Prof. Dr. Michael Raghunath

• Endless spheroid / Project leader / Project completed
• Transglutaminase crosslinking potential / Project leader / Project completed
• Bioprinting of vascular structures / Project leader / Project completed

• Kopanska, Katarzyna S.; Rimann, Markus; Laternser, Sandra; Raghunath, Michael,

  2019.

  Advanced in vitro models analysis.

  Alternatives to Animal Experimentation.

  36(1),

  pp.144-147.

  Available from: https://doi.org/10.14573/altex.1812131

• Coentro, João Q.; Pugliese, Eugenia; Hanley, Geoffrey; Raghunath, Michael; Zeugolis, Dimitrios I.,

  2018.

  Current and upcoming therapies to modulate skin scarring and fibrosis.

  Advanced Drug Delivery Reviews.

  Available from: https://doi.org/10.1016/j.addr.2018.08.009

• Arai, Satoshi; Kriszt, Rókus; Harada, Kazuki; Looi, Liang‐Sheng; Matsuda, Shogo; Wongso, Devina; Suo, Satoshi; Ishiura, Shoichi; Tseng, Yu‐Hua; Raghunath, Michael; Ito, Toshiro; Tsuboi, Takashi; Kitaguchi, Tetsuya,

  2018.

  RGB‐Color intensiometric indicators to visualize spatiotemporal dynamics of ATP in single cells.

  Angewandte Chemie: International Edition.

  57(34),

  pp.10873-10878.

  Available from: https://doi.org/10.1002/anie.201804304

• Raghunath, Michael; Rimann, Markus; Kopanska, Katarzyna S.; Laternser, Sandra,

  2018.

  TEDD annual meeting with 3D bioprinting workshop.

  Chimia.

  72(1-2),

  pp.76-79.

  Available from: https://doi.org/10.2533/chimia.2018.76

• Sorushanova, Anna; Delgado, Luis M.; Wu, Zhuning; Shologu, Naledi; Kshirsagar, Aniket; Raghunath, Rufus; Mullen, Anne M.; Bayon, Yves; Pandit, Abhay; Raghunath, Michael; Zeugolis, Dimitrios I.,

  2018.

  The collagen suprafamily : from biosynthesis to advanced biomaterial development.

  Advanced Materials.

  Available from: https://doi.org/10.1002/adma.201801651

• Blocki, Anna; Beyer, Sebastian; Jung, Friedrich; Raghunath, Michael,

  2018.

  The controversial origin of pericytes during angiogenesis : implications for cell-based therapeutic angiogenesis and cell-based therapies.

  Clinical Hemorheology and Microcirculation.

  69(1-2),

  pp.215-232.

  Available from: https://doi.org/10.3233/CH-189132

• Pugliese, Eugenia; Coentro, João Q.; Raghunath, Michael; Zeugolis, Dimitrios I.,

  2018.

  Wound healing and scar wars.

  Advanced Drug Delivery Reviews.

  129.

  Available from: https://doi.org/10.1016/j.addr.2018.05.010

• Goralczyk, Anna; van Vijven, Marc; Koch, Mathilde; Badowski, Cedric; Yassin, M. Shabeer; Toh, Sue-Anne; Shabbir, Asim; Franco-Obregón, Alfredo; Raghunath, Michael,

  2017.

  TRP channels in brown and white adipogenesis from human progenitors : new therapeutic targets and the caveats associated with the common antibiotic, streptomycin.

  The FASEB Journal.

  31(8).

  Available from: https://doi.org/10.1096/fj.201601081RR

• Hou, Yanyan; Kitaguchi, Tetsuya; Kriszt, Rókus; Tseng, Yu-Hua; Raghunath, Michael; Suzuki, Madoka,

  2017.

  Ca2+-associated triphasic pH changes in mitochondria during brown adipocyte activation.

  Molecular Metabolism.

  6(8),

  pp.797-808.

  Available from: https://doi.org/10.1016/j.molmet.2017.05.013

• Samsonraj, Rebekah M.; Raghunath, Michael; Nurcombe, Victor; Hui, James H.; van Wijnen, Andre J.; Cool, Simon M.,

  2017.

  Concise review : multifaceted characterization of human mesenchymal stem cells for use in regenerative medicine.

  Stem Cells Translational Medicine.

  6(12),

  pp.2173-2185.

  Available from: https://doi.org/10.1002/sctm.17-0129

• Patrikoski, Mimmi; Hui Ching Lee, Michelle; Mäkinen, Laura; Ang, Xiu Min; Mannerström, Bettina; Raghunath, Michael; Miettinen, Susanna,

  2017.

