Xhortomics: Entwicklung von diagnostischen und epidemiologischen Hilfsmitteln für die Xanthomonas hortorum Spezies Gruppe basierend auf OMICs Technologien
Auf einen Blick
- Projektleiter/in : Dr. Theo Smits
- Co-Projektleiter/in : Dr. Joël Pothier
- Projektteam : Nay Dia
- Projektvolumen : CHF 273'576
- Projektstatus : abgeschlossen
- Drittmittelgeber : SNF (COST / Projekt Nr. 177064)
- Kontaktperson : Theo Smits
Beschreibung
Despite its recent re-emergence and increased prevalence in many countries, the research on Xanthomonas hortorum species-level clade members has been very limited until now. It is thus important to have an increased knowledge thereof to be able to react to its increasing occurrence. Therefore, the overall aim of the SNF funded project called XhortOMICs is to study the genomic diversity of the different pathovars within the X. hortorum species-level clade in order to design novel diagnostic methods and to study the molecular base of host-specificity of the individual pathovars. Genomic data of X. hortorum species-level clade members are largely unavailable, and this project aims at filling that substantial gap. By establishing the genome sequences of representative isolates from this clade, this project will also fill in an important information gap with insights on population ecology, virulence, genetics and evolution. This will also allow designing genomics informed assays for rapid, easy and in-field diagnostics in order to contribute to a prevention of further spreading/introduction of these pathogens. Additionally, this project will study host-specificity and pathogenicity factors by setting up plant assays for bacterial mutant phenotyping.
Weiterführende Informationen
Publikationen
-
Costa, Joana; Pothier, Joël F.; Boch, Jens; Stefani, Emilio; Koebnik, Ralf,
2022.
Integrating science on Xanthomonas and Xylella for integrated plant disease management.
Microorganisms.
11(1), S. 6.
Verfügbar unter: https://doi.org/10.3390/microorganisms11010006
-
Dia, Nay C.; Cottyn, Bart; Blom, Jochen; Smits, Theo H. M.; Pothier, Joël F.,
2022.
Frontiers in Agronomy.
4(898778).
Verfügbar unter: https://doi.org/10.3389/fagro.2022.898778
-
Dia, Nay C.; Morinière, Lucas; Cottyn, Bart; Bernal, Eduardo; Jacobs, Jonathan M.; Koebnik, Ralf; Osdaghi, Ebrahim; Potnis, Neha; Pothier, Joël F.,
2022.
Xanthomonas hortorum – beyond gardens : current taxonomy, genomics, and virulence repertoires.
Molecular Plant Pathology.
23(5), S. 597-621.
Verfügbar unter: https://doi.org/10.1111/mpp.13185
-
Hakalová, Eliška; Čechová, Jana; Tekielska, Dorota A.; Eichmeier, Ales; Pothier, Joël F.,
2022.
Frontiers in Microbiology.
13.
Verfügbar unter: https://doi.org/10.3389/fmicb.2022.1007988
-
Dia, Nay C.; Van Vaerenbergh, Johan; Van Malderghem, Cinzia; Blom, Jochen; Smits, Theo H. M.; Cottyn, Bart; Pothier, Joël F.,
2021.
Xanthomonas hydrangeae sp. nov., a novel plant pathogen isolated from Hydrangea arborescens.
International Journal of Systematic and Evolutionary Microbiology.
71(12).
Verfügbar unter: https://doi.org/10.1099/ijsem.0.005163
-
Costa, Joana; Pothier, Joël F.; Boch, Jens; Stefani, Emilio; Jacques, Marie-Agnès; Catara, Vittoria; Koebnik, Ralf,
2021.
Integrating science on Xanthomonadaceae for sustainable plant disease management in Europe.
Molecular Plant Pathology.
22(12), S. 1461-1463.
Verfügbar unter: https://doi.org/10.1111/mpp.13150
-
Cottyn, B.; De Paepe, B.; Dia, Nay; Van Malderghem, C.; Pothier, Joël; Van Vaerenbergh, J.,
2021.
New Disease Reports.
43(2), S. e12008.
Verfügbar unter: https://doi.org/10.1002/ndr2.12008
-
Catara, Vittoria; Cubero, Jaime; Pothier, Joël; Bosis, Eran; Bragard, Claude; Đermić, Edyta; Holeva, Maria C.; Jacques, Marie-Agnès; Petter, Francoise; Pruvost, Olivier; Robène, Isabelle; Studholme, David J.; Tavares, Fernando; Vicente, Joana G.; Koebnik, Ralf; Costa, Joana,
2021.
Trends in molecular diagnosis and diversity studies for phytosanitary regulated Xanthomonas.
Microorganisms.
9(4), S. 862.
Verfügbar unter: https://doi.org/10.3390/microorganisms9040862
-
Fernandes, Camila; Martins, Leonor; Teixeira, Miguel; Blom, Jochen; Pothier, Joël; Fonseca, Nuno A.; Tavares, Fernando,
2021.
Microorganisms.
9(3), S. 624.
Verfügbar unter: https://doi.org/10.3390/microorganisms9030624
-
Dia, Nay C.; Rezzonico, Fabio; Smits, Theo H. M.; Pothier, Joël F.,
2020.
Microbiology Resource Announcements.
9(41), S. e00828-20.
Verfügbar unter: https://doi.org/10.1128/MRA.00828-20
-
Martins, Leonor; Fernandes, Camila; Blom, Jochen; Dia, Nay C.; Pothier, Joël F.; Tavares, Fernando,
2020.
International Journal of Systematic and Evolutionary Microbiology.
70(12), S. 6024-6031.
Verfügbar unter: https://doi.org/10.1099/ijsem.0.004386
Open Data und Downloads
Open Data
- Complete or high-quality draft genome sequences of six Xanthomonas hortorum strains sequenced with short- and long-read technologies. Available at ENA.
- High-quality draft genome sequences of distinct Xanthomonas spp. isolated from a single walnut tree host
- Xanthomonas hortorum species level clade strains isolated from hydrangea