Dr. Evelyn Wolfram

Dr. Evelyn Wolfram
ZHAW
School of Life Sciences and Facility Management
Section Natural Product Chemistry and Phytopharmacy
Einsiedlerstrasse 29
8820 Wädenswil
Personal profile
Position at the ZHAW
Lecturer in Natural Products Chemistry and Phytopharmacy Research Group
www.zhaw.ch/icbt/phytopharmazie
Expertise and research interests
Phytochemical Analysis, Quality Control and Pharmacopeial methods in Phytopharmacy, Cosmetics and Health Food, Extraction Process Development and Optimization, In process Control, In vitro Propagation of Medicinal Plants,Bioautography, Effect-Directed Analysis, UHPLC, HPLC, HPTLC, Method Development via Quality by Design, Quality Assurance and Standardization in Phytotherapy, Biotechnology of Medicinal Plants, Quality Management
Educational background
PhD in Biotechnology, Research Centre Jülich and Technical University of Munich
Master of Science in Civil and Environmental Engineering, University of Massachusetts, Amherst.
Dipl.-Ing. Environmental Engineering, Technical University of Berlin
Professional milestones
Cytos Biotechnology AG, Schlieren Schweiz
Emil Flachsmann AG/Frutarom Inc., Wädenswil Schweiz
Cosmetochem AG, Steinhausen Schweiz
Ricola Group AG, Schweiz
Associate Professor at the Alexandru Ioan Cuza University, Iasi Romania
Associate Professor at the Ovidius Universität, Constanta Romania
Membership of networks
- Schweizerische Medizinische Gesellschaft für Phytotherapie
- Gesellschaft für Arzneipflanzenforschung
- Gesellschaft Schweizerischer Kosmetik-Chemiker
- Gesellschaft für Chemische Technik und Biotechnologie e.V.
- Phytonetzwerk Schweiz
- Phytochemical Society of Europe
- ESCOP Scientific Committee
Projects
- Phytopharma Kurse / Deputy project leader / Project ongoing
- Computational literature-based natural product drug discovery / Team member / Project completed
- GACP in Cannabis cultivation / Deputy project leader / Project completed
- Biophilia Office / Project co-leader / Project completed
- planar-YES - neuartiges Testsystem auf estrogene Wirkung in Umwelt- und Lebensmittelproben / Team member / Project completed
- BIOPAC (Biopolymer based bioactive food packaging) / Team member / Project completed
- Internationaler Kongress Phytotherapie 2014 / Team member / Project completed
Publications
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Lardos, Andreas; Aghaebrahimian, Ahmad; Koroleva, Anna; Sidorova, Julia; Wolfram, Evelyn; Anisimova, Maria; Gil, Manuel,
2022.
Frontiers in Bioinformatics.
2(827207).
Available from: https://doi.org/10.3389/fbinf.2022.827207
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Trifan, Adriana; Zengin, Gokhan; Sinan, Kouadio Ibrahime; Esslinger, Nils; Grubelnik, Andreas; Wolfram, Evelyn; Skalicka-Woźniak, Krystyna; Minceva, Mirjana; Luca, Simon Vlad,
2021.
Plants.
10(9), pp. 1825.
Available from: https://doi.org/10.3390/plants10091825
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Trifan, Adriana; Skalicka-Woźniak, Krystyna; Granica, Sebastian; Czerwińska, Monika E.; Kruk, Aleksandra; Marcourt, Laurence; Wolfender, Jean-Luc; Wolfram, Evelyn; Esslinger, Nils; Grubelnik, Andreas; Luca, Simon Vlad,
2020.
Journal of Ethnopharmacology.
262(113169).
Available from: https://doi.org/10.1016/j.jep.2020.113169
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Trifan, Adriana; Wolfram, Evelyn; Esslinger, Nils; Grubelnik, Andreas; Skalicka‐Woźniak, Krystyna; Minceva, Mirjana; Luca, Simon Vlad,
2020.
Phytochemical Analysis.
32(4), pp. 482-494.
Available from: https://doi.org/10.1002/pca.2996
-
Ribeiro Neto, José Antônio; Pimenta Tarôco, Bruna Renata; Batista dos Santos, Hélio; Thomé, Ralph Gruppi; Wolfram, Evelyn; Maciel de A. Ribeiro, Rosy Iara,
2020.
Journal of Ethnopharmacology.
260(112547).
Available from: https://doi.org/10.1016/j.jep.2020.112547
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Iliescu, Iolanda Alca; Peter, Samuel; Albert, Ina; Skalicka‐Woźniak, Krystyna; Miron, Anca; Luca, Simon Vlad; Wolfram, Evelyn,
2020.