  Effects of macromolecular crowding on human adipose stem cell culture in fetal bovine serum, human serum and defined xeno-free/serum-free conditions.

  Stem Cells International.

  2017(6909163).

  Available from: https://doi.org/10.1155/2017/6909163

• Kriszt, Rókus; Arai, Satoshi; Itoh, Hideki; Lee, Michelle H.; Goralczyk, Anna G.; Ang, Xiu Min; Cypess, Aaron M.; White, Andrew P.; Shamsi, Farnaz; Xue, Ruidan; Lee, Jung Yeol; Lee, Sung-Chan; Hou, Yanyan; Kitaguchi, Tetsuya; Sudhaharan, Thankiah; Ishiwata, Shin’ichi; Lane, E. Birgitte; Chang, Young-Tae; Tseng, Yu-Hua; Suzuki, Madoka; Raghunath, Michael,

  2017.

  Optical visualisation of thermogenesis in stimulated singlecell brown adipocytes.

  Scientific Reports.

  Available from: https://doi.org/10.1038/s41598-017-00291-9

• Lim, Natalie Sheng Jie; Sham, Adeline; Chee, Stella Min Ling; Chan, Casey; Raghunath, Michael,

  2016.

  Combination of ciclopirox olamine and sphingosine-1-phosphate as granulation enhancer in diabetic wounds.

  Wound Repair and Regeneration.

  24(5),

  pp.795-809.

  Available from: https://doi.org/10.1111/wrr.12463

• H. Lee, Michelle; Goralczyk, Anna G.; Kriszt, Rókus; Ang, Xiu Min; Badowski, Cedric; Li, Ying; Summers, Scott A.; Toh, Sue-Anne; Yassin, M. Shabeer; Shabbir, Asim; Sheppard, Allan; Raghunath, Michael,

  2016.

  ECM microenvironment unlocks brown adipogenic potential of adult human bone marrow-derived MSCs.

  Scientific Reports.

  6(21173).

  Available from: https://doi.org/10.1038/srep21173

• Benny, Paula; Badowski, Cedric; Lane, E. Birgitte; Raghunath, Michael,

  2016.

  Improving 2D and 3D skin in vitro models, using macromolecular crowding.

  Journal of Visualized Experiments: Video Journal.

  2016(114).

  Available from: https://doi.org/10.3791/53642

• Kumar, Pramod; Satyam, Abhigyan; Fan, Xingliang; Rochev, Yury; Rodriguez, Brian J.; Gorelov, Alexander; Joshi, Lokesh; Raghunath, Michael; Pandit, Abhay; Zeugolis, Dimitrios I.,

  2015.

  Accelerated development of supramolecular corneal stromal-like assemblies from corneal fibroblasts in the presence of macromolecular crowders.

  Tissue Engineering - Part C: Methods.

  21(7).

  Available from: https://doi.org/10.1089/ten.TEC.2014.0387

• Movahednia, Mohammad Mehdi; Kidwai, Fahad Karim; Zou, Yu; Tong, Huei Jinn; Liu, Xiaochen; Islam, Intekhab; Toh, Wei Seong; Raghunath, Michael; Cao, Tong,

  2015.

  Differential effects of the extracellular microenvironment on human embryonic stem cells differentiation into keratinocytes and their subsequent replicative lifespan.

  Tissue Engineering - Part A.

  21(7-8).

  Available from: https://doi.org/10.1089/ten.TEA.2014.0551

• Samsonraj, Rebekah M.; Rai, Bina; Sathiyanathan, Padmapriya; Puan, Kia Joo; Rötzschke, Olaf; Hui, James H.; Raghunath, Michael; Stanton, Lawrence W.; Nurcombe, Victor; Cool, Simon M.,

  2015.

  Establishing criteria for human mesenchymal stem cell potency.

  Stem Cells.

  33(6),

  pp.1878-1891.

  Available from: https://doi.org/10.1002/stem.1982

• Sham, Adeline; Martinez, Eliana C.; Beyer, Sebastian; Trau, Dieter W.; Raghunath, Michael,

  2015.

  Incorporation of a prolyl hydroxylase inhibitor into scaffolds : a strategy for stimulating vascularization.

  Tissue Engineering - Part A.

  21(5-6).

  Available from: https://doi.org/10.1089/ten.TEA.2014.0077

• Rashid, Rafi; Chee, Stella Min Ling; Raghunath, Michael; Wohland, Thorsten,

  2015.

