Prof. Dr. Dieter Eibl

ZHAW School of Life Sciences and Facility Management
Centre for Biochemical Engineering and Cell Cultivation Technique
Grüentalstrasse 14
8820 Wädenswil

+41 (0) 58 934 57 11
dieter.eibl@zhaw.ch

Membership of networks

Projects

Muscle generator – The key to unlock scalable and affordable cultivated meat production / Project co-leader / Project ongoing
Prozesstransfer einer Kultivierungsstrategie für eine CHO-Zelllinie in einem wellendurchmischten Bioreaktor / Deputy project leader / Project completed
Process development and biomass production of S. cerevisiae spiked with heavy water / Deputy project leader / Project completed
Evaluation of cell separation using the GEA kytero® Single Use Pharma Separator with disk stack technology / Deputy project leader / Project completed
CFD industrial scale protein extraction / Deputy project leader / Project completed
Intellishaker / Project leader / Project completed
Microbiome therapeutics / Project leader / Project completed
Biocatalytic Production - Engineering of terpene cyclases for the production of R-alpha-Ionone / Deputy project leader / Project completed

Publications

Articles in scientific journal, peer-reviewed

Seidel, Stefan; Mozaffari, Fruhar; Maschke, Rüdiger W.; Kraume, Matthias; Eibl-Schindler, Regine; Eibl, Dieter,

2023.

Automated shape and process parameter optimization for scaling up geometrically non-similar bioreactors.

Processes.

11(9), pp. 2703.

Available from: https://doi.org/10.3390/pr11092703
Seidel, Stefan; Maschke, Rüdiger; Mozaffari, Fruhar; Eibl-Schindler, Regine; Eibl, Dieter,

2023.

Improvement of HEK293 cell growth by adapting hydrodynamic stress and predicting cell aggregate size distribution.

Bioengineering.

10(4), pp. 478.

Available from: https://doi.org/10.3390/bioengineering10040478
Seidel, Stefan; Eibl-Schindler, Regine; Eibl, Dieter,

2022.

Laboratory-independent exploration of stirred bioreactors and their fluid dynamics.

Education for Chemical Engineers.

42, pp. 80-87.

Available from: https://doi.org/10.1016/j.ece.2022.10.001
Kaiser, Stephan C.; Decaria, Paula N.; Seidel, Stefan; Eibl, Dieter,

2022.

Scaling‐up of an insect cell‐based virus production process in a novel single‐use bioreactor with flexible agitation.

Chemie Ingenieur Technik.

94(12), pp. 1950-1961.

Available from: https://doi.org/10.1002/cite.202200103
Seidel, Stefan; Maschke, Rüdiger; Kraume, Matthias; Eibl-Schindler, Regine; Eibl, Dieter,

2022.

CFD modelling of a wave-mixed bioreactor with complex geometry and two degrees of freedom motion.

Frontiers in Chemical Engineering.

4(1021416).

Available from: https://doi.org/10.3389/fceng.2022.1021416
Müller, Jan; Ott, Vivian; Weiss, Noémi; Neubauer, Peter; Eibl, Dieter; Eibl, Regine,

2022.

Process intensification using a one‐step inoculum production and high‐seeded fed‐batch processes.

Chemie Ingenieur Technik.

94(12), pp. 1977-1984.

Available from: https://doi.org/10.1002/cite.202200097
Maschke, Rüdiger; John, Gernot T.; Eibl, Dieter,

2022.

Monitoring of oxygen, pH, CO2, and biomass in smart single‐use shake flasks.

Chemie Ingenieur Technik.

94(12), pp. 1995-2001.

Available from: https://doi.org/10.1002/cite.202200094
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Herwig, Christoph; Eibl, Dieter,

2022.

Improved time resolved KPI and strain characterization of multiple hosts in shake flasks using advanced online analytics and data science.

Bioengineering.

9(8), pp. 339.

Available from: https://doi.org/10.3390/bioengineering9080339
Maschke, Rüdiger W.; Seidel, Stefan; Bley, Thomas; Eibl, Regine; Eibl, Dieter,

2022.

Determination of culture design spaces in shaken disposable cultivation systems for CHO suspension cell cultures.

Biochemical Engineering Journal.

177, pp. 108224.

Available from: https://doi.org/10.1016/j.bej.2021.108224
Ott, Vivian; Müller, Jan; Schirmer, Cedric; Weiss, Noémi; Göhmann, Rüdiger; Biewald, Andreas; Michel, Andrej; Eibl, Dieter; Eibl-Schindler, Regine,

2022.

Qualification of a single‐use disk stack separator for cell separation in mammalian cell‐based antibody production.

Chemie Ingenieur Technik.

94(12), pp. 1936-1943.

Available from: https://doi.org/10.1002/cite.202200096
Müller, Jan; Ott, Vivian; Eibl, Dieter; Eibl-Schindler, Regine,

2022.

Seed train intensification using an ultra-high cell density cell banking process.

Processes.

10(5), pp. 911.

Available from: https://doi.org/10.3390/pr10050911
Schirmer, Cedric; Eibl-Schindler, Regine; Maschke, Rüdiger; Mozaffari, Fruhar; Junne, Stefan; Daumke, Ralph; Ottinger, Melanie; Göhmann, Rüdiger; Ott, Christian; Wenk, Irina; Kubischik, Jens; Eibl, Dieter,

2022.

Single‐use technology for the production of cellular agricultural products : where are we today?.

Chemie Ingenieur Technik.

94(12), pp. 2018-2025.

Available from: https://doi.org/10.1002/cite.202200092
Seidel, Stefan; Eibl, Dieter,

2021.

Influence of interfacial force models and population balance models on the kLa value in stirred bioreactors.

Processes.

9(7), pp. 1185.

Available from: https://doi.org/10.3390/pr9071185
Schirmer, Cedric; Maschke, Rüdiger; Pörtner, Ralf; Eibl, Dieter,

2021.

An overview of drive systems and sealing types in stirred bioreactors used in biotechnological processes.

Applied Microbiology and Biotechnology.

Available from: https://doi.org/10.1007/s00253-021-11180-7
Eibl, Regine; Senn, Yannick; Gubser, Géraldine; Jossen, Valentin; van den Bos, Christian; Eibl, Dieter,

2021.

Cellular agriculture : opportunities and challenges.

Annual Review of Food Science and Technology.

12, pp. 51-73.

Available from: https://doi.org/10.1146/annurev-food-063020-123940
Gubser, Geraldine; Vollenweider, Sabine; Eibl, Dieter; Eibl, Regine,

2021.

Food ingredients and food made with plant cell and tissue cultures : state‐of‐the art and future trends.

Engineering in Life Sciences.

21(3-4), pp. 87-98.

Available from: https://doi.org/10.1002/elsc.202000077
Eibl, Dieter; Sievers, Martin; Eibl, Regine; Bachmann, Martin; Walton, Senta; Keel, Nik; Richner, Gilles; Stübinger, Stefan; Hirsch, Sven; Yeretzian, Chahan; Opitz, Sebastian E.W.; Heldal, Trond; Adlhart, Christian,

2021.

Keeping SARS-CoV-2 out : vaccines, filters, and self-disinfecting textiles.

Chimia.

75(3), pp. 215-218.