Chemistry & Biodiversity.
17(12), pp. e2000644.
Available from: https://doi.org/10.1002/cbdv.202000644
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Stuby, Johann; Gravestock, Isaac; Wolfram, Evelyn; Pichierri, Giuseppe; Steurer, Johann; Burgstaller, Jakob M.,
2019.
Appetite-suppressing and satiety-increasing bioactive phytochemicals : a systematic review.
Nutrients.
11(9), pp. 2238.
Available from: https://doi.org/10.3390/nu11092238
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Trifan, Adriana; Vasincu, Alexandru; Luca, Simon Vlad; Neophytou, Christiana; Wolfram, Evelyn; Opitz, Sebastian; Sava, Daciana; Bucur, Laura; Cioroiu, Bogdan I.; Miron, Anca; Aprotosoaie, Ana Clara; Cioanca, Oana; Hancianu, Monica; Jitareanu, Alexandra; Constantinou, Andreas I.,
2019.
Food and Chemical Toxicology.
134(110820).
Available from: https://doi.org/10.1016/j.fct.2019.110820
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Navikaite-Snipaitiene, Vesta; Ivanauskas, Liudas; Jakstas, Valdas; Rüegg, Nadine; Rutkaite, Ramune; Wolfram, Evelyn; Yildirim, Selçuk,
2018.
Meat Science.
145, pp. 9-15.
Available from: https://doi.org/10.1016/j.meatsci.2018.05.015
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Trendafilova, Antoaneta; Todorova, Milka; Genova, Victoria; Peter, Samuel; Wolfram, Evelyn; Danova, Kalina; Evstatieva, Luba,
2018.
Phenolic profile of Artemisia alba Turra.
Chemistry & Biodiversity.
15(7).
Available from: https://doi.org/10.1002/cbdv.201800109
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Trifan, Adriana; Opitz, Sebastian; Josuran, Roland; Grubelnik, Andreas; Esslinger, Nils; Peter, Samuel; Bräm, Sarah; Meier, Nadja; Wolfram, Evelyn,
2017.
Food and Chemical Toxicology.
112, pp. 178-187.
Available from: https://doi.org/10.1016/j.fct.2017.12.051
-
Meier, Nadja; Meier, Beat; Peter, Samuel; Wolfram, Evelyn,
2017.
Molecules.
22(11).
Available from: https://doi.org/10.3390/molecules22111838
-
Wolfram, Evelyn; Bräm, Sarah,
2017.
Recent advances in effect-directed enzyme assays based on thin-layer chromatography.
Phytochemical Analysis.
28(2), pp. 74-86.
Available from: https://doi.org/10.1002/pca.2669
-
Bucar, Franz; Wolfram, Evelyn,
2017.
Bioassay-coupled chromatography : challenges and applications in natural product research.
Phytochemical Analysis.
28(2), pp. 73.
Available from: https://doi.org/10.1002/pca.2675
-
Peter, Samuel; Meier, Nadja; Wolfram, Evelyn; Meier, Beat,
2017.
Journal of Planar Chromatography - Modern TLC.
30(4), pp. 238-244.
Available from: https://doi.org/10.1556/1006.2017.30.4.1
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Danova, Kalina; Todorova, Milka; Trendafilova, Antoaneta; Wolfram, Evelyn; Evstatieva, Luba; Aneva, Ina; Koleva, Petya; Meier, Beat,
2016.
Biotechnological yield of phytopharmaceuticals of valuable Balkan medicinal plants.
Planta Medica.
82(S 01).
Available from: https://doi.org/10.1055/s-0036-1596790
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Pedrussio, Simona; Kroslakova, Ivana; Wolfram, Evelyn,
2016.
Phytochemical Analysis.
27(3-4), pp. 222-228.
Available from: https://doi.org/10.1002/pca.2621
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Wolfram, Evelyn; Bräm, Sarah; Todorova, Milka; Trendafilova, Antoaneta; Alvarez, Andres; Ortega, David; Koleva, Petya; Danova, Kalina,
2016.
Planta Medica.
82(S 01).
Available from: https://doi.org/10.1055/s-0036-1596387
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Steiner, Manuela; Peter, Samuel; Wolfram, Evelyn; Falch, Beatrix; Meier, Beat,
2016.
Modernisierung der Monografien für Thymianfluidextrakt und Thymiansirup der Schweizer Pharmakopöe.
Zeitschrift für Phytotherapie.