  Macromolecular crowding gives rise to microviscosity, anomalous diffusion and accelerated actin polymerization.

  Physical Biology.

  12(3).

  Available from: https://doi.org/10.1088/1478-3975/12/3/034001

• Kumar, Pramod; Satyam, Abhigyan; Fan, Xingliang; Collin, Estelle; Rochev, Yury; Rodriguez, Brian J.; Gorelov, Alexander; Dillon, Simon; Joshi, Lokesh; Raghunath, Michael; Pandit, Abhay; Zeugolis, Dimitrios I.,

  2015.

  Macromolecularly crowded in vitro microenvironments accelerate the production of extracellular matrix-rich supramolecular assemblies.

  Scientific Reports.

  5(8729).

  Available from: https://doi.org/10.1038/srep08729

• Benny, Paula; Badowski, Cedric; Lane, E. Birgitte; Raghunath, Michael,

  2015.

  Making more matrix : enhancing the deposition of dermal-epidermal junction components in vitro and accelerating organotypic skin culture development, using macromolecular crowding.

  Tissue Engineering - Part A.

  21(1-2).

  Available from: https://doi.org/10.1089/ten.TEA.2013.0784

• Blocki, Anna; Beyer, Sebastian; Dewavrin, Jean-Yves; Goralczyk, Anna; Wang, Yingting; Peh, Priscilla; Ng, Michael; Moonshi, Shehzahdi S.; Vuddagiri, Susmitha; Raghunath, Michael; Martinez, Eliana C.; Bhakoo, Kishore K.,

  2015.

  Microcapsules engineered to support mesenchymal stem cell (MSC) survival and proliferation enable long-term retention of MSCs in infarcted myocardium.

  Biomaterials.

  53,

  pp.12-24.

  Available from: https://doi.org/10.1016/j.biomaterials.2015.02.075

• Peh, Priscilla; Lim, Natalie Sheng Jie; Blocki, Anna; Chee, Stella Min Ling; Park, Heyjin Chris; Liao, Susan; Chan, Casey; Raghunath, Michael,

  2015.

  Simultaneous delivery of highly diverse bioactive compounds from blend electrospun fibers for skin wound healing.

  Bioconjugate Chemistry.

  26(7),

  pp.1348-1358.

  Available from: https://doi.org/10.1021/acs.bioconjchem.5b00123

• Blocki, Anna; Wang, Yingting; Koch, Maria; Goralczyk, Anna; Beyer, Sebastian; Agarwal, Nikita; Lee, Michelle; Moonshi, Shehzahdi; Dewavrin, Jean-Yves; Peh, Priscilla; Schwarz, Herbert; Bhakoo, Kishore; Raghunath, Michael,

  2015.

  Sourcing of an alternative pericyte-like cell type from peripheral blood generated with pulsed macromolecular crowding.

  Molecular Therapy.

  23(3),

  pp.510-522.

  Available from: https://doi.org/10.1038/mt.2014.232

• Dewavrin, Jean-Yves; Abdurrahiem, Muhammed; Blocki, Anna; Musib, Mrinal; Piazza, Francesco; Raghunath, Michael,

  2015.

  Synergistic rate boosting of collagen fibrillogenesis in heterogeneous mixtures of crowding agents.

  Journal of Physical Chemistry B.

  119(12),

  pp.4350-4358.

  Available from: https://doi.org/10.1021/jp5077559

• Satyam, Abhigyan; Kumar, Pramod; Fan, Xingliang; Gorelov, Alexander; Rochev, Yury; Joshi, Lokesh; Peinado, Héctor; Lyden, David; Thomas, Benjamin; Rodriguez, Brian; Raghunath, Michael; Pandit, Abhay; Zeugolis, Dimitrios,

  2014.

  Macromolecular crowding meets tissue engineering by self-assembly : a paradigm shift in regenerative medicine.

  Advanced Materials.

  26(19),

  pp.3024-3034.

  Available from: https://doi.org/10.1002/adma.201304428

• Ang, Xiu Min; Lee, Michelle H.C.; Blocki, Anna; Chen, Clarice; Ong, L.L. Sharon; Asada, H. Harry; Sheppard, Allan; Raghunath, Michael,

  2014.

  Macromolecular crowding amplifies adipogenesis of human bone marrow-derived MSCs by enhancing the pro-adipogenic microenvironment.

  Tissue Engineering - Part A.

  20(5-6).

