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Prof. Dr. Sven Hirsch

Prof. Dr. Sven Hirsch

Prof. Dr. Sven Hirsch

ZHAW School of Life Sciences and Facility Management
Fachstelle Computational Health
Schloss 1
8820 Wädenswil

+41 (0) 58 934 54 44

Work at ZHAW

Management role

  • Head of Research/Focus Area, ZHAW digital health lab
  • Head, Center for Computational Health

Position at the ZHAW

Professor for computational health

Education and Continuing education

Expertise and research interests

Biomedical Modeling and Simulation, Digital Patient Twin, Digital Health

Medical imaging analysis & diagnostics systems, Modelling of biomedical processes, Data assimilation and machine intelligence, Sensor and time series analysis

multi-physics multi-scale continuum models in biomedical applications (CFD, structural mechanics, reaction models), system dynamics

model generation & aesthetics
Implications of digital media and technology on society

Chair for Sciences in the Board of Foundation Insel Hombroich

Professional milestones

2022 - Head of Center for Computational Health, Institute of Computational Life Sciences, ZHAW
2016 - Professor ZFH
2013 - 2021 Group Head Biomedical Simulation – Institute of applied simulation, ZHAW
2008 - 2013 Group Leader Biomedical Simulation – Computer vision lab (Prof. Székely), ETH Zürich
2008 - 2017 Head of Quantification, Senior Foresight Consultant, Z_punkt (
2007 - 2008 Project leader holographic topometry, ViRad Imaging/Uniklinik Düsseldorf/caesar Bonn
2004 - 2006 Assistent holographic facial topometry, Kantonspital Basel
2000 - artist (a.k.a Sven Mann) in media and sound art

Educational background

CAS Leadership & Governance for Higher Education (2023)
CAS didactics for higher education (2015)

PhD laser physics, Univ. Dusseldorf (2006)
Postgrad. Master Audiovisual Media (2002)
Diploma Physics, Univ. Heidelberg (1998) - Digital image processing and physiology

Membership of networks



Articles in scientific journal, peer-reviewed
Conference contributions, peer-reviewed
Other publications
Oral conference contributions and abstracts

Publications before appointment at the ZHAW

S Hirsch, P Burggraf, C Daheim. Scenario Planning with Integrated Quantification – Managing Uncertainty in Corporate Strategy Building. Foresight (2013)

S Hirsch, C Daheim. The meaning of clean electricity. Yearbook World Future Society (2012)

S Hirsch, P Burggraf. Quantifizierte Szenarien. Zukunftsmanager, online Publikation (2012)

S Hirsch, C Daheim. Zur Zukunft der Stromversorgung. Swissfuture (2011)

Christoph Russ, Simon Sündermann, Sven Hirsch, Volkmar Falk, Gabor Székely, Michael Gessat. On the Effect of Anatomy-based Multi-material Model Simulation of the Aortic Root. 4th International Workshop on Computational Phantoms for Radiation Protection, Imaging and Radiotherapy (2013)

Julien Egger, Ajit S. Mallik, Dominik Szczerba, Daniel A. Rüfenacht, Gabor Székely, Sven Hirsch. Spatial stabilization strategies applied to multiphysics modeling of blood clotting using a modified PTT model. International Conference on Computational Science, ICCS 2013 (2013)

Kulcsár Z, Augsburger L, Reymond P, Pereira VM, Hirsch S, Mallik AS, Millar J, Wetzel SG, Wanke I, Rüfenacht DA. Flow diversion treatment: intra-aneurismal blood flow velocity and WSS reduction are parameters to predict aneurysm thrombosis. Acta Neurochir (Wien) (2012)

Matthias Schneider, Johannes Reichold, Bruno Weber, Gábor Székely, Sven Hirsch. Tissue Metabolism Driven Arterial Tree Generation. Medical Image Analysis (2012)

Sven Hirsch, Johannes Reichold, Matthias Schneider, Gábor Székely, Bruno Weber. Topology and hemodynamics of the cortical cerebrovascular system. J Cereb Blood Flow Metab (2012)

S. Hirsch, B. Lloyd, D. Szczerba, G. Székely. A Multiscale Simulation Framework for Modeling Solid Tumor Growth with an Explicit Vessel Network. Multiscale Cancer Imaging, T. Deisboeck and G. Stamatsakos, Ed., Chapman & Hall /CRC (2010)

Matthias Schneider, Sven Hirsch, Gábor Székely, Bruno Weber, Bjoern H. Menze. Oblique Random Forests for 3-D Vessel Detection Using Steerable Filters and Orthogonal Subspace Filtering. MICCAI Workshop on Medical Computer Vision 2012 (2012)