37(P24).
Available from: https://doi.org/10.1055/s-0036-1584487
-
Peter, Samuel; Meier, Nadja; Josic, Gojko; Meier, Beat; Wolfram, Evelyn,
2016.
Planta Medica.
81(S 01).
Available from: https://doi.org/10.1055/s-0036-1597006
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Braun, Kathrin; Peter, Samuel; Wolfram, Evelyn; Falch, Beatrix; Meier, Beat,
2016.
Zeitschrift für Phytotherapie.
37(V30).
Available from: https://doi.org/10.1055/s-0036-1584455
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Koleva, Petya; Wolfram, Evelyn; Pedrussio, Simona; Raynova, Yuliana; Evstatieva, Luba; Danova, Kalina,
2015.
In vitro culture development and polyphenolics production of Artemisia alba Turra.
Journal of Biosciences and Biotechnology.
pp. 131-136.
Available from: https://doi.org/10.21256/zhaw-4128
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Meier, Nadja; Peter, Samuel; Meier, Beat; Wolfram, Evelyn,
2015.
Planta Medica.
81(PW_196).
Available from: https://doi.org/10.1055/s-0035-1565820
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Wolfram, Evelyn; Bräm, Sarah; Danova, Kalina; Meier, Beat,
2015.
Planta Medica.
81(SL4B_05).
Available from: https://doi.org/10.1055/s-0035-1565330
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Todorova, Milka; Trendafilova, Antoaneta; Danova, Kalina; Simmons, Luke; Wolfram, Evelyn; Meier, Beat; Riedl, Rainer; Evstatieva, Luba,
2015.
Highly oxygenated sesquiterpenes in Artemisia alba Turra.
Phytochemistry.
110, pp. 140-149.
Available from: https://doi.org/10.1016/j.phytochem.2014.12.008
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Könye, Rita; Peter, Samuel; György, Zsusanna; Wolfram, Evelyn; Danova, Kalina,
2015.
Optimization of an UHPLC method for flavonoids from Hypericum species.
Planta Medica.
81(PW_194).
Available from: https://doi.org/10.1055/s-0035-1565818
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Iliescu, Iolanda Alca; Bräm, Sarah; Peter, Samuel; Meier, Nadja; Albert, Ina; Miron, Anca; Wolfram, Evelyn,
2015.
Planta Medica.
81(PW_208).
Available from: https://doi.org/10.1055/s-0035-1565832
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González, Benita; Vogel, Hermine; Razmilic, Iván; Wolfram, Evelyn,
2015.
Industrial Crops and Products.
76, pp. 158-165.
Available from: https://doi.org/10.1016/j.indcrop.2015.06.038
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Danova, Kalina; Markovska, Yiuliana; Trendafilova, Antoaneta; Todorova, Milka; Wolfram, Evelyn,
2015.
Planta Medica.
81(PW_04).
Available from: https://doi.org/10.1055/s-0035-1565628
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Wolfram, Evelyn; Danova, Kalina; Könye, Rita; Pedrussio, Simona; Aneva, Ina; Evstatieva, Ljuba; Bräm, Sarah; Meier, Beat,
2014.
Planta Medica.
80(16/P2B62).
Available from: https://doi.org/10.1055/s-0034-1394939
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Treneva, G.; Markovska, Yuliana; Wolfram, Evelyn; Danova, Kalina,
2014.
Bulgarian Journal of Agricultural Science.
20(Supplement 1), pp. 46-50.
Available from: https://doi.org/10.21256/zhaw-4132
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Ştefanache, Camelia Paula; Tănase, Cătălin; Wolfram, Evelyn; Dănilă, Doina,
2014.
Journal of Plant Development.
21, pp. 3-13.
Available from: https://doi.org/10.21256/zhaw-1695
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Rosenthal, Martin Immanuel; Wolfram, Evelyn; Peter, Samuel; Meier, Beat,
2014.
Journal of Natural Products.
77(3), pp. 489-496.
Available from: https://doi.org/10.1021/np400736s
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Stefanache, Camelia Paula; Imseng, Nicole; Meier, Beat; Tanase, Catalin; Eibl-Schindler, Regine; Peter, Samuel; Wolfram, Evelyn,
2013.
Planta Medica.
79(13).
Available from: https://doi.org/10.1055/s-0033-1352447
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Markovska, Yuliana; Raynova, Yvanka B.; Idakieva, Krassimira; Todorova, Milka; Wolfram, Evelyn; Danova, Kalina,
2013.
Planta Medica.
79(13/PN20).
