Prof. Dr. Martin Sievers

Projects

• Bestenförderung von Lernenden / Team member / Project completed
• Modulatoren der MMP-Hemopexin-Domäne / Project co-leader / Project completed
• Silent pathway awakening to discover novel antibacterial compounds from actinomycetes / Project leader / Project completed
• Plasmid-Toolbox for enzyme cascades / Deputy project leader / Project completed
• Identifizierung und Charakterisierung von Wirkstoffen aus Actinomyceten aus der Schweiz gegen pathogene Bakterien / Project leader / Project completed
• Kinetische Struktur-Aktivitäts-Beziehungen und röntgenkristallographische Bestimmung des Bindungsmodus von niedermolekularen Wirkstoffmolekülen / Project co-leader / Project completed
• Isolation, Identifikation und medizinalchemische Optimierung von biogenen Wirkstoffen / Project leader / Project completed
• Culture Collection of Switzerland / Project leader / Project completed

Publications

• Pothier, Joël F.; Bolt, Valentin; Arn, Fabienne; Frasson, David; Rhyner, Nicola; Sievers, Martin,

  2023.

  High-quality draft genome sequence of Streptomyces albidoflavus CCOS 2040, isolated from a Swiss soil sample.

  Microbiology Resource Announcements.

  12(3), pp. e01225-22.

  Available from: https://doi.org/10.1128/mra.01225-22

• Eibl, Dieter; Sievers, Martin; Eibl, Regine; Bachmann, Martin; Walton, Senta; Keel, Nik; Richner, Gilles; Stübinger, Stefan; Hirsch, Sven; Yeretzian, Chahan; Opitz, Sebastian E.W.; Heldal, Trond; Adlhart, Christian,

  2021.

  Keeping SARS-CoV-2 out : vaccines, filters, and self-disinfecting textiles.

  Chimia.

  75(3), pp. 215-218.

  Available from: https://doi.org/10.2533/chimia.2021.215

• Lindenmann, Urs; Brand, Michael; Gall, Flavio; Frasson, David; Hunziker, Lukas; Kroslakova, Ivana; Sievers, Martin; Riedl, Rainer,

  2020.

  Discovery of a class of potent and selective non‐competitive sentrin‐specific protease 1 inhibitors.

  ChemMedChem.

  15(8), pp. 675-679.

  Available from: https://doi.org/10.1002/cmdc.202000067

• Arn, Fabienne; Frasson, David; Kroslakova, Ivana; Rezzonico, Fabio; Pothier, Joël; Riedl, Rainer; Sievers, Martin,

  2020.

  Isolation and identification of actinomycetes strains from Switzerland and their biotechnological potential.

  Chimia.

  74(5), pp. 382-390.

  Available from: https://doi.org/10.2533/chimia.2020.382

• Peters, Christin; Frasson, David; Sievers, Martin; Buller, Rebecca,

  2019.

  Novel Old Yellow Enzyme subclasses.

  ChemBioChem.

  Available from: https://doi.org/10.1002/cbic.201800770

• Gall, Flavio; Hohl, Deborah; Frasson, David; Wermelinger, Tobias; Mittl, Peer R. E.; Sievers, Martin; Riedl, Rainer,

  2019.

  Drug design inspired by nature : crystallographic detection of an auto‐tailored protease inhibitor template.

  Angewandte Chemie: International Edition.

  58(12), pp. 4051-4055.

  Available from: https://doi.org/10.1002/anie.201812348

• Gall, Flavio; Hohl, Deborah; Frasson, David; Wermelinger, Tobias; Mittl, Peer R. E.; Sievers, Martin; Riedl, Rainer,

  2019.

  Von der Natur inspiriertes Wirkstoffdesign : kristallographische Detektion eines selbstgenerierten Inhibitor‐Grundgerüsts.

  Angewandte Chemie.

  131(12), pp. 4091-4096.

  Available from: https://doi.org/10.1002/ange.201812348

• Rutz, Dominik; Frasson, David; Sievers, Martin; Blom, Jochen; Rezzonico, Fabio; Pothier, Joël F.; Smits, Theo H.M.,

  2019.

  Comparative genomic analysis of the biotechnological potential of the novel species Pseudomonas wadenswilerensis CCOS 864T and Pseudomonas reidholzensis CCOS 865T.

  Diversity.

  2019(11), pp. 204.

  Available from: https://doi.org/10.3390/d11110204

• Rutz, Dominik; Frasson, David; Sievers, Martin; Blom, Jochen; Rezzonico, Fabio; Pothier, Joël F.; Smits, Theo H. M.,

  2019.

  High-quality draft genome sequence of Pseudomonas reidholzensis strain CCOS 865T.

  Microbiology Resource Announcements.

  8(3).

  Available from: https://doi.org/10.1128/MRA.01502-18

• Smits, Theo H.M.; Rezzonico, Fabio; Frasson, David; Vesga, Pilar; Vacheron, Jordan; Blom, Jochen; Pothier, Joël F.; Keel, Christoph; Maurhofer, Monika; Sievers, Martin,

  2019.