Available from: https://doi.org/10.2533/chimia.2021.215
Seidel, Stefan; Maschke, Rüdiger; Werner, Sören; Jossen, Valentin; Eibl, Dieter,

2020.

Oxygen mass transfer in biopharmaceutical processes : numerical and experimental approaches .

Chemie Ingenieur Technik.

93(1-2).

Available from: https://doi.org/10.1002/cite.202000179
Möller, Johannes; Hernández Rodríguez, Tanja; Müller, Jan; Arndt, Lukas; Kuchemüller, Kim B.; Frahm, Björn; Eibl-Schindler, Regine; Eibl, Dieter; Pörtner, Ralf,

2019.

Model uncertainty-based evaluation of process strategies during scale-up of biopharmaceutical processes.

Computers & Chemical Engineering.

134, pp. 106693.

Available from: https://doi.org/10.1016/j.compchemeng.2019.106693
Jossen, Valentin; Eibl-Schindler, Regine; Kraume, Matthias; Eibl, Dieter,

2018.

Growth behavior of human adipose tissue-derived stromal/stem cells at small scale : numerical and experimental investigations.

Bioengineering.

5(4), pp. 106.

Available from: https://doi.org/10.3390/bioengineering5040106
Eibl-Schindler, Regine; Jossen, Valentin; Eibl, Dieter,

2018.

Einweg-Bioreaktoren : therapeutische Antikörper.

Chemie in unserer Zeit.

52(4), pp. 230-237.

Available from: https://doi.org/10.1002/ciuz.201800803
Jossen, Valentin; van den Bos, Christian; Eibl-Schindler, Regine; Eibl, Dieter,

2018.

Manufacturing human mesenchymal stem cells at clinical scale : process and regulatory challenges.

Applied Microbiology and Biotechnology.

102(9), pp. 3981-3994.

Available from: https://doi.org/10.1007/s00253-018-8912-x
Eibl-Schindler, Regine; Meier, Philipp; Stutz, Irène Kathrin; Schildberger, David; Hühn, Tilo; Eibl, Dieter,

2018.

Plant cell culture technology in the cosmetics and food industries : current state and future trends.

Applied Microbiology and Biotechnology.

102(20), pp. 8661-8675.

Available from: https://doi.org/10.1007/s00253-018-9279-8
Kaiser, Stephan C.; Werner, Sören; Jossen, Valentin; Blaschczok, Katharina; Eibl, Dieter,

2018.

Power input measurements in stirred bioreactors at laboratory scale.

Journal of Visualized Experiments.

(135), pp. e56078.

Available from: https://doi.org/10.3791/56078
Schirmer, Cedric; Blaschczok, Katharina; Husemann, Ute; Leupold, Marco; Zahnow, Christian; Rupprecht, Jens; Glöckler, Rainer; Greller, Gerhard; Pörtner, Ralf; Eibl-Schindler, Regine; Eibl, Dieter,

2017.

Standardized qualification of stirred bioreactors for microbial biopharmaceutical production processes.

Chemie Ingenieur Technik.

89(12).

Available from: https://doi.org/10.1002/cite.201700039
Kaiser, Stephan C.; Werner, Sören; Jossen, Valentin; Kraume, Matthias; Eibl, Dieter,

2017.

Development of a method for reliable power input measurements in conventional and single-use stirred bioreactors at laboratory scale.

Engineering in Life Sciences.

17(5), pp. 500-511.

Available from: https://doi.org/10.1002/elsc.201600096
Eibl, Dieter; Eibl-Schindler, Regine,

2017.

Flexible biomanufacturing for the production of biotherapeutics.

Pharmaceutical Biomanufacturing.

5(1).
Demuth, Caspar; Varonier, Joel; Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter,

2016.

Novel probes for pH and dissolved oxygen measurements in cultivations from millilitre to benchtop scale.

Applied Microbiology and Biotechnology.

100(9), pp. 3853-3863.

Available from: https://doi.org/10.1007/s00253-016-7412-0
Kaiser, Stephan; Kraume, Matthias; Eibl, Dieter,

2016.

Development of the travelling wave bioreactor. Part I : design studies based on numerical models.

Chemie Ingenieur Technik.

88(1-2), pp. 77-85.

Available from: https://doi.org/10.1002/cite.201500092
Kaiser, Stephan; Perepelitsa, Nadja; Kraume, Matthias; Eibl, Dieter,

2016.

Development of the travelling wave bioreactor. Part II : engineering characteristics and cultivation results.

Chemie Ingenieur Technik.

88(1-2), pp. 86-92.

Available from: https://doi.org/10.1002/cite.201500091
Fries, Tobias; Dittler, Ina; Blaschczok, Katharina; Löffelholz, Christian; Dornfeld, Wolfgang; Schöb, Reto; Drews, Anja; Eibl, Dieter,

2016.

Quantifizierung der hydrodynamischen Beanspruchung von Pumpen auf tierische Zellen mittels des nicht-biologischen Modellsystems Emulsion.

Chemie Ingenieur Technik.

88(1-2), pp. 177-182.

Available from: https://doi.org/10.1002/cite.201500126
Jossen, Valentin; Schirmer, Cedric; Mostafa Sindi, Dolman; Eibl-Schindler, Regine; Kraume, Matthias; Pörtner, Ralf; Eibl, Dieter,

2016.

Theoretical and practical issues that are relevant when scaling up hMSC microcarrier production processes.

Stem Cells International.

2016(4760414).

Available from: https://doi.org/10.1155/2016/4760414
Kaiser, Stephan; Perepelitsa, Nadja; Dittler, Ina; Eibl, Dieter,

2015.

Experiences with a benchtop-scale glass bioreactor : engineering data and cultivation results.

BioProcess International.

13(10), pp. 46-52.

Available from: http://www.bioprocessintl.com/upstream-processing/bioreactors/experiences-with-a-benchtop-scale-glass-bioreactor-engineering-data-and-cultivation-results/
Kaiser, Stephan C.; Blaschczok, Katharina; Eibl, Dieter,

2015.

Cultivation of CHO suspension cells and SEAP expression in the finesse glass bioreactor.

BioProcess International.

Available from: http://www.bioprocessintl.com/sponsored-content/cultivation-of-cho-suspension-cells-and-seap-expression-in-the-finesse-glass-bioreactor
Dittler, Ina; Dornfeld, Wolfgang; Schöb, Reto; Cocke, Jared; Rojahn, Jürgen; Kraume, Matthias; Eibl, Dieter,

2015.

A cost effective and reliable method to predict mechanical stress in single-use and standard pumps.

Journal of Visualized Experiments.

Available from: https://doi.org/10.3791/53052
Werner, Sören; Greulich, Judith; Geipel, Katja; Steingroewer, Juliane; Bley, Thomas; Eibl, Dieter,

2014.

Mass propagation of Helianthus annuus suspension cells in orbitally shaken bioreactors : improved growth rate in single-use bag bioreactors.

Engineering in Life Sciences.

14(6), pp. 676-684.

Available from: https://doi.org/10.1002/elsc.201400024
Klöckner, Wolf; Lattermann, Clemens; Pursche, Franz; Büchs, Jochen; Werner, Sören; Eibl, Dieter,

2014.