  Available from: https://doi.org/10.1089/ten.tea.2013.0337

• Rashid, Rafi; Beyer, Sebastian; Blocki, Anna; Le Visage, Catherine; Trau, Dieter; Wohland, Thorsten; Raghunath, Michael,

  2014.

  Mitochondrial routing of glucose and sucrose polymers after pinocytotic uptake : avenues for drug delivery.

  Biomacromolecules.

  15(6),

  pp.2119-2127.

  Available from: https://doi.org/10.1021/bm500243m

• Rashid, Rafi; Lim, Natalie Sheng Jie; Chee, Stella Min Ling; Png, Si Ning; Wohland, Thorsten; Raghunath, Michael,

  2014.

  Novel use for polyvinylpyrrolidone as a macromolecular crowder for enhanced extracellular matrix deposition and cell proliferation.

  Tissue Engineering - Part C: Methods.

  20(12).

  Available from: https://doi.org/10.1089/ten.tec.2013.0733

• Dewavrin, Jean-Yves; Hamzavi, Nader; Shim, V.P.W.; Raghunath, Michael,

  2014.

  Tuning the architecture of 3D collagen hydrogels by physiological macromolecular crowding.

  Acta Biomaterialia.

  10(10),

  pp.4351-4359.

  Available from: https://doi.org/10.1016/j.actbio.2014.06.006

• Dewavrin, Jean-Yves; Hamzavi, Nader; Shim, V.P.W.; Raghunath, Michael,

  2014.

  Tuning the architecture of three-dimensional collagen hydrogels by physiological macromolecular crowding.

  Acta Biomaterialia.

  10(10),

  pp.4351-4359.

  Available from: https://doi.org/10.1016/j.actbio.2014.06.006

• Samsonraj, Rebekah M; Raghunath, Michael; Hui, James H; Ling, Ling; Nurcombe, Victor; Cool, Simon M,

  2013.

  Telomere length analysis of human mesenchymal stem cells by quantitative PCR.

  Gene.

  519(2),

  pp.348-355.

  Available from: https://doi.org/10.1016/j.gene.2013.01.039

• Tan, Ariel Bing-Shi; Kress, Sebastian; Castro, Leticia; Sheppard, Allan; Raghunath, Michael,

  2013.

  Cellular re- and de-programming by microenvironmental memory: why short TGFβ1 pulses can have long effects.

  Fibrogenesis & Tissue Repair.

  6(12).

  Available from: https://doi.org/10.1186/1755-1536-6-12

• Lim, Sei Hien; Kim, Choong; Aref, Amir R.; Kamm, Roger D.; Raghunath, Michael,

  2013.

  Complementary effects of prolyl hydroxylase inhibitors and sphingosine 1-phosphate on fibroblasts and endothelial cells in driving capillary sprouting.

  Integrative Biology.

  2013(12),

  pp.1474-1484.

  Available from: https://doi.org/10.1039/C3IB40082D

• Blocki, Anna; Wang, Yingting; Koch, Maria; Peh, Priscilla; Beyer, Sebastian; Law, Ping; Hui, James; Raghunath, Michael,

  2013.

  Not all MSCs can act as pericytes : functional In vitro assays to distinguish pericytes from other mesenchymal stem cells in angiogenesis.

  Stem Cells and Development.

  22(17).

  Available from: https://doi.org/10.1089/scd.2012.0415

• Satyam, A.; Subramanian, G. S.; Raghunath, M.; Pandit, A.; Zeugolis, D. I.,

  2012.

  In vitro evaluation of Ficoll‐enriched and genipin‐stabilised collagen scaffolds.

  Journal of Tissue Engineering and Regenerative Medicine.

  8(3),

  pp.233-241.

  Available from: https://doi.org/10.1002/term.1522

• Zeiger, Adam S.; Loe, Felicia C.; Li, Ran; Raghunath, Michael; Van Vliet, Krystyn J.,

  2012.

  Macromolecular crowding directs extracellular matrix organization and mesenchymal stem cell behavior.

  PLOS ONE.

  7(5),

  pp.e37904.

  Available from: https://doi.org/10.1371/journal.pone.0037904

• Chen, Clarice; Loe, Felicia; Blocki, Anna; Peng, Yanxian; Raghunath, Michael,

  2011.

  Applying macromolecular crowding to enhance extracellular matrix deposition and its remodeling in vitro for tissue engineering and cell-based therapies.

  Advanced Drug Delivery Reviews.

  63(4-5),

  pp.277-290.

  Available from: https://doi.org/10.1016/j.addr.2011.03.003

• Lareu, Ricky R.; Zeugolis, Dimitrios I.; Abu-Rub, Mohammad; Pandit, Abhay; Raghunath, Michael,

  2010.

  Essential modification of the Sircol Collagen Assay for the accurate quantification of collagen content in complex protein solutions.

  Acta Biomaterialia.

  6(8),

  pp.3146-3151.

  Available from: https://doi.org/10.1016/j.actbio.2010.02.004

• Zeugolis, D. I.; Panengad, P. P.; Yew, E. S. Y.; Sheppard, C.; Phan, T. T.; Raghunath, M.,

  2009.

  An in situ and in vitro investigation for the transglutaminase potential in tissue engineering.

  Journal of Biomedical Materials Research.

  92A(4),

  pp.1310-1320.

  Available from: https://doi.org/10.1002/jbm.a.32383

• Raghunath, Michael; Wong, Yuan Sy; Farooq, Muhammad; Gee, Ruowen,

  2009.

  Pharmacologically induced angiogenesis in transgenic zebrafish.

  Biochemical and Biophysical Research Communications.

  378(4),

  pp.766-771.

  Available from: https://doi.org/10.1016/j.bbrc.2008.11.127

• Wang, Z.; Chen, C.; Finger, S. N.; Kwajah M.M, S. d/o; Jung, M.; Schwarz, H.; Swanson, N.; Lareu, R. R.; Raghunath, M.,

  2009.

  Suberoylanilide hydroxamic acid : a potential epigenetic therapeutic agent for lung fibrosis?.

  The European Respiratory Journal.

  34(1),

  pp.145-155.

  Available from: https://doi.org/10.1183/09031936.00084808

• Chen, C.Z.C.; Fish, P.V.; Peng, Y.X.; Wang, Z.B.; Kaar, J.L.; Koepsel, R.R.; Russell, A.J .; Lareu, R.R.; Raghunath, M.,

  2009.

  The Scar‐in‐a‐Jar : studying potential antifibrotic compounds from the epigenetic to extracellular level in a single well.

  British Journal of Pharmacology.

  158(5),

  pp.1196-1209.

  Available from: https://doi.org/10.1111/j.1476-5381.2009.00387.x

• Zeugolis, D. I.; Li, B.; Lareu, R.R.; Chan, C.K.; Raghunath, M.,

  2008.

  Collagen solubility testing, a quality assurance step for reproducible electro-spun nano-fibre fabrication : a technical note.

  Journal of Biomaterials Science, Polymer Edition.

  19(10),

  pp.1307-1317.

  Available from: https://doi.org/10.1163/156856208786052344

• Zeugolis, Dimitrios I.; Khew, Shih T.; Yew, Elijah S.Y.; Ekaputra, Andrew K.; Tong, Yen W.; Yung, Lin-Yue L.; Hutmacher, Dietmar W.; Sheppard, Colin; Raghunath, Michael,

  2008.

  Electro-spinning of pure collagen fibres : just an expensive way to make gelatin?.

  Biomaterials.

  29(15),

  pp.2293-2305.

  Available from: https://doi.org/10.1016/j.biomaterials.2008.02.009

• Badowski, Cedric; Iskander, Aneesa; Gaspar, Diana; Zeugolis, Dimitrios I.; Raghunath, Michael,

  2018.

  Molecular Crowding – (in Cell Culture)

  .

  In:

  Tissue engineering and regeneration : cell engineering and regeneration.

  Springer.

  Reference Series in Biomedical Engineering.

  Available from: https://doi.org/10.1007/978-3-319-37076-7_50-1

• Coentro, João Quintas; Capella-Monsonís, Héctor; Graceffa, Valeria; Wu, Zhuning; Mullen, Anne Maria; Raghunath, Michael; Zeugolis, Dimitrios I.,

  2017.

  Collagen quantification in tissue specimens

  .

  In:

  Fibrosis.

  Springer.

  Methods in Molecular Biology ; 1627.

  Available from: https://doi.org/10.1007/978-1-4939-7113-8_22

• Benny, Paula; Raghunath, Michael,

  2017.

  Making microenvironments : a look into incorporating macromolecular crowding into in vitro experiments, to generate biomimetic microenvironments which are capable of directing cell function for tissue engineering applications.

  Journal of Tissue Engineering.

  Available from: https://doi.org/10.1177/2041731417730467

• Rimann, Markus; Mathes, Stephanie; Raghunath, