Chemistry for the Life Sciences
The Master’s thesis is at the heart of your studies. You select modules from Entrepreneurial Skills and Advanced Life Science Skills at an early stage to prepare you for work on your thesis. From the start you are part of a research group at the Institute for Chemistry and Biological Chemistry in Wädenswil or in an external company, organisation or research institute. On the basis of your research you answer specific questions and work out solutions which are relevant for research, business and /or society, often in cooperation with national or international partners. The thesis gives you the opportunity to demonstrate that you can apply the knowledge and competences you have acquired.
Topics for the Master's thesis
You choose the topic of your Master’s thesis in one of the seven centres shown below. You deepen your experimental abilities in your selected area of research and gain detailed insight into the methodologies needed to carry out demanding research projects.
Centre for Organic and Medicinal Chemistry
Contact: Prof. Dr. Rainer Riedl
- Design and synthesis of novel inhibitors for therapeutically relevant drug targets (details).
- Linear and cyclic peptides and peptidomimetics as inhibitors of protein-protein-interactions.
- Computer aided and fragment based drug design.
- Synthesis of enzyme inhibitors by dynamic combinatorial chemistry.
Centre for Biochemistry
Contact: Prof. Dr. Christiane Zaborosch
- Recombinant Protein Technology and Downstream Processing: Development and optimisation of purifications of recombinant proteins.
- Bioanalytics – Characterization of proteins regarding identity, purity, concentration, biological activity and stability: Determination of kinetic parameters and of affinities of protein-protein interactions using label-free surface plasmon resonance (SPR) measurements on a Biacore T200.
- Bioanalytics – Development of specific assays using immunological methods such as ELISA, development of analytics using mass spectrometry or capillary electrophoresis: Characterization of glycan microheterogeneities of recombinant glycoproteins.