Time efficient way to calculate oxygen transfer areas and power input in cylindrical disposable shaken bioreactors.

Biotechnology Progress.

30(6), pp. 1441-1456.

Available from: https://doi.org/10.1002/btpr.1977
Imseng, Nicole; Steiger, Nina; Frasson, David; Sievers, Martin; Tappe, Alexander; Greller, Gerhard; Eibl, Dieter; Eibl-Schindler, Regine,

2014.

Single-use wave-mixed versus stirred bioreactors for insect-cell/BEVS-based protein expression at benchtop scale.

Engineering in Life Sciences.

14(3), pp. 264-271.

Available from: https://doi.org/10.1002/elsc.201300131
Dittler, Ina; Kaiser, Stephan; Blaschczok, Katharina; Löffelholz, Christian; Bösch, Pascal; Dornfeld, Wolfgang; Schöb, Reto; Rojahn, Jürgen; Kraume, Matthias; Eibl, Dieter,

2014.

A cost-effective and reliable method to predict mechanical stress in single-use and standard pumps.

Engineering in Life Sciences.

14(3), pp. 311-317.

Available from: https://doi.org/10.1002/elsc.201300068
Blaschczok, Katharina; Löffelholz, Christian; Eibl-Schindler, Regine; Eibl, Dieter,

2014.

Combining single-use stirred bioreactor with standard cross-flow technology in biphasic protein production processes at pilot scale.

Engineering in Life Sciences.

14(3), pp. 327-331.

Available from: https://doi.org/10.1002/elsc.201300069
Schirmaier, Carmen; Jossen, Valentin; Kaiser, Stephan C.; Jüngerkeks, Frank; Silke, Brill; Safavi-Nab, Agnieszka; Siehoff, Ann; van den Bos, Christian; Eibl, Dieter; Eibl-Schindler, Regine,

2014.

Scale-up of adipose tissue-derived mesenchymal stem cell production in stirred single-use bioreactors under low-serum conditions.

Engineering in Life Sciences.

14(3), pp. 292-303.

Available from: https://doi.org/10.1002/elsc.201300134
Werner, Sören; Kaiser, Stephan C.; Kraume, Matthias; Eibl, Dieter,

2014.

Computational fluid dynamics as a modern tool for engineering characterization of bioreactors.

Pharmaceutical Bioprocessing.

2(1), pp. 85-99.
Jossen, Valentin; Kaiser, Stephan C.; Schirmaier, Carmen; Hermann, Jacqueline; Tappe, Alexander; Eibl, Dieter; Siehoff, Ann; van den Bos, Christian; Eibl-Schindler, Regine,

2014.

Modification and qualification of a stirred single-use bioreactor for the improved expansion of human mesenchymal stem cells at benchtop scale.

Pharmaceutical Bioprocessing.

2(4), pp. 311-322.
Kaiser, Stephan; Blaschczok, Katharina; Eibl, Dieter,

2013.

Cultivation of CHO suspension cells and SEAP expression in the finesse glass bioreactor.

BioProcess International.

11(7).
Werner, Sören; Olownia, Johanna; Egger, Daniel; Eibl, Dieter,

2013.

An approach for scale-up of geometrically dissimilar orbitally shaken single-use bioreactors.

Chemie Ingenieur Technik.

85(1-2), pp. 118-126.

Available from: https://doi.org/10.1002/cite.201200153
Löffelholz, Christian; Husemann, Ute; Greller, Gerhard; Meusel, Wolfram; Kauling, Jörg; Ay, Peter; Kraume, Matthias; Eibl-Schindler, Regine; Eibl, Dieter,

2013.

Bioengineering parameters for single-use bioreactors : overview and evaluation of suitable methods.

Chemie Ingenieur Technik.

85(1-2), pp. 40-56.

Available from: https://doi.org/10.1002/cite.201200125
Kaiser, Stephan; Jossen, Valentin; Schirmaier, Carmen; Eibl, Dieter; Brill, Silke; van den Bos, Christian; Eibl-Schindler, Regine,

2013.

Fluid flow and cell proliferation of mesenchymal adipose-derived stem cells in small-scale, stirred, single-use bioreactors.

Chemie Ingenieur Technik.

85(1-2), pp. 95-102.

Available from: https://doi.org/10.1002/cite.201200180
Blaschczok, Katharina; Kaiser, Stephan C.; Löffelholz, Christian; Imseng, Nicole; Burkart, Jürg; Bösch, Pascal; Dornfeld, Wolfgang; Eibl-Schindler, Regine; Eibl, Dieter,

2013.

Investigations on mechanical stress caused to CHO suspension cells by standard and single-use pumps.

Chemie Ingenieur Technik.

85(1-2), pp. 144-152.

Available from: https://doi.org/10.1002/cite.201200135
Lehmann, Nicolai; Rischer, Heiko; Eibl, Dieter; Eibl-Schindler, Regine,

2013.

Wave-mixed and orbitally shaken single-use photobioreactors for diatom algae propagation.

Chemie Ingenieur Technik.

85(1-2), pp. 197-201.

Available from: https://doi.org/10.1002/cite.201200137
Kaiser, Stephan; Kraume, M.; Eibl, Dieter,

2013.

Development of the travelling wave bioreactor : a concept study.

Chemie Ingenieur Technik.

85(1-2), pp. 136-143.

Available from: https://doi.org/10.1002/cite.201200127
Bogli, Nicole C.; Ries, Christoph; Adams, Thorsten; Greller, Gerhard; Eibl, Dieter; Eibl-Schindler, Regine,

2012.

Large-scale, insect-cell-based vaccine development.

BioProcess International.

10(2).

Available from: http://www.bioprocessintl.com/upstream-processing/upstream-single-use-technologies/large-scale-insect-cellbased-vaccine-development-330217/?pageNum=3
Rothe, Sebastian; Ries, Christoph; Eibl, Dieter; Walsh, Kieron; Hohenauer, Wolfgang,

2012.

Method for preserving cell density and viability in two-phase, fed-batch CHO culture.

BioProcess International.

10(4).

Available from: http://www.bioprocessintl.com/wp-content/uploads/bpi-content/BPI_A_121004AR10_O_178001a.pdf
Kaiser, Stephan; Eibl-Schindler, Regine; Eibl, Dieter,

2011.

Engineering characteristics of a single-use stirred bioreactor at benchtop scale : the Mobius CellReady 3 L bioreactor as case study.

Engineering in Life Sciences.

11(4), pp. 359-368.

Available from: https://doi.org/10.1002/elsc.201000171
Werner, Sören; Eibl-Schindler, Regine; Lettenbauer, Christine; Röll, Marcel; Eibl, Dieter; De Jesus, Maria; Zhang, Xiaowei; Stettler, Matthieu; Tissot, Stephanie; Bürkie, Cedric; Broccard, Gilles; Kühner, Markus; Tanner, Rolf; Baldi, Lucia; Hacker, David; Wurm, Florian M.,

2010.

Innovative, non-stirred bioreactors in scales form milliliters up to 1000 L for suspension cultures of cells using disposable bags and containers - a Swiss contribution.

Chimia.

64(11), pp. 819-823.

Available from: https://doi.org/10.2533/chimia.2010.819
Kaiser, Stephan; Löffelholz, Christian; Werner, Sören; Eibl, Dieter,

2010.

Numerische Fluiddynamik in der Biotechnologie.

Nachrichten aus der Chemie.

58(9), pp. 897-899.

Available from: https://doi.org/10.1002/nadc.201075806
Eibl-Schindler, Regine; Kaiser, Stephan; Lombriser, Renate; Eibl, Dieter,

2010.

Disposabe bioreactors : the current state-of-the-art and recommended applications in biotechnology.

Applied Microbiology and Biotechnology.

86(1), pp. 41-49.

Available from: https://doi.org/10.1007/s00253-009-2422-9
Ries, Christoph; John, Gernot; John, Corinne; Eibl-Schindler, Regine; Eibl, Dieter,

2010.

A shaken disposable bioreaktor system for controlled insect cell cultivations at millilitre-scale.

Engineering in Life Sciences.

10(1), pp. 75-79.

Available from: https://doi.org/10.1002/elsc.200900040
Eibl-Schindler, Regine; Werner, Sören; Eibl, Dieter,

2009.

Disposable bioreactors for plant liquid cultures at litre-scale.

Engineering in Life Sciences.

9(3), pp. 156-164.

Available from: https://doi.org/10.1002/elsc.200800102
Eibl-Schindler, Regine; Eibl, Dieter,

2009.

Disposable bioreactors in cell culture-based upstream processing.

BioProcess International.

7(1), pp. 18-23.

Available from: http://www.bioprocessintl.com/upstream-processing/cell-culture-media/disposable-bioreactors-in-cell-culture-based-upstream-processing-184055/
Eibl-Schindler, Regine; Eibl, Dieter,

2007.

Design of bioreactors suitable for plant cell and tissue cultures.

Phytochemistry Reviews.

7(3), pp. 593-598.

Available from: https://doi.org/10.1007/s11101-007-9083-z

Books and monographs, peer-reviewed

Eibl-Schindler, Regine; Eibl, Dieter, eds.,

2019.

Single-use technology in biopharmaceutical manufacture.

2nd Edition.

Wiley.

ISBN 978-1-119-47783-9.

Available from: https://doi.org/10.1002/9781119477891
Eibl, Dieter; Eibl-Schindler, Regine, eds.,

2013.

Disposable bioreactors II.

Berlin:

Springer.

Advances in Biochemical Engineering/Biotechnology ; 138.

ISBN 978-3-642-45157-7.

Available from: https://doi.org/10.1007/978-3-642-45158-4
Eibl-Schindler, Regine; Eibl, Dieter, eds.,

2011.

Single-use technology in biopharmaceutical manufacture.

Hoboken:

Wiley.

ISBN 978-0-470-43351-5.

Available from: https://doi.org/10.1002/9780470909997
Eibl-Schindler, Regine; Eibl, Dieter, eds.,

2010.

Disposable bioreactors.

Berlin:

Springer.

Advances in Biochemical Engineering/Biotechnology.

ISBN 978-3-642-01871-8.

Available from: https://doi.org/10.1007/978-3-642-01872-5

Book parts, peer-reviewed

Müller, Jan; Teale, Misha; Steiner, Sandra; Junne, Stefan; Neubauer, Peter; Eibl, Dieter; Eibl-Schindler, Regine,

2021.

Intensified and continuous mAb production with single-use systems

.

In:

Pörtner, Ralf, ed.,

Cell Culture Engineering and Technology.

Cham:

Springer.

pp. 401-429.

Cell Engineering ; 10.

Available from: https://doi.org/10.1007/978-3-030-79871-0_13
Jossen, Valentin; Eibl, Dieter; Eibl, Regine,

2020.

Numerical methods for the design and description of in vitro expansion processes of human mesenchymal stem cells

.

In:

Digital Twins.

Berlin:

Springer.

pp. 185-228.

Advances in Biochemical Engineering / Biotechnology ; 177.

Available from: https://doi.org/10.1007/10_2020_147
Schirmer, Cedric; Müller, Jan; Steffen, Nina; Werner, Sören; Eibl-Schindler, Regine; Eibl, Dieter,

2020.

How to produce mAbs in a cube-shaped stirred single-use bioreactor at 200 L scale

.

In:

Pörtner, Ralf, ed.,

Animal cell biotechnology : methods and protocols.

New York:

Springer.

pp. 169-186.

Methods in Molecular Biology ; 2095.

Available from: https://doi.org/10.1007/978-1-0716-0191-4_10
Schirmer, Cedric; Rothe, Sebastian; Jenness, Ernest; Eibl, Dieter,

2019.

Systems for coupling and sampling

.

In:

Eibl, Regine; Eibl, Dieter, eds.,

Single-use technology in biopharmaceutical manufacture.

Hoboken:

Wiley.

pp. 53-68.

Available from: https://doi.org/10.1002/9781119477891.ch5
Werner, Sören; Maschke, Rüdiger W.; Eibl, Dieter; Eibl, Regine,

2018.

Bioreactor technology for sustainable production of plant cell-derived products

.

In:

Pavlov, Atanas; Bley, Thomas, eds.,

Bioprocessing of Plant In Vitro Systems.

Cham:

Springer.

pp. 413-432.

Reference Series in Phytochemistry.

Available from: https://doi.org/10.1007/978-3-319-54600-1_6
Schirmer, Cedric; Nussbaumer, Thomas; Schöb, Reto; Pörtner, Ralf; Eibl-Schindler, Regine; Eibl, Dieter,

2018.

Development, engineering and biological characterization of stirred tank bioreactors

.

In:

Yeh, Ming-Kung; Chen, Yuan-Chuan, eds.,

Biopharmaceuticals.

London:

IntechOpen.

pp. 87-107.

Available from: https://doi.org/10.5772/intechopen.79444
Jossen, Valentin; Eibl-Schindler, Regine; Pörtner, Ralf; Kraume, Matthias; Eibl, Dieter,

2017.

Stirred bioreactors : current state and developments, with special emphasis on biopharmaceutical production processes

.

In:

Current Developments in Biotechnology and Bioengineering.

Elsevier.

pp. 179-215.

Available from: https://doi.org/10.1016/B978-0-444-63663-8.00007-0
Löffelholz, Christian; Kaiser, Stephan C.; Kraume, Matthias; Eibl, Dieter; Eibl-Schindler, Regine,

2014.

Dynamic single-use bioreactors used in modern liter- and m3-scale biotechnological processes : engineering characteristics and scaling up

.

In:

Eibl, Dieter; Eibl-Schindler, Regine, eds.,

Disposable bioreactors II.

Berlin:

Springer.

pp. 1-41.

Advances in Biochemical Engineering/Biotechnology ; 138.

Available from: https://doi.org/10.1007/10_2013_187
Eibl-Schindler, Regine; Steiger, Nina; Wellnitz, Sabine; Vicente, Tiago; John, Corinne; Eibl, Dieter,

2014.

Fast single-use VLP vaccine productions based on insect cells and the baculovirus expression vector system : influenza as case study

.

In:

Eibl, Dieter; Eibl-Schindler, Regine, eds.,

Disposable bioreactors II.

Berlin:

Springer.

pp. 99-125.

Advances in Biochemical Engineering/Biotechnology ; 138.

Available from: https://doi.org/10.1007/10_2013_186
Werner, Sören; Kraume, Matthias; Eibl, Dieter,

2011.

Bag mixing system for single-use

.

In:

Eibl-Schindler, Regine; Eibl, Dieter, eds.,

Single-use technology in biopharmaceutical manufacture.

Hoboken:

Wiley.

pp. 21-32.

Available from: https://doi.org/10.1002/9780470909997.ch3
Eibl-Schindler, Regine; Löffelholz, Christian; Eibl, Dieter,

2011.

Single-use bioreactors : an overview

.

In:

Eibl-Schindler, Regine; Eibl, Dieter, eds.,

Single-use technology in biopharmaceutical manufacture.

Hoboken:

Wiley.

pp. 145-158.

Available from: https://doi.org/10.1002/9780470909997.ch4
Löffelholz, Christian; Kaiser, Stephan; Werner, Sören; Eibl, Dieter,

2011.

CFD as tool in order to characterize single-use bioreactors

.

In:

Eibl-Schindler, Regine; Eibl, Dieter, eds.,

Single-use technology in biopharmaceutical manufacture.

Hoboken:

Wiley.

pp. 263-280.

Available from: https://doi.org/10.1002/9780470909997.ch22
Eibl-Schindler, Regine; Werner, Sören; Eibl, Dieter,

2010.

Bag bioreactor based on wave-induced motion : characteristics and applications

.

In:

Eibl-Schindler, Regine; Eibl, Dieter, eds.,

Disposable Bioreactors.

Berlin:

Springer.

pp. 55-87.

Advances in Biochemical Engineering / Biotechnology ; 115.

Available from: https://doi.org/10.1007/10_2008_15
Eibl-Schindler, Regine; Eibl, Dieter,

2009.

Application of disposable bag-bioreactors in tissue engineering and for production of therapeutic agents

.

In:

Kasper, Cornelia; van Griensven, Martijn; Pörtner, Ralf, eds.,

Bioreactor systems for tissue engineering.

Berlin:

Springer.

pp. 183-207.

Advances in Biochemical Engineering/Biotechnology ; 112.

Available from: https://doi.org/10.1007/10_2008_23

Conference contributions, peer-reviewed

Schirmer, Cedric; Ott, Vivian; Müller, Jan; Göhmann, Rüdiger; Biewald, Andreas; Eibl-Schindler, Regine; Eibl, Dieter,

2022.

Qualification of a single-use disk stack separator for modern mAb upstream processing at pilot scale [poster].

In:

27th ESACT Meeting, Lisbon, Portugal, 26-29 June 2022.

ESACT, European Association for Animal Cell Technology.
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Herwig, Christoph; Eibl, Dieter,

2022.

Automated cell line characterization in shake flasks for multiple organisms [poster].

In:

7th BioProScale Symposium, Berlin, Germany, 28-31 March 2022.
Maschke, Rüdiger; Werner, Sören; Stalder, Mischa; Jossen, Valentin; Eibl, Dieter,

2016.

Nutzung von Sensor Spots zur Bestimmung der Gelöstsauerstoffkonzentration in Single-use Systemen im Labormassstab [poster].

In:

Institut für Bioprozess- und Analysenmesstechnik, ed.,

Tagungsband.

18. Heiligenstädter Kolloquium "Technische Systeme für die Lebenswissenschaft", Heilbad Heiligenstadt, 19.-21. September 2016.

Winterthur:

ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

Available from: https://doi.org/10.21256/zhaw-1152
Meister, Jolanda; Maschke, Rüdiger; Werner, Sören; Abellan, Eric; Stichling, Nicole; Egger, Daniel; Eibl, Dieter,

2016.

Cultivation of CHO Cells in Thomson Optimum Growth™ Shake Flasks and Scale-up [poster].

In:

Biotech 2016: Biopharmaceutical Manufacturing and Single-Use Technologies.

Wädenswil:

ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

Available from: https://doi.org/10.21256/zhaw-1151
Maschke, Rüdiger; Werner, Sören; Meister, Jolanda; Rohr, Adrian; Abellan, Eric; Eibl, Dieter; Bley, Thomas,

2016.

Engineering characterization of Thomson Optimum Growth™ shake flasks with optimized geometry [poster].

In:

DECHEMA Himmelfahrtstagung: New Frontiers for Biotech-Processes, Koblenz, Deutschland, 2.-4. Mai 2016.

ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

Available from: https://doi.org/10.21256/zhaw-1141

Other publications

Ott, Vivian; Müller, Jan; Eibl-Schindler, Regine; Eibl, Dieter; Schirmer, Cedric; Göhmann, Rüdiger; Biewald, Andreas,

2022.

A new single-use disk stack separator for pilot scale CHO cell-based antibody productions [poster].

In:

ECI: Single-Use Technologies V: Building The Future, Marseille, France, 20-23 March 2022.

Available from: https://dc.engconfintl.org/sut_v/11/
Seidel, Stefan; Werner, Sören; Eibl, Dieter,

2020.

CFD for stirred bioreactors : analysis of different multiphase models to determine oxygen mass transfer [poster].

In:

Special Issue : 10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020.

10. ProcessNet-Jahrestagung und 34. DECHEMA-Jahrestagung der Biotechnologen 2020 : Processes for Future, Web-Konferenz, 21.-24. September 2020.

Wiley.

pp. 1324.

Available from: https://doi.org/10.1002/cite.202055288
Bayer, Marcus; Castan, Andreas; Eibl, Regine; Eibl, Dieter; Eisenkrätzer, Detlef; Fritz, Christina; Glaser, Robert; Glenz, Martin; Greller, Gerhard; Hug, Michelle; Kleebank, Sebastian; Kampmann, Markus; Krättli, Martin; Manser, Britta; Matuszczyk, Jens; Ottinger, Melanie; Schleper, Stefan; Schreiber, Marko; Seidel, Stefan; Selzer, Sebastian; Tanner, Markus; Teale, Misha; Tiemann, Karin,

2020.

Technical state-of-the-art and risk analysis on single-use equipment in continuous processing steps.

Frankfurt am Main:

DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie e.V..

ISBN 978-3-89746-226-7.

Available from: https://doi.org/10.21256/zhaw-26357
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Eibl, Dieter,

2020.

Characterizing CHO cell lines with SFR vario : what online measured data can tell about your cell culture.

PreSens Publications.

Available from: https://www.presens.de/knowledge/publications/application-note/characterizing-cho-cell-lines-with-sfr-vario-1723
Schirmer, Cedric; Ott, Vivian; John, Gernot T.; Eibl, Dieter,

2020.

Integration of chemical-optical oxygen and pH sensors in existing control units : cultivation monitoring in a glass bioreactor system with subsequently integrated sensor spots.

PreSens Publications.

Available from: https://www.presens.de/knowledge/publications/application-note/integration-of-chemical-optical-oxygen-and-ph-sensors-in-existing-control-units-1692
Maschke, Rüdiger; Pretzner, Barbara; John, Gernot; Eibl, Dieter,

2020.

Interpreting SFR vario online data gathered in plant cell suspension culture : characterization of plant cell lines for successful production processes.

PreSens Publications.

Available from: https://www.presens.de/knowledge/publications/application-note/characterizing-plant-cell-suspension-culture-with-sfr-vario-1725
Schirmer, Cedric; Dreher, Thomas; Leupold, Marco; Glaser, Robert; Castan, Andreas; Brown, Jason; Eibl, Dieter; Glöckler, Rainer,

2019.

Recommendation for biological evaluation of bioreactor performance for microbial processes.

2. revised edition.

Frankfurt am Main:

DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie e.V..

ISBN 978-3-89746-222-9.

Available from: https://dechema.de/dechema_media/Downloads/Positionspapiere/SingleUse_Microbial_ezl+2Ed+Sept2019-p-20005491.pdf
Schirmer, Cedric; Nussbaumer, Thomas; Schöb, Reto; Pörtner, Ralf; Eibl, Dieter,

2019.

Development of an universally useable single-use bioreactor for the benchtop scale [poster].

In:

BioTech 2019 : Biopharmaceutical Manufacturing and Single-Use Technologies, Wädenswil, Switzerland, 2-4 July 2019.

ZHAW Zürcher Hochschule für Angewandte Wissenschaften.
Rossi, Lia; Schirmer, Cedric; Teale, Misha; Kurt, Fabienne; Rosenthal, Florian; Eibl, Dieter,

2019.

Proof of concept study for cultivation of strict anaerobes in a single-use wave-mixed bioreactor [poster].

In:

BioTech 2019 : Biopharmaceutical Manufacturing and Single-Use Technologies, Wädenswil, Switzerland, 2-4 July 2019.

ZHAW Zürcher Hochschule für Angewandte Wissenschaften.
Jossen, Valentin; Eberle, Sebastian; Muoio, Francesco; Panella, Stefano; Tallone, Tiziano; Moccetti, Tiziano; Lindner, Matias; Müller, Michele; Eibl, Dieter; Eibl-Schindler, Regine; et al.,

2019.

Serum-free hMSC expansion in stirred single-use cultivation systems [poster].

In:

BioTech 2019 : Biopharmaceutical Manufacturing and Single-Use Technologies, Wädenswil, Switzerland, 2-4 July 2019.
Schirmer, Cedric; Nussbaumer, Thomas; Schöb, Reto; Pörtner, Ralf; Eibl, Dieter,

2019.

A universal stirred bioreactor for the development of biotherapeutics [poster].

In:

DECHEMA Himmelfahrtstagung: Intensification and digitalisation for integral bioprocessing, Hamburg, Germany, 27-29 May 2019.

DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie.
van den Bos, Christian; Jossen, Valentin; Eibl, Dieter; Eibl-Schindler, Regine,

2019.

Advanced therapy medicinal products (ATMPs) & GMP : 10 years after.

Die Pharmazeutische Industrie : pharmind.

81(4), pp. 508-513.
Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter,

2019.

Single‐use bioreactors : an overview

.

In:

Single‐Use Technology in Biopharmaceutical Manufacture.

Wiley.

pp. 37-52.

Available from: https://doi.org/10.1002/9781119477891.ch4
Jossen, Valentin; Eibl-Schindler, Regine; Kraume, Matthias; Eibl, Dieter,

2018.

Growth behavior of human adipose tissue-derived stromal/stem cells in single-use spinner flasks : numerical and experimental investigations [poster].

In:

ECI: Single Use Technologies III: Scientific and Technological Advancements, Utah, USA, 23-26 September 2018.
Schildberger, David; Stutz, Irene; Weber, Carlo; Pedan, Vasilisa; Schlüter, Ansgar; Huber, Petra; Chatelain, Karin; Chetschik, Irene; Eibl, Dieter; Hühn, Tilo; Eibl-Schindler, Regine,

2018.

Cast off! Chocolate from cacao cell cultures [poster].

In:

New Harvest 2018 Conference, Cambridge, USA, 20-21 July 2018.
Schirmer, Cedric; Eibl, Dieter,

2017.

Rührwerk für moderne Bioreaktoren.

Transfer.

2017(2), pp. 4.

Available from: https://doi.org/10.21256/zhaw-19304
Eibl-Schindler, Regine; Eibl, Dieter,

2017.

Single-Use-Systeme in der biopharmazeutischen Produktion : Chancen und Herausforderungen.

Die Pharmazeutische Industrie : pharmind.

79, pp. 719-724.
von Blarer, Damian; Senn, Yannick; Kienle, Klaus; Schirmer, Cedric; Blaschczok, Katharina; Husemann, Ute; Greller, Gerhard; Leupold, Marco; Rupprecht, Jens; Glöckler, Rainer; Eibl, Dieter,

2016.

Biological bioreactor characterization by means of an Escherichia coli model process [poster].

In:

BioTech 2016, Wädenswil, Switzerland, 5-8 September 2016.
Jossen, Valentin; Schirmer, Cedric; Eibl-Schindler, Regine; Kraume, Matthias; Pörtner, Ralf; Eibl, Dieter,

2016.

Expansion of human adipose tissue-derived stromal/stem cells in a wave-mixed single-use bioreactor : a proof-of-concept [poster].

In:

BioTech 2016, Wädenswil, Switzerland, 5-8 September 2016.
Meister, Jolanda; Maschke, Rüdiger; Werner, Sören; Eibl, Dieter; John, Gernot T.,

2016.

How to efficiently shake viscous culture broths.

Genetic Engineering & Biotechnology News.

36(15).

Available from: https://www.genengnews.com/magazine-issues/how-to-efficiently-shake-viscous-culture-broths/
Jossen, Valentin; Eibl-Schindler, Regine; Kraume, Matthias; Pörtner, Ralf; Eibl, Dieter,

2016.

Impact of shear stress on cell growth and microcarrier-cell-agglomerate formation in microcarrier-based cultivations of adipose tissue-derived stromal/stem cells [poster].

In:

BioTech 2016, Wädenswil, Switzerland, 5-8 September 2016.
Jossen, Valentin; Schirmer, Cedric; Eibl-Schindler, Regine; Kraume, Matthias; Pörtner, Ralf; Eibl, Dieter,

2016.

How to successfully scale up a microcarrier based expansion process of human mesenchymal stem cells from adipose tissue [poster].

In:

4th BioProScale Symposium 2016, Berlin, Germany, 6-8 April 2016.
Eibl, Dieter,

2016.

Einwegsysteme : Stand der Technik und sich abzeichnende Entwicklungen.

GMP Journal.

38, pp. 11-12.
Jossen, Valentin; Eibl, Dieter,

2015.

Fluid flow modelling through a porous scaffold for the evaluation of co-culture model of human mesenchymal stromal cells and human dermal microvascular endothelial cells for bone tissue engineering [poster].

In:

24th European Society for Animal Cell Techonology (ESACT) Meeting, Barcelona, Spain, 31 May - 3 June 2015.
Jossen, Valentin; Schirmaier, Carmen; John, Gernot T.; Eibl, Dieter; Eibl-Schindler, Regine,

2015.

On-line-pH- und -DO-Messungen in Mikrocarrier-basierter hMSC Kultur.

BIOspektrum.

21(4), pp. 422-424.

Available from: https://doi.org/10.1007/s12268-015-0597-4
Eibl-Schindler, Regine; Eibl, Dieter,

2015.