  Updated genome sequence and annotation for the full genome of Pseudomonas protegens CHA0.

  Microbiology Resource Announcements.

  8(39).

  Available from: https://doi.org/10.1128/MRA.01002-19

• Rutz, Dominik; Frasson, David; Sievers, Martin; Blom, Jochen; Rezzonico, Fabio; Pothier, Joël; Smits, Theo,

  2018.

  High-quality draft genome sequence of pseudomonas wadenswilerensis CCOS 864T.

  Microbiology Resource Announcements.

  7(16).

  Available from: https://doi.org/10.1128/MRA.01059-18

• Smits, Theo H. M.; Pothier, Joël F.; Ruinelli, Michela; Blom, Jochen; Frasson, David; Koechli, Chantal; Fabbri, Carlotta; Brandl, Helmut; Duffy, Brion; Sievers, Martin,

  2015.

  Complete genome sequence of the cyanogenic phosphate-solubilizing Pseudomonas sp. strain CCOS 191 : a close relative of Pseudomonas mosseli.

  Genome Announcements.

  3(3).

  Available from: https://doi.org/10.1128/genomeA.00616-15

• Frasson, David; Udovičić, Matije; Frey, Beat; Lapanje, Aleš; Zhang, De-Chao; Margesin, Rosa; Sievers, Martin,

  2015.

  Glaciimonas alpina sp. nov. isolated from alpine glaciers and reclassification of Glaciimonas immobilis Cr9-12 as the type strain of Glaciimonas alpina sp. nov..

  International Journal of Systematic and Evolutionary Microbiology.

  65, pp. 1779-1785.

  Available from: https://doi.org/10.1099/ijs.0.000174

• Imseng, Nicole; Steiger, Nina; Frasson, David; Sievers, Martin; Tappe, Alexander; Greller, Gerhard; Eibl, Dieter; Eibl-Schindler, Regine,

  2014.

  Single-use wave-mixed versus stirred bioreactors for insect-cell/BEVS-based protein expression at benchtop scale.

  Engineering in Life Sciences.

  14(3), pp. 264-271.

  Available from: https://doi.org/10.1002/elsc.201300131

• Hausammann, Georg J.; Heitkamp, Thomas; Matile, Hugues; Gsell, Bernard; Thoma, Ralf; Schmid, Georg; Frasson, David; Sievers, Martin; Hennig, Michael; Grütter, Markus G.,

  2013.

  Generation of an antibody toolbox to characterize hERG.

  Biochemical and Biophysical Research Communications.

  431(1), pp. 70-75.

  Available from: https://doi.org/10.1016/j.bbrc.2012.12.089

• Sievers, Martin; Dasen, Gottfried; Wermelinger, Tobias; Landert, Silvano; Frasson, David,

  2010.

  Culture Collections and the Biotechnology Deal.

  Chimia.

  64(11), pp. 782-783.

  Available from: https://doi.org/10.2533/chimia.2010.782

• Dobec, Marinko; Golubic, Dragutin; Punda-Polic, Volga; Kaeppeli, Franz; Sievers, Martin,

  2009.

  Rickettsia helvetica in dermacentor reticulatus ticks.

  Emerging Infectious Diseases.

  15(1), pp. 98-100.

  Available from: https://doi.org/10.3201/eid1501.080815

• Sievers, Martin; Uermösi, Christina; Fehlmann, Marc; Krieger, Sibylle,

  2003.

  Cloning, sequence analysis and expression of the F1F0- ATPase beta-subunit from wine lactic acid bacteria.

  Systematic and Applied Microbiology.

  26(3), pp. 350-356.

  Available from: https://doi.org/10.1078/072320203322497374

• Sievers, Martin,

  2013.

  Culture collections in the study of microbial diversity, importance

  .

  In:

  Nelson, Karen E., ed.,

  Encyclopedia of metagenomics.

  Springer.

  Available from: https://doi.org/10.1007/978-1-4614-6418-1_741-4

• Gall, Flavio; Riedl, Rainer; Sievers, Martin; Wermelinger, Tobias; Frasson, David,

  2019.

  Durch die Natur inspiriertes Wirkstoffdesign.

  Transfer.

  2019(1), pp. 6.

  Available from: https://doi.org/10.21256/zhaw-30046

• Gall, Flavio; Hohl, Deborah; Frasson, David; Wermelinger, Tobias; Mittl, Peer R. E.; Sievers, Martin; Riedl, Rainer,

  2019.

  Cover picture : drug design inspired by nature : crystallographic detection of an auto‐tailored protease inhibitor template (Angew. Chem. Int. Ed. 12/2019).

  Angewandte Chemie: International Edition.

  58(12), pp. 3653.

  Available from: https://doi.org/10.1002/anie.201901671

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