REFRACT – Repeat protein Function, Refinement, Annotation and Classification of Topologies

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Projektleiter/in : Dr. Maria Anisimova, Prof. Silvio Tosatto
Projektteam : Matteo Delucchi
Projektstatus : laufend
Drittmittelgeber : EU und andere Internationale Programme (Horizon 2020 / Projekt Nr. 823886)
Projektpartner : European Molecular Biology Laboratory EMBL, French National Centre for Scientific Research CNRS, Johannes Gutenberg-Universität Mainz, Spanish National Research Council, Stockholm University, National University of Quilmes, National University of La Plata, Pontifical Catholic University of Peru, Cayetano Heredia University, Pontifical Catholic University of Chile, Centro de Ingeniería Genética y Biotecnología de Cuba, National Autonomous University of Mexico, University of Cauca, Centro De Investigacion Cientifica Caucaseco Ltda
Kontaktperson : Maria Anisimova

Beschreibung

REFRACT is an international consortium aiming to extend our knowledge on the mechanism of tandem repeat protein (TRP) function and evolution, establishing a common classification and best practices. Starting from available state of the art computational tools and databases, it aims to drive a new level of TRP characterization leveraging the complementary expertise of institutions in Europe and Latin America.

Weiterführende Informationen

https://refract-rise.eu/

Publikationen

Apsley, Abner T.; Domico, Emma R.; Verbiest, Max A.; Brogan, Carly A.; Buck, Evan R.; Burich, Andrew J.; Cardone, Kathleen M.; Stone, Wesley J.; Anisimova, Maria; Vandenbergh, David J.,

2023.

A novel hypervariable variable number tandem repeat in the dopamine transporter gene (SLC6A3).

Life Science Alliance.

6(4), S. e202201677.

Verfügbar unter: https://doi.org/10.26508/lsa.202201677
Verbiest, Max; Maksimov, Mikhail; Jin, Ye; Anisimova, Maria; Gymrek, Melissa; Bilgin Sonay, Tugce,

2022.

Mutation and selection processes regulating short tandem repeats give rise to genetic and phenotypic diversity across species.

Journal of Evolutionary Biology.

36(2), S. 321-336.

Verfügbar unter: https://doi.org/10.1111/jeb.14106
Delucchi, Matteo; Näf, Paulina; Bliven, Spencer; Anisimova, Maria,

2021.

TRAL 2.0 : tandem repeat detection with circular profile hidden Markov models and evolutionary aligner.

Frontiers in Bioinformatics.

1(691865).

Verfügbar unter: https://doi.org/10.3389/fbinf.2021.691865
Delucchi, Matteo,

2020.

A new census of protein tandem repeats and their relationship with intrinsic disorder room [Poster].

In:

SIB Days 2020, virtual conference, 8-10 June 2020.

ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

S. 407.

Verfügbar unter: https://doi.org/10.3390/genes11040407
Delucchi, Matteo; Schaper, Elke; Sachenkova, Oxana; Elofsson, Arne; Anisimova, Maria,

2020.

A new census of protein tandem repeats and their relationship with intrinsic disorder.

Genes.

11(4), S. 407.

Verfügbar unter: https://doi.org/10.3390/genes11040407

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