Available from: https://doi.org/10.1055/s-0033-1352364
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Todorova, Milka; Trendafilova, Antoaneta; Evstatieva, Ljuba; Simmons, Thomas Luke; Wolfram, Evelyn; Danova, Kalina,
2013.
Highly oxygenated sesquiterpenes from the aerial parts of Artemisia alba Turra.
Planta Medica.
79(13/PI107).
Available from: https://doi.org/10.1055/s-0033-1352196
-
Rosenthal, Martin Immanuel; Wolfram, Evelyn; Meier, Beat,
2013.
New HPLC-method to determine Frangulin A and B as well as Glucofrangulin A and B in Frangulae cortex.
Planta Medica.
79(13/PK33).
Available from: https://doi.org/10.1055/s-0033-1352293
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Rosenthal, Martin Immanuel; Wolfram, Evelyn; Meier, Beat,
2013.
New UHPLC – method to determine Aloin A and B in Aloe capensis.
Planta Medica.
79(PK34).
Available from: https://doi.org/10.1055/s-0033-1352294
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Danova, Kalina; Evstatieva, Ljuba N.; Todorova, Milka; Trendafilova, Antoaneta; Wolfram, Evelyn,
2013.
Planta Medica.
79(13/PN21).
Available from: https://doi.org/10.1055/s-0033-1352365
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Wolfram, Evelyn; Hostettler, Lu; Peter, Samuel; Todorova, Milka; Trendafilova, Antoaneta; Danova, Kalina,
2013.
Planta Medica.
79(13/PN119).
Available from: https://doi.org/10.1055/s-0033-1352461
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Reich, Eike; Schibli, Anne; Widmer, Valeria; Jorns, Ruth; Wolfram, Evelyn; DeBatt, Alison,
2007.
HPTLC methods for identification of green tea and green tea extract.
Journal of Liquid Chromatography & Related Technologies.
29(14), pp. 2141-2151.
Available from: https://doi.org/10.1080/15512160600760293
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Haberland, Jürgen; Kriegesmann, A.; Wolfram, Evelyn; Hummel, Werner; Liese, Andreas,
2002.
Diastereoselective synthesis of optically active (2R,5R)-hexanediol.
Applied Microbiology and Biotechnology.
58(5), pp. 595-599.
Available from: https://doi.org/10.1007/s00253-002-0936-5
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Garvey, Elisa; Tobiason, John E.; Hayes, Michael; Wolfram, Evelyn; Reckhow, David A.; Male, James W.,
1998.
Coliform transport in a pristine reservoir : modeling and field studies.
Water Science and Technology.
37(2), pp. 137-144.
Available from: https://doi.org/10.1016/S0273-1223(98)00048-1
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Wolfram, Evelyn P.,
2002.
Parallele Substratkontrolle in Bioreaktoren mit geringem Volumen.
Forschungszentrum Jülich, Zentralbibliothek.
Berichte des Forschungszentrums Jülich ; 3982.
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Wolfram, Evelyn; Trifan, Adriana,
2018.
Computational aids for assessing bioactivities
.
In:
Sarker, Satyajit; Nahar, Lutfun, eds.,
Computational phytochemistry.
Amsterdam:
Elsevier.
pp. 277-300.
Available from: https://doi.org/10.1016/B978-0-12-812364-5.00010-9
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Trifan, A; Luca, SV; Wolfram, E; Vasincu, A; Opitz, EWS; Aprotosoaie, AC; Miron, A; Jitareanu, A; Neophytou, C; Constantinou, IA,
2019.
In:
67th Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA), Innsbruck, Austria, 1-5 September 2019.
Stuttgart:
Thieme.
pp. 1524-1525.
Available from: https://doi.org/10.1055/s-0039-3400023
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Merki, Rebekka; Schönborn, Andreas; Pihan, Lisa-Anna-Maria; Wolfram, Evelyn,
2019.
Screening for active substances with TLC bioautography : challenges with artefacts [poster].
In:
12th BioDetectors Conference 2019 : Abstract book.
12th BioDetectors Conference 2019, Vienna, Austria, 26-27 September 2019.
Vienna:
BioDetection Systems.
-
Schenk, A; Ziegler, LN; Meier, Nadja; Peter, Samuel; Wolfram, Evelyn,
2017.
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608215
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Wolfram, Evelyn; Peter, Samuel; Todorova, M; Trendafilova, A; Motyka, V; Dobrev, P; Danova, Kalina,
2017.
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608367
-
Bräm, Sarah; Wolfram, Evelyn,
2017.
