3Brain is the world's first company to design and produce high-resolution microelectrode arrays (HD-MEAs). Featuring thousands of 3D microelectrodes, these HD-MEA platforms offer unparalleled precision and outperform current market leaders. This cutting-edge technology is the result of 15 years of development and experience with CMOS-MEA chips, which set a new standard for studying electrophysiological activity in brain organoids, slices and tissues, as well as in retinal cultures, in vitro human-derived stem cells and cardiac tissues. Through innovation, 3Brain is committed to advancing research in neuroscience, ophthalmology and cardiology, as well as drug discovery.

3Brain’s HD-MEA technology opens up new possibilities in drug discovery by enabling functional imaging assays, the identification of network functional and dysfunctional states and the precise evaluation of pharmacological responses. The CMOS-MEA platform uses HD-MEA probes to gather high-resolution electrophysiological data from neurons, cardiac cells, brain organoids, and human-derived stem cells, and specialized software facilitates analyzing and exporting the results.

BioCAM X  and BioCAM DupleX are 3Brain’s latest high-resolution CMOS-MEA systems featuring integrated circuit computing performance and a durable and compact design. To unlock the full research potential of in vitro cultures, the system pairs with tailor-made HD-MEA probes made up of 4,096 microelectrodes, available in 2D and 3D shapes, and 16 stimulation sites. Dedicated BrainWave 4 software shows the data collected in real-time and can perform analyses like spike detection, raster plot, spike waveform extraction, local field potential detection and more. It also offers a myriad of tools to export your data into video color maps, Microsoft Excel spreadsheets and customized charts and graphs.