Single-use (disposable) systems in biopharmaceutical processing : quo vadis?.

ACHEMA Trend Reports.

13.
Jossen, Valentin; Pörtner, Ralf; Kaiser, Stephan C.; Kraume, Matthias; Eibl, Dieter; Eibl-Schindler, Regine,

2014.

Mass production of mesenchymal stem cells — impact of bioreactor design and flow conditions on proliferation and differentiation

.

In:

Eberli, Daniel, ed.,

Cells and Biomaterials in Regenerative Medicine.

InTech.

pp. 119-172.

Tissue Engineering and Regenerative Medicine.

Available from: https://doi.org/10.5772/59385
Jossen, Valentin; Schirmaier, Carmen; John, Gernot; Siehoff, Ann; Eibl, Dieter; Eibl-Schindler, Regine,

2014.

Online pH and DO measurement in microcarrier-based hMSC cultivations performed in single-use spinner flask [poster].

In:

BioTech 2014, Wädenswil, Switzerland, 4-5 September 2014.
Jossen, Valentin; Ott, Anita; Kaiser, Stephan; Brill, Silke; Spicker, Sonja; Safavi-nab, Agnieszka; Jüngerkes, Frank; Siehoff, Ann; Rosenbaum, Claudia; Reinisch, Barbara; van den Bos, Christian; Eibl, Dieter; Eibl-Schindler, Regine; et al.,

2014.

Microcarrier-based expansion of adipose tissue and bone marrow derived human mesenchymal stem cells in therapeutically relevant doses [poster].

In:

4th Lugano Stem Cell Meeting, Lugano, Switzerland, 23-24 June 2014.
Olownia, Johanna; Werner, Sören; Eibl, Dieter,

2013.

Plant and animal suspension cell cultures : scale-up of geometrically dissimilar orbitally shaken single-use bioreactor.

Genetic Engineering & Biotechnology News.

33(21), pp. 38-39.

Available from: https://doi.org/10.1089/gen.33.21.17
Kaiser, Stephan; Blaschczok, Katharina; Eibl, Dieter,

2013.

Novel CHO suspension cell cultivation : studying cellular growth and SEAP expression in the Finesse SmartGlass Bioreactor.

Genetic Engineering & Biotechnology News.

33(14), pp. 32-33.

Available from: https://doi.org/10.1089/gen.33.14.17
Jossen, Valentin; Kaiser, Stephan; Schirmaier, Carmen; van den Bos, Christian; Eibl, Dieter; Eibl-Schindler, Regine,

2013.

Investigations of fluif flow and microcarrier suspension for hMSC expansion in single-use stirred bioreactors [poster].

In:

BioTech 2013, Wädenswil, Switzerland, 3-5 June 2013.
Backoff, Tobias; Malig, Jennifer; Sören, Werner; Eibl, Dieter; John, Gernot T.,

2013.

Where does the oxygen go? : kLa measurement in bioreactors.

G.I.T. Laboratory Journal.

9(10), pp. 20-21.

Available from: http://www.laboratory-journal.com/applications/biological-methods/where-does-oxygen-go
Kaiser, Stephan; Eibl, Dieter,

2013.

Single-use Pumpen in der Prozesstechnologie.

ChemieXtra.

2013(10), pp. 30-31.
Löffelholz, Christian; Kaiser, Stephan; Werner, Sören; Eibl, Dieter,

2012.

Beitrag zur Charakterisierung und zum Einsatz des 50 L Single-Use Bioreactor (S.U.B.) in der biopharmazeutischen Industrie [paper].

In:

Heiser, Martin; Sperling, Reinhard, eds.,

Vortragssammlung / 14. Köthener Rührer-Kolloquium 2011.

14. Köthener-Rührer-Kolloquium, Köthen, 16. Juni 2011.

pp. 52-67.
Eibl-Schindler, Regine; Eibl, Dieter,

2011.

Single-use cell culture systems arrive : tracking the evolution and development of an increasingly used technology.

Genetic Engineering & Biotechnology News.

31(17), pp. 59-61.

Available from: https://doi.org/10.1089/gen.31.17.15
Kaiser, Stephan; Löffelholz, Christian; Werner, Sören; Eibl, Dieter,

2011.

CFD for characterizing standard and single-use stirred cell culture bioreactors

.

In:

Minin, Igor V.; Minin, Oleg V., eds.,

Computational fluid dynamics : technologies and applications.

Rijeka, Croatia:

InTech.

pp. 97-122.

Available from: https://doi.org/10.5772/23496
Löffelholz, Christian; Werner, Sören; Eibl, Dieter; Ay, Peter,

2010.

Untersuchungen zum Strömungsverhalten des Einweg-Vibromix-Bioreaktors [paper].

In:

Egbers, Christoph; Leder, Alfred; Ruck, Bodo; Dopheide, Dietrich, eds.,

Proceedings der 18. GALA-Fachtagung "Lasermethoden in der Strömungsmesstechnik".

18. Fachtagung "Lasermethoden in der Strömungsmesstechnik", Cottbus, 7.-9. September 2010.

Deutsche Gesellschaft für Laser-Anemometrie GALA.

18.
Eibl, Regine; Eibl, Dieter; Pörtner, Ralf; Catapano, Gerardo; Czermak, Peter, eds.,

2009.

Cell and tissue reaction engineering.

Berlin:

Springer.

Principles and Practice.

ISBN 978-3-540-68175-5.

Available from: https://doi.org/10.1007/978-3-540-68182-3
Löffelholz, Christian; Werner, Sören; Eibl, Dieter,

2009.

Einsatz von Computational Fluid Dynamics.

Transfer.

2009(2), pp. 8.

Available from: https://doi.org/10.21256/zhaw-4286
Eibl-Schindler, Regine; Eibl, Dieter,

2007.

Disposable bioreactors for cell culture based-processing.

Achema Worldwide News.

2, pp. 8-10.
Eibl, Dieter; Eibl-Schindler, Regine,

2007.

Einwegbioreaktoren für Zellkulturen : Status quo und Trends.

Pharma-Tec.

4, pp. 14-15.
Eibl-Schindler, Regine; Eibl, Dieter,

2005.

Einwegkultivierungstechnologie für biotechnische Pharma-Produktionen.

BioWorld.

3.
Zuchuat, F.; Luisier, A.C.; Crelier, S.; Eibl, Dieter; Müller, J.,

2005.

Starterkulturen und Schutzhüllen für bioaktive Stoffe.

BioWorld.

4.
Eibl-Schindler, Regine; Rutschmann, K.; Lisica, Lidija; Eibl, Dieter,

2003.

Kostenreduktion bei der Säugerzellkultivierung durch Einwegbioreaktoren?.

BioWorld.

5, pp. 22-23.
Eibl-Schindler, Regine; Brändli, Johanna; Lettenbauer, C.; Eibl, Dieter,

2000.

Kultivierung pflanzlicher und animaler Zellkulturen.

BioWorld.

5, pp. 48-50.
Eibl-Schindler, Regine; Lettenbauer, C.; Eibl, Dieter; Röllin, Markus,

1999.

Experiences in the application of the wave bioreactor.

BioForum Europe.