Matthias Schneider, Sven Hirsch, Bruno Weber, Gábor Székely. Physiologically Based Construction of Optimized 3-D Arterial Tree Models. MICCAI 2011 (2011)

Bryn A. Lloyd, Sven Hirsch, Gabor Székely. Optimization of Case-specific Vascular Tree Models Based on Vessel Size Imaging. Proceedings of the 5th International Symposium on Biomedical Simulation - ISBMS10 (2010)

Sven Hirsch, Dominik Szczerba, Bryn Lloyd, Michael Bajka, Niels Kuster, Gabor Székely. A Mechano-Chemical Model of a Solid Tumor for Therapy Outcome Predictions. Computational Science - ICCS 2009 (2009)

F Prieels, S Hirsch, P Hering. Holographic topometry for a dense visualisation of soft tissue for facial reconstruction. Forensic Science, Medicine and Pathology (2009)

S Hirsch. Holographie als Messtechnik in der Medizin. Das holographische Wissen, Ed. Schröter und Rieger, diaphanes, Berlin, (2009)

A Thelen, S Frey, S Hirsch, P Hering. Improvements in shape-from-focus for holographic reconstructions with regard to focus operators, neighborhood-size, and height value interpolation. IEEE Trans Image Process, Vol.18, No.1 (2009)

S Hirsch. Digital and Analog Hologram Tomography for Medical Applications. Dissertation, Heinrich-Heine Universität Düsseldorf (2007)

S Hirsch et al. Single-Pulsed Digital Holographic Topometry Novel Optical Instrumentation for Biomedical Applications. Proc. SPIE Int. Soc. Opt. Eng. 6631, 66310I (2007)

S Hirsch et al. Ultrafast Holographic 3D Facial Topometry and Digital Reconstruction. In: Buzug et al. (Eds); Facial Reconstruction - Gesichtsrekonstruktion, BKA series: Police and Research 35 (2007)

S Heintz, S Hirsch, A Thelen, P Hering. Three-dimensional surface measurement using digital holography with pulsed lasers. Advances in Medical Engineering, Vol. 114, pp. 435-440 (2007)

S Frey, A Thelen, S Hirsch, P Hering. Generation of digital textured surface models from hologram recordings. Applied Optics, Vol. 46, No. 11, pp. 1986-1993 (2007)

R Bakanas, GA Gudaitis, SJ Zacharovas, DB Ratcliffe, S Hirsch, S Frey, A Thelen, N Ladriere, P Hering. Using a portable holographic camera in cosmetology. Journal of Optical Technology, Vol. 73, No. 7, pp. 457-461 (2006)

S Frey, A Thelen, S Hirsch, P Hering. Shape measurement using pulsed optical holography. Laser Technik Journal, No. 1, pp. 42-45 (2006)

K Schwenzer-Zimmerer, S Hirsch, T Seewald, P Hering. Holographic facial capturing for baby cleft patients. Journal of Cranio-Maxillofacial Surgery 34(1):119-119 (2006)

S Hirsch, et. al. Facial topometry using pulsed holography. In: Advances in Display Holography, Proceedings of the 7th International Symposium on Display Holography (2006)

N Ladriere, S Frey, A Thelen, S Hirsch, J Bongartz, D Giel, P Hering. Ultraschnelle holografische Gesichtsprofilvermessung mit vollautomatischer Hologrammentwicklung
Aktuelle Methoden der Laser-und Medizinphysik, 272-274 (2005)

S Frey, H Gill-Robinson, A Thelen, S Hirsch, N Ladriere, P Hering. Holographic surface imaging for archaeological applications, J. Biol. Res 80, 39-41 (2005)

M Hoch, S Mann. Fuzzy-Based Person Tracking in Real-Time. Computer Graphics International, 201-208 (2000)

D Uttenweiler, C Veigel, R Steubing, C Goetz, S Mann, H Haußecker, B Jaehne, & RHA Fink. Motion determination in actin filament !uorescence images with a spatio-temporal orientation analysis method. Biophys. J., 78: 2709-2715 (2000)

D Uttenweiler, C Veigel, R Steubing, C Goetz, S Mann, H Haußecker, B Jaehne, & RHA Fink. A spatio-temporal orientation method for analyzing actin filament sliding velocity in the in vitro motility assay. Biophys. J., 78(1):1474 (2000)

M Hoch, S Mann. Fuzzy-Based Person Tracking in Real-Time. Computer Graphics International, 201-208 (2000)

S Mann. Objektbasierte Bildfolgenanalyse zur Bewegungsbestimmung im in vitro Motility Assay unter Verwendung eines Strukturtensorverfahrens. Diplomarbeit (1998)