Prof. Dr. Beate Sick

Prof. Dr. Beate Sick
ZHAW
School of Engineering
Forschungsschwerpunkt Data Analysis and Statistics
Technikumstrasse 81
8400 Winterthur
Persönliches Profil
Tätigkeit an der ZHAW
Dozentin für statistische Datenanalyse & Projektleiterin
www.ebpi.uzh.ch/en/aboutus/departments/biostatistics/teambiostats/sick.html
Lehrtätigkeit in der Weiterbildung
Arbeits- und Forschungsschwerpunkte, Spezialkenntnisse
Ensemble Methoden für hochdimensionale Daten
Deep Learning
Experimentelles Design & Studiendesign
Biostatistik
Regressions- und Klassifikationsverfahren
Aus- und Fortbildung
2009: Certificate in Pharmaceutical Medicine, ECPM, Pharmazentrum Basel
2001: Dissertation, Institut für Physikalische Chemie, ETH Zürich
1999: NDK in angewandter Statistik, ETH Zürich
1996: Zweites Staatsexamen in Mathematik und Physik, Berlin
1994: Erstes Staatsexamen in Mathematik und Physik, Universität Heidelberg
1994: Diplom in Physik, Universität Heidelberg
Beruflicher Werdegang
Aug. 2009 - heute: Projektleiterin & Dozentin am IDP, Zürcher Hochschule für Angewandte Wissenschaften
Jan. 2006 - Jul. 2009: Projektleiterin & Wissenschaftliche Mitarbeiterin am IDP, ZHAW
Mai 2003 - Dez. 2005: Leiterin der Bioinformatik der DNA Array Facility, Uni Lausanne
Jan. 2002 - Feb. 2003: Statistikerin bei OncoScore, einer Basler Diagnostikfirma
Jan. 2001 - Nov. 2001: Postdoc, ETH Zürich
Projekte
Publikationen
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Herzog, Lisa; Kook, Lucas; Götschi, Andrea; Petermann, Katrin; Hänsel, Martin; Hamann, Janne; Dürr, Oliver; Wegener, Susanne; Sick, Beate,
2022.
Deep transformation models for functional outcome prediction after acute ischemic stroke.
Biometrical Journal.
Verfügbar unter: https://doi.org/10.1002/bimj.202100379
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Kook, Lucas; Herzog, Lisa; Hothorn, Torsten; Dürr, Oliver; Sick, Beate,
2022.
Deep and interpretable regression models for ordinal outcomes.
Pattern Recognition.
122(108263).
Verfügbar unter: https://doi.org/10.1016/j.patcog.2021.108263
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Howard, Brian E.; Sick, Beate; Heber, Steffen,
2009.
Unsupervised assessment of microarray data quality using a Gaussian mixture model.
BMC Bioinformatics.
10(191).
Verfügbar unter: https://doi.org/10.1186/1471-2105-10-191
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Steiner, Albert; Sick, Beate,
2008.
A new method for travel time estimation on long freeway sections.
European Journal of Transport and Infrastructure Research.
8(4), S. 333-354.
Verfügbar unter: https://doi.org/10.21256/zhaw-4908
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Runne, Heike; Régulier, Etienne; Kuhn, Alexandre; Zala, Diana; Gokce, Ozgun; Perrin, Valérie; Sick, Beate; Aebischer, Patrick; Déglon, Nicole; Luthi-Carter, Ruth,
2008.
Journal of Neuroscience.
28(39), S. 9723-9731.
Verfügbar unter: https://doi.org/10.1523/JNEUROSCI.3044-08.2008
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Heber, Steffen; Sick, Beate,
2006.
Quality assessment of affymetrix GeneChip data.
OMICS: A Journal of Integrative Biology.
10(3), S. 358-368.
Verfügbar unter: https://doi.org/10.1089/omi.2006.10.358
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Psarros, Michael; Heber, Steffen; Sick, Manuela; Thoppae, Gnanasekaran; Harshman, Keith; Sick, Beate,
2005.
RACE : remote analysis computation for gene expression data.
Nucleic Acids Research.
46(22), S. W638-W643.
Verfügbar unter: https://doi.org/10.1093/nar/gki490
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Prummer, Michael; Sick, Beate; Renn, Alois; Wild, Urs P.,
2004.
Multiparameter microscopy and spectroscopy for single-molecule analytics.
Analytical Chemistry.
76(6), S. 1633-1640.
Verfügbar unter: https://doi.org/10.1021/ac034976g
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Kastner, C.; Prummer, M.; Sick, Beate; Renn, A.; Wild, U.P.; Dimroth, P.,
2003.
The citrate carrier CitS probed by single-molecule fluorescence spectroscopy.
Biophysical Journal.
84(3), S. 1651-1659.
Verfügbar unter: https://doi.org/10.1016/S0006-3495(03)74974-1
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Prummer, Michael; Sick, Beate; Hecht, Bert; Wild, Urs P.,
2003.
Three-dimensional optical polarization tomography of single molecules.
The Journal of Chemical Physics.
118(21), S. 9824.
Verfügbar unter: https://doi.org/10.1063/1.1569848
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Sick, Beate; Hecht, B.; Wild, U.P.; Novotny, L.,
2001.
Probing confined fields with single molecules and vice versa.