3, pp. 110-112.
Eibl, Dieter,

1999.

Konstruktive und hygienetechnische Anforderungen an Anlagen der Lebensmittelindustrie und Biotechnologie.

Lebensmittel-Technologie.

32(9), pp. 266-268.
Eibl-Schindler, Regine; Hans, Daniel; Warlies, S.; Lettenbauer, C.; Eibl, Dieter,

1999.

Zellkulturtechnik : Einsatz eines Taumelreaktorsystems mit interner Beleuchtung.

BioWorld.

2, pp. 10-12.
Eibl, Dieter; Jenny, D.; Meier, H.P.,

1996.

Einsatz eines Magnetrührwerkes in der Lebensmittel- und Pharmaindustrie.

BioWorld.

5, pp. 53-55.
Eibl, Dieter; Feller, H.; Kühne, B.,

1995.

CIP-Reinigung und Einsatz von Additiven in der Milchindustrie, Teil 1.

Lebensmittel-Technologie.

28(4), pp. 95-101.
Eibl, Dieter; Feller, H.; Kühne, B.,

1995.

CIP-Reinigung und Einsatz von Additiven in der Milchindustrie, Teil 2.

Lebensmittel-Technologie.

28(5), pp. 150-156.
Eibl, Dieter; Imhof, R.; Feller, H.; Kühne, B.,

1995.

CIP-Reinigung und Einsatz von Additiven in der Milchindustrie, Teil 3.

Lebensmittel-Technologie.

28(7-8), pp. 258-262.
Eibl, Dieter,

1993.

Biotechnologie in der Lebensmittelproduktion.

Lebensmittel-Technologie.

26(7-8), pp. 199-206.

Oral conference contributions and abstracts

Seidel, Stefan; Schirmer, Cedric; Eibl, Dieter,

2022.

Integration of a drive system based on magnetic levitation technology to power a stirred bioreactor.

In:

Levitronix Bioprocessing Conference, Boston, USA, 2 June 2022.

Available from: https://www.levitronix.com/app/uploads/2022/06/Stefan-2_1.mp4
Seidel, Stefan; Werner, Sören; Eibl, Dieter,

2020.

Analysis of different multiphase CFD models for aerated stirred bioreactors.

In:

8th OpenFOAM Conference, virtual, 13-15 October 2020.
Seidel, Stefan; Werner, Sören; Eibl, Dieter,

2020.

CFD for process engineering characterization.

In:

Levitronix Bioprocessing Conference, Webinar Part 3, 10 June 2020.
Maschke, Rüdiger; John, Gernot T.; Pretzner, Barbara; Eibl, Dieter,

2019.

Small scale bioprocess optimization using soft sensors.

In:

BioProcess International Europe, Vienna, Austria, 2-4 April 2019.

Available from: https://lifesciences.knect365.com/bpieurope/agenda/3#cell-culture-and-upstream-process-development_small-scale-bioprocess-optimization-using-soft-sensors
Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter,

2018.

Multiphase CFD simulations for supporting MC-based hMSC process development.

In:

5th BioProScale Symposium, Berlin, Germany, 20-22 March 2018.
Jossen, Valentin; Eibl-Schindler, Regine; Eibl, Dieter,

2017.

How to use Computational Fluid Dynamics in the development of cell therapeutics.

In:

ECI: Scale-up and Manufacturing of Cell-based Therapies V, San Diego, USA, 15-19 January 2017.
Maschke, Rüdiger; Stalder, Mischa; Werner, Sören; Abellan, Eric; Eibl, Dieter,

2017.

Multivariate process transfer and scale-up models for mammalian cell cultures.

In:

DECHEMA Himmelfahrtstagung: Models for Developing and Optimising Biotech Production, Neu-Ulm, Deutschland, 22. Mai 2017.
Jossen, Valentin; Eibl, Dieter,

2016.

Fluid flow simulations in a porous scaffold to improve co-cultivation of human mesenchymal stem cells and human microvascular endothelial cells for bone tissue engineering.

In:

BMT Dreiländertagung, Basel, Switzerland, 4-6 October 2016.
Maschke, Rüdiger; John, Gernot; Eibl, Dieter,

2016.

Potential von Sensor Spots für Single-Use Systeme im Labormassstab.

In:

18. Heiligenstädter Kolloquium "Technische Systeme für die Lebenswissenschaft", Heilbad Heiligenstadt, 19.-21. September 2016.
Schirmer, Cedric; Jossen, Valentin; Mostafa Sindi, Dolman; Eibl-Schindler, Regine; Böttcher, Lars; Eibl, Dieter,

2016.

Standardized expansion of human mesenchymal stem cells in wave-mixed single-use bioreactors.

In:

ILMAC, Basel, 2016.
Jossen, Valentin; Eibl, Dieter; Eibl-Schindler, Regine,

2015.

How can Computational Fluid Dynamics be used in order to rapidly expand bone marrow derived hMSCs in clinically relevant numbers.

In:

DECHEMA Himmelfahrtstagung, Hamburg, Germany, 11-13 May 2015.
Eibl-Schindler, Regine; Jossen, Valentin; Eibl, Dieter,

2015.

Mass production of hMSCs : an approach based on stirred single-use bioreactors.

In:

ECI: Scale-up and Manufacturing of Cell-based Therapies III, 18-22 January 2015.
Jossen, Valentin; Kaiser, Stephan; Siehoff, Ann; van den Bos, Christian; Eibl, Dieter; Eibl-Schindler, Regine,

2014.

A successful approach in order to rapidly scaling-up microcarrier-based expansion of human mesenchymal stem cells for allogeneic therapies.

In:

3rd International Conference on Tissue Science & Regenerative Medicine, Valencia, Spain, 24-26 September 2014.
Jossen, Valentin; Kaiser, Stephan; Eibl-Schindler, Regine; Eibl, Dieter,

2014.

Numerische Strömungsuntersuchungen für die Massstabsübertragung der Expansion von humanen mesenchymalen Stammzellen in gerührten Single-Use Bioreaktoren.

In:

17. Köthener-Rührer-Kolloquium, Köthen, Deutschland, 26. Juni 2014.
Jossen, Valentin; Kaiser, Stephan; Ott, Anita; Siehoff, Ann; Brill, Silke; Greller, Gerhard; Tappe, Alexander; Eibl-Schindler, Regine; Eibl, Dieter; et al.,

2014.

Optimization of a benchtop single-use bioreactor for the expansion of adipose-tissue and bone marrow derived human mesenchymal stem cells.

In:

41st Annual European Society for Artificial Organs Congress, Rome, Italy, 17-20 September 2014.
Löffelholz, Christian; Werner, Sören; Kaiser, Stephan; Husemann, Ute; Tappe, Alexander; Greller, Gerhard; Eibl, Dieter,

2013.

Comparative studies of single-use stirred bioreactors by means of traditional methods, CFD and cultivation experiments.

In:

ACHEMA Kongress, Frankfurt, Deutschland, 20. Juni 2013.
Löffelholz, Christian; Eibl, Dieter,

2011.

Characterization and scalability of the S.U.B. systems.

In:

Single-Use Technology Seminar - Thermo Fisher Scientific, Kopenhagen, Denmark, 26 Oktober 2011.

go back