Intellishaker

At a glance

Project leader : Prof. Dr. Dieter Eibl, Dr. Gernot John
Deputy of project leader : Prof. Christoph Herwig, Rüdiger Maschke
Project team : Sandra Steiner
Project budget : CHF 246'000
Project status : completed
Funding partner : EU and other international programmes (Eurostars / Projekt Nr. E!11795), Federal government (Staatssekretariat für Bildung, Forschung und Innovation SBFI)
Project partner : PreSens Precision Sensing GmbH, Körber AG / Pharma

Description

Integrated Bioprocess Development Solutions for Shaken Cultures: Eurostars-Project: E!11795. The consortium will develop a unique product that offers a cultivation success quarantee for shake flask cultivation to the user. The System consists of an Internet knowledge database for parallel bioprocess development in Pharmaceutical and technical applications, and is combined with advanced sensor technology and automated data analysis Software for cultivation monitoring. The product will complement existing flask Shakers, is flexible, scalable and connected using wireless Technology.

Publications

Maschke, Rüdiger; John, Gernot T.; Eibl, Dieter,

2022.

Monitoring of oxygen, pH, CO2, and biomass in smart single‐use shake flasks.

Chemie Ingenieur Technik.

94(12), pp. 1995-2001.

Available from: https://doi.org/10.1002/cite.202200094
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Herwig, Christoph; Eibl, Dieter,

2022.

Improved time resolved KPI and strain characterization of multiple hosts in shake flasks using advanced online analytics and data science.

Bioengineering.

9(8), pp. 339.

Available from: https://doi.org/10.3390/bioengineering9080339
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Herwig, Christoph; Eibl, Dieter,

2022.

Automated cell line characterization in shake flasks for multiple organisms [poster].

In:

7th BioProScale Symposium, Berlin, Germany, 28-31 March 2022.
Pretzner, Barbara; Maschke, Rüdiger; Haiderer, Claudia; John, Gernot T.; Herwig, Christoph; Sykacek, Peter,

2021.

Predictive monitoring of shake flask cultures with online estimated growth models.

Bioengineering.

8(11), pp. 177.

Available from: https://doi.org/10.3390/bioengineering8110177
Maschke, Rüdiger; John, Gernot T.,

2020.

Using online biomass and OUR measurements to characterize microbials, plant and animal cells growth in shake flasks.

In:

PreSens Webinar, online, 24. März 2021.

Available from: https://www.youtube.com/watch?v=Cgx_jRI_0QA
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Eibl, Dieter,

2020.

Characterizing CHO cell lines with SFR vario : what online measured data can tell about your cell culture.

PreSens Publications.

Available from: https://www.presens.de/knowledge/publications/application-note/characterizing-cho-cell-lines-with-sfr-vario-1723
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot; Eibl, Dieter,

2020.

Interpreting SFR vario online data gathered in plant cell suspension culture : characterization of plant cell lines for successful production processes.

PreSens Publications.

Available from: https://www.presens.de/knowledge/publications/application-note/characterizing-plant-cell-suspension-culture-with-sfr-vario-1725

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