Dr. Christin Peters

Personal profile

Position at the ZHAW

Group leader Biosystems technology

www.zhaw.ch/de/lsfm/institute-zentren/icbt/biokatalyse-und-prozesstechnologie/biosystemtechnologie/

Educational background

1/2016-8/2018
Postdoc
Competence Center for Biocatalysis
ZHAW in Wädenswil, Switzerland

10/2012 - 10/2015
Ph. D. studies in Biochemistry
Institute of Biochemistry
Dept. of Biotechnology & Enzyme Catalysis
Ernst-Moritz-Arndt University of Greifswald, Germany
Supervisor Uwe T. Bornscheuer
Kopplung von Oxidoreduktasen in syntetischen Enzymkaskaden

9/2012
Biochemistry Diploma
Institute of Biochemistry
Dept. of Biotechnology & Enzyme Catalysis
Ernst-Moritz-Arndt University of Greifswald, Germany
Supervisor Uwe T. Bornscheuer
Untersuchungen zu Enoatreduktasen

10/2007 - 9/2012
Undergraduate and graduate studies of Biochemistry
Institute of Biochemistry
Ernst-Moritz-Arndt University of Greifswald, Germany

Projects

• Flow Chemistry für Enzymkaskaden / Project leader / Project ongoing
• Biocatalytic halogenation for the sustainable development of agrochemicals / Deputy project leader / Project ongoing
• NCCR Catalysis / Team member / Project ongoing
• Microbial Epimerases: A Toolbox for the Synthesis of Novel Peptide-Based Drugs / Deputy project leader / Project ongoing
• Die Exploration der Gen-Harmonisierung / Project leader / Project completed
• Impulse - Digitalization in biofabrication: Design, recombinant production and testing of innovative Protein scaffolds as inks for 3D bioprinting / Project leader / Project completed
• Plasmid-Toolbox für Enzymkaskaden / Project leader / Project completed
• CAS - Biocatalysis / Team member / Project completed
• Biocatalytic Production - Engineering of terpene cyclases for the production of R-alpha-Ionone / Team member / Project completed
• PgB P-14 Engineered Halogenases / Deputy project leader / Project completed
• simCAT – mobiles Hilfsmittel zur rekombinanten Enzymproduktion und Biokatalyse mit Mikroorganismen / Project co-leader / Project completed
• Firmenich CTI 25929.2 / Deputy project leader / Project completed

Publications

• Papadopoulou, Athena; Peters, Christin; Borchert, Sonja; Steiner, Kerstin; Buller, Rebecca,

  2022.

  Development of an ene reductase-based biocatalytic process for the production of flavor compounds.

  Organic Process Research & Development.

  26(7), pp. 2102-2110.

  Available from: https://doi.org/10.1021/acs.oprd.2c00096

• Aregger, David; Peters, Christin; Buller, Rebecca,

  2020.

  Characterization of the novel ene reductase Ppo-Er1 from paenibacillus polymyxa.

  Catalysts.

  10(2).

  Available from: https://doi.org/10.3390/catal10020254

• Peters, Christin; Frasson, David; Sievers, Martin; Buller, Rebecca,

  2019.

  Novel Old Yellow Enzyme subclasses.

  ChemBioChem.

  Available from: https://doi.org/10.1002/cbic.201800770

• Peters, Christin; Buller, Rebecca,

  2019.

  Industrial application of 2-oxoglutarate-dependent oxygenases.

  Catalysts.

  9(3), pp. 221-240.

  Available from: https://doi.org/10.3390/catal9030221

• Peters, Christin; Buller, Rebecca,

  2019.

  Linear enzyme cascade for the production of (–)-iso-isopulegol.

  Zeitschrift für Naturforschung C.

  74(3-4).

  Available from: https://doi.org/10.1515/znc-2018-0146

Publications before appointment at the ZHAW

C. Peters, F. Rudroff, M. D. Mihovilovic, U. T. Bornscheuer. Fusion proteins of an enoate reductase and a Baeyer-Villiger monooxygenase facilitate the synthesis of chiral lactones (2017), Biol Chem., 398, 31-37.

A. Beier, S. Bordewick, M. Genz, S. Schmidt, T. van den Bergh, C. Peters, H. J. Joosten, U. T. Bornscheuer, Switch in cofactor specificity of a Baeyer-Villiger Monooxygenase (2016) ChemBioChem, 17, 2312-2315,

L. Skalden, C. Peters, L. Ratz, U. T. Bornscheuer. Synthesis of (1R,3R)-1-amino-3-methylcyclohexane by an enzyme cascade reaction(2016),Tetrahedron, 72, 7207–7211.

L. Skalden, C. Peters, J. Dickerhoff, A. Nobili, H. J. Joosten, K. Weisz, M. Höhne, U. T. Bornscheuer. Two subtle amino acid changes in a transaminase substantially enhance or invert enantiopreference in cascade syntheses (2015), ChemBioChem, 16, 1041-1045

J. Muschiol*, C. Peters*, N. Oberleitner, M. D. Mihovilovic, U. T. Bornscheuer, F. Rudroff. Cascade catalysis – strategies and challenges en route to preparative synthetic biology (2015), Chem. Comm., 51, 5798-5811 (* Joint first authors)

N. Oberleitner, C. Peters, F. Rudroff, U.T. Bornscheuer, M.D. Mihovilovic. In vitro characterization of an enzymatic redox cascade composed of an alcohol dehydrogenase, enoate reductases and a Baeyer-Villiger monooxygenase (2014), J. Biotechnol., 192, 393-399

C. Peters*, R. Kölzsch*, M. Kadow, L. Skalden, F. Rudroff, M.D. Mihovilovic, U.T. Bornscheuer. Identification, characterization and application of three enoate reductases from P. putida in in vitro enzyme cascade reactions (2014), ChemCatChem, 6, 1021-1027 (* Joint first authors)

M. Gall, M. Thomsen, C. Peters, I.V. Pavlidis, P. Jonczyk, P.P. Grünert, S. Beutel, T. Scheper, E. Gross, M. Backes, J.P. Ley, J.M. Hilmer, G. Krammer, G.J. Palm, W. Hinrichs, U.T. Bornscheuer. Enzymatic conversion of flavonoids using bacterial chalcone isomerase and enoate reductase (2014) Ang. Chem. Int. Ed. 53, 1439-1442

N. Oberleitner*, C. Peters*, J. Muschiol, M. Kadow, S. Saß, T. Bayer, P. Schaaf, N. Iqbal, F. Rudroff, M.D. Mihovilovic, U.T. Bornscheuer. An enzymatic toolbox for cascade reactions: a showcase for an in vivo redox sequence in asymmetric synthesis (2013), ChemCatChem, 5, 3524-3528 (* Joint first authors)

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