Journal of Microscopy.
202(2), S. 365-373.
Verfügbar unter: https://doi.org/10.1046/j.1365-2818.2001.00795.x
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Sick, Beate; Hecht, B.; Novotny, L.,
2000.
Orientational imaging of single molecules by annular illumination.
Physical Review Letters.
85(21), S. 4482-4485.
Verfügbar unter: https://doi.org/10.1103/PhysRevLett.85.4482
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Hecht, Bert; Sick, Beate; Wild, Urs P.; Deckert, Volker; Zenobi, Renato; Martin, Olivier J. F.; Pohl, Dieter W.,
2000.
Scanning near-field optical microscopy with aperture probes : fundamentals and applications.
The Journal of Chemical Physics.
112(18), S. 7761.
Verfügbar unter: https://doi.org/10.1063/1.481382
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Prummer, Michael; Hübner, Christian G.; Sick, Beate; Hecht, Bert; Renn, Alois; Wild, Urs P.,
2000.
Single-molecule identification by spectrally and time-resolved fluorescence detection.
Analytical Chemistry.
72(3), S. 443-447.
Verfügbar unter: https://doi.org/10.1021/ac991116k
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Stadelmann, Thilo; Tolkachev, Vasily; Sick, Beate; Stampfli, Jan; Dürr, Oliver,
2019.
Beyond ImageNet : deep learning in industrial practice
.
In:
Braschler, Martin; Stadelmann, Thilo; Stockinger, Kurt, Hrsg.,
Applied data science : lessons learned for the data-driven business.
Cham:
Springer.
S. 205-232.
Verfügbar unter: https://doi.org/10.1007/978-3-030-11821-1_12
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Dürr, Oliver; Sick, Beate,
2016.
Single-cell phenotype classification using deep convolutional neural networks.
Journal of Biomolecular Screening.
21(9), S. 998-1003.
Verfügbar unter: https://doi.org/10.1177/1087057116631284
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Sick, Beate; Dürr, Oliver,
2013.
Winterthur:
ZHAW Zürcher Hochschule für Angewandte Wissenschaften.
ISBN 978-3-905745-71-9.
Verfügbar unter: https://doi.org/10.21256/zhaw-4774
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Mätzener, Heinrich; Gutzwiller, Johanna; Sick, Beate; Maier, Hans-Christof; Tomatis, Laura,
2012.
Klarinettenklang : Versuch einer physiologischen Analyse.
Dissonance.
2012(118), S. 43-51.
Verfügbar unter: http://www.dissonance.ch/upload/pdf/diss118_43_hsm_hma_klarinettenklang.pdf
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Perrin, Daniel; Wildi, Marc; Sick, Beate; Fürer, Mathias; Gantenbein, Thomas,
2011.
From walking to jumping : statistical modeling of writing processes [Paper].
In:
Proceedings of the JACET 50th commemorative international convention.
JACET 50th Commemorative International Convention, Fukuoka, Japan, 30 August - 2 September 2011.
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Howard, Brian; Sick, Beate; Heber, Steffen,
2009.
Practical quality assessment of microarray data by simulation of differential gene expression [Paper].
In:
Bioinformatics Research and Applications.
5th International Symposium on Bioinformatics Research and Applications (ISBRA), Fort Lauderdale, USA, 13-16 May 2009.
Springer.
S. 18-27.
Lecture Notes in Computer Science ; 5542.
Verfügbar unter: https://doi.org/10.1007/978-3-642-01551-9_3
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Steiner, Albert; Sick, Beate,
2008.
New methods for travel time estimation on freeway sections.
MOTION Working Papers Transportation Systems
; 1.
Winterthur:
ZHAW Zürcher Hochschule für Angewandte Wissenschaften.
Verfügbar unter: https://doi.org/10.21256/zhaw-117
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Howard, Brian E.; Sick, Beate; Perera, Imara; Im, Yang Ju; Winter-Sederoff, Heike; Heber, Steffen,
2007.
Quality assessment of Affymetrix GeneChip data using the EM algorithm and a naïve Bayes classifier [Paper].
In:
2007 IEEE 7th International Symposium on BioInformatics and BioEngineering.
7th International Conference on BioInformatics and BioEngineering, Boston, USA, 14-17 October 2007.
IEEE.
Verfügbar unter: https://doi.org/10.1109/BIBE.2007.4375557
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Heber, Steffen; Sick, Beate,
2006.
Automatic quality assessment of Affymetrix GeneChip data [Paper].
In:
Proceedings of the 44th annual Southeast regional conference.
44th ACM Southeast Regional Conference, Melbourne FL, USA, 10-12 March 2006.
ACM.
S. 411-416.
Verfügbar unter: https://doi.org/10.1145/1185448.1185540
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Fürer, Mathias; Gantenbein, Thomas; Perrin, Daniel; Sick, Beate; Wildi, Marc,
2012.
Modeling writing phases : interdisciplinary method building – an interim report.
In:
7. Tage der Schweizer Linguistik, Lugano, 13.-14. September 2012.
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Sick, Beate; Steiner, Albert,
2007.
Travel time estimation for long freeway sections.
In:
Swiss Statistics Meeting, Lucerne, 14 -16 November 2007.
Swiss Statistical Society (SSS).