Projects
Institute for Chemistry and Biotechnology
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Aroma recovery from coffee roasting
Aroma recovery from coffee roasting.
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Microalgae for large-scale CO2 re-mediation: Integrated concepts
Conceptual evaluation of microalgae-based CO2-remediation strategies for a Swiss-based company on the engineering sector.
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Unleashing the hidden potential of the anaerobic fungi (Neocallimastigomycota)
The microorganisms thriving in the ruminant’s digestive tract deliver the metabolic potential for degrading recalcitrant lignocellulose-rich organic matter and rendering it digestible. Amongst the microbiota thriving in the rumen, anaerobic fungi (AF) with the unpronounceable name Neocallimastigomycota host a ...
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3D chemistry - platform and app for classroom use and teaching - digitalization
Three-dimensional imagination is highly relevant for understanding the fundamentals of chemistry at university level. Especially when drawing molecular structures, it is important that students are able to imagine molecules/salts with the right geometry, so that the correct functioning in ...
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Microalgae-Food: Enhanced cultivation strategies for microalgae in food applications
Operational support (equipment installation, training, process development) in the implementation of a microalgae food production facility in Switzerland.
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Platform Health
Researchers from the School of Life Sciences and Facility Management (LSFM) initiated a platform to promote interdisciplinary research in the field of health. The School of LSFM supports this initiative to increase visibility of all health-research related activities in teaching, R&D, continued education, and ...
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Transglutaminase crosslinking potential
Evaluation of the transglutaminase crosslinking potential of self-assembly peptides for bioink development
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Local bioColours
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Bioprinting of vascular structures
Bioprinting of vascular structures based on enzymatically crosslinked gelatin. Tests involved core-shell extrusion of tubular structures and postprinting xlinking using various transglutaminase preparations.
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BioCat Nutrient supplementation
Regular (approximately monthly, depending on requirements) preparation of two standardised nutrient supplements in the environmental biotechnology laboratories and their delivery to the Electrochaea pilot plant. There the supplements are used in the experimental reactor for biological methanisation (BioCat ...
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Biocatalytic oxidation processes with alpha-ketoglutarate dependent enzymes for sustainable chemical synthesis
Development of biocatalytic oxidation processes with alpha-ketoglutarate dependent enzymes for sustainable chemical synthesis.
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MOSTCH4: Mini Onsite System To valorize manure in methane
In the project MOSTCH4; Mini Onsite System To valorize manure in methane, a miniaturized fermentation system for farmyard manure and other agricultural residues is being developed in cooperation with SUPSI, the University of Applied Sciences for Technology and Architecture of Southern Switzerland and the company ...
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Intellishaker
Integrated Bioprocess Development Solutions for Shaken Cultures: Eurostars-Project: E!11795. The consortium will develop a unique product that offers a cultivation success quarantee for shake flask cultivation to the user. The System consists of an Internet knowledge database for parallel bioprocess development in ...
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Microbiome therapeutics
Development of a novel two-step process for the production of next Generation microbiome therapeutics. We will develop an innovative, two step production technology for consortia of strict anaerobic gut bacteria. This will be the first GMP grade, large scale production process in the gut microbiome field, resulting ...
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Novel Antimicrobials for Life-Threatening Infections
Deaths due to antimicrobial resistance are alarmingly high, novel therapies are urgently needed. Here, novel antifungal compounds are developed against life-threatening infections. The compounds will be developed to preclinical proof-of-concept in a collaborative medicinal chemistry program. ...
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Virus cell entry machinery: antiviral drug discovery
Development of small molecule inhibitors of the viral cell entry machinery.
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Optimizing Synthesis of Zeolites by means of Photon Density Wave Spectroscopy (PDWS)
In this project, photon density wave spectroscopy (PDWS) is used for the first time for the development and optimization of zeolite syntheses, where inline analysis was previously only possible to a very limited extent due to high pressures, high temperatures and high pH values.
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HYKOM – Combination of Hygienisation and Hydrolysis as Pretreatment steps for liquid Substrates prior to Anaerobic Digestion.
The HYKOM project demonstrates on a technical scale in the biogas plant of Klaus and Urs Wittwer the energetically and microbiologically optimized combination of hygienization, hydrolysis and anaerobic biogas production in the agricultural co-fermentation plant for liquid substrates. In a primary thermal treatment ...
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isi - BioCat - In Situ Immobilized Biocatalysts
This project aims at developing new strategies for the production of biocatalysts in the form of inclusion bodies with optimized physicochemical properties. Bioprocess layouts specifically designed for the enrichment and activity enhancement of recombinant enzymes in intracellular compartments and the associated ...
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Biocatalytic Production - Engineering of terpene cyclases for the production of R-alpha-Ionone