actinomycetes
Many disease-causing bacteria are currently developing antibiotic resistance. This is a serious threat to human health. New antibiotics are therefore urgently needed. A project team of ZHAW and ETH is taking up this challenge.
Strategies to reduce mycotoxins in grain side product streams enabling their reintroduction into the food value chain
Food safety has become a major challenge within crops in recent years: an estimated 25% of all global crops are affected by moulds. This project aims at developing solutions to reduce mycotoxins in grain through the application of functional microorganisms and / or tailored enzymes.
News
Aktuelle Projekte
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Strategien zur Reduktion von Mykotoxinen in Getreidenebenproduktströmen
Wheat is one of our key staple foods worldwide and offers high nutritional value, especially when consumed in the form of whole grain. Food safety has become a major challenge in crops in recent years: an estimated 25% of all global crops are affected by moulds1-2. Certain moulds produce mycotoxins, toxic compounds ...
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ChitinOMix – A multidisciplinary project to understand the effect of chitin soil amendment on the plant response, natural microbial community and the fate of human pathogenic bacteria
Der Verzehr von Obst und Gemüse wird als wichtig für eine gesunde und ausgewogene Ernährung angesehen und als eine bedeutende Vitamin- und Ballaststoffquelle anerkannt. Die Behörden fördern den Konsum frischer Pflanzenprodukte, jedoch ist die Lebensmittelsicherheit von frischem Obst und Gemüse nach wie vor ein ...
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Computational literature-based natural product drug discovery
Natural products such as medicinal plants and extract mixtures have successfully supported the discovery of pharmaceuticals. Medically relevant products and their properties are often found through systematic analysis of the literature. In 1980s Swanson found hidden links between pieces of knowledge in the ...
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Induktion der Wirkstoffbildung bei Actinomyceten
Actinomyceten sind eine vielversprechende Quelle für die Gewinnung bioaktiver Substanzen und rücken für die Bekämpfung multiresistenter Bakterien zunehmend in den Fokus. Die ZHAW-Stammsammlung umfasst mehr als 3000 Stämme von Streptomyceten und seltenen Actinomyceten. Echinomycin, welches Gram-positive Bakterien ...
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Engineered bacteriophages for the control of E. coli O157
Bacteriophages (phages) represent a very promising alternative to antibiotics to combat infections caused by Shiga Toxin producing E. coli O157. In this research project, two different O157-specific bacteriophages will be genetically engineered to effectively control E. coli O157. In addition, a scalable setup for ...
Aktuelle Publikationen
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Schmitter, Paul; Gatziu Grivas, Stella,
2023.
Die Messung des digitalen Reifegrads.
Clinicum.
2023(3), S. 58-59.
Verfügbar unter: https://doi.org/10.21256/zhaw-28509
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Stäheli, Luca; Schwab, Lisa; Kinner, Mathias; Müller, Nadina,
2023.
Design and functionality of a prototype for cold needle perforation of wheat.
Applied Sciences.
13(10), S. 6266.
Verfügbar unter: https://doi.org/10.3390/app13106266
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Hon, Peiyun; Ko, Karrie K.K.; Zhong, Jonathan C.W.; De, Partha P.; Smits, Theo H. M.; Low, Jiaming; Vasoo, Shawn; Tsui, Clement K.M.,
2023.
Microbiology Resource Announcements.
12(6), S. e00167-23.
Verfügbar unter: https://doi.org/10.1128/mra.00167-23
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Schmitter, Paul; Kirecci, Ilyas; Gatziu Grivas, Stella; Hanne, Thomas; Beck, Chantal,
2023.
Transformation Compass für nicht-medizinische Supportprozesse (DE).
ZHAW Zürcher Hochschule für Angewandte Wissenschaften.
Verfügbar unter: https://doi.org/10.21256/zhaw-27958
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Arend, Lavinia N.V.S.; Bergamo, Ricardo; Rocha, Fabiano B.; Bail, Larissa; Ito, Carmen; Baura, Valter A.; Balsanelli, Eduardo; Pothier, Joël F.; Rezzonico, Fabio; Pilonetto, Marcelo; Smits, Theo H.M.; Tuon, Felipe Francisco,
2023.
Dissemination of NDM-producing bacteria in Southern Brazil.
Diagnostic Microbiology and Infectious Disease.
106(2), S. 115930.
Verfügbar unter: https://doi.org/10.1016/j.diagmicrobio.2023.115930
Team
Der Health Research Hub wird von einem wissenschaftlichen Ausschuss geleitet und von einem Programm-Manager unterstützt:
Komitee
Programm-Manager
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