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608486
-
Meier, Nadja; Meier, Beat; Peter, Samuel; Wolfram, Evelyn,
2017.
HPTLC fingerprint method for the detection of sennosides in Senna dry extracts [poster].
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608524
-
Meier, Nadja; Meier, Beat; Peter, Samuel; Josic, Goijko; Wolfram, Evelyn,
2017.
Photostability of sennosides in solution and their degradation products 1 [poster].
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608273
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Danova, Kalina; Wolfram, Evelyn; Pedrussio, Simona; Koleva, Petya; Aneva, Ina; Evstatieva, Luba,
2017.
Biotechnological development and biological activity of Balkan endemic Sideritis scardica Griesb. [poster].
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608366
-
Wolfram, Evelyn,
2017.
Contributions to regulation of herbal medicinal products from scientific institutions [paper].
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608025
-
Wolfram, Evelyn; Meier, Nadja; Peter, Samuel; Meier, Beat,
2017.
In:
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608528
-
Vahekeni, N; Neto Pedro, M; Kayimbo Malilo, K; van Eeuwijk, P; Mäser, P; João Pedro, G; Théophile, J; Wolfram, Evelyn; da Costa, E; Falquet, J,
2017.
Use of herbal medicine in the management of trypanosomiasis in Angola [paper].
In:
Planta Medica International Open.
65th International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research (GA 2017), Basel, 3-6 September 2017.
Thieme.
Available from: https://doi.org/10.1055/s-0037-1608565
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Yildirim, Selçuk; Wolfram, Evelyn; Rüegg, Nadine,
2016.
Polysaccharide and essential oils coatings for active food packaging materials [paper].
In:
Baltic polymer symposium 2016: Klaipėda, September 21-24, 2016 : programme and abstracts.
16th Baltic Polymer Symposium, Klaipėda, 21-24 September 2016.
Kaunas:
Kaunas University of Technology.
pp. 88.
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Wolfram, Evelyn,
2015.
Der Medizinnobelpreis 2015 – Auswirkungen auf die Phytopharmazie?.
Schweizerische Zeitschrift für Ganzheitsmedizin.
27(6), pp. 320-321.
Available from: https://doi.org/10.1159/000441870
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Stefanache, Camelia Paula; Peter, Samuel; Meier, Beat; Danila, Doina; Tanase, Catalin; Wolfram, Evelyn,
2015.
Revista de Chimie.
66(5), pp. 784-787.
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Rosenthal, Martin Immanuel; Wolfram, Evelyn; Meier, Beat,
2014.
An HPLC method to determine sennoside A and sennoside B in Sennae fructus and Sennae folium.
Pharmeuropa Bio & Scientific Notes.
pp. 92-102.
-
Wolfram, Evelyn; Peter, Samuel; Meier, Beat,
2014.
In:
Phytochemistry in Medicine and Pharmacognosy, Piatra-Neamt, 27-30 April 2014.
-
Treneva, Galina; Markovska, Yuliana; Wolfram, Evelyn; Danova, Kalina,
2013.
In:
Book of Abstracts Vol. IV.
Bioscience - Development and new Opportunities: Kliment's Days, Sofia, Bulgaria, 20-22 November 2013.
-
Wolfram, Evelyn; Meier, Beat; Danova, Kalina,
2013.
In:
2nd GRF One Health Summit 2013, Davos, 17-20 November 2013.
-
Wolfram, Evelyn; Aus dem Siepen, Brigitte; Lindner, Michèle,
2013.
.
In:
Kosmetikjahrbuch 2014 : FIT – Formulierungen, Inhaltsstoffe, Technologie.
Augsburg:
SOFW.
-
Wolfram, Evelyn; Spriano, Daniela; Meier, Beat,
2011.
Extract and extract might not be the same : evaluation of the quality of plant extracts
.
In:
Kosmetikjahrbuch 2011/2012 : the green book of cosmetics.
Augsburg:
Verlag für Chemische Industrie.
-
Wolfram, Evelyn; Gonzàlez López, B.; Hostettler, Lu; Meier, Beat; Vogel, Hermine,
2013.
In:
61st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Münster, Germany, 1-5 September 2013.
Thieme.
Available from: https://doi.org/10.1055/s-0033-1352304
Patents and patent applications
-
Wolfram, Evelyn; Franz, Andreas; Weuster-Botz, Dirk; Wandrey, Christian; Arnold, Matthias,
2001.
Patent number DE10024992 A1
(2001-12-06)
.
Available from: https://worldwide.espacenet.com/patent/search?q=pn%3DDE10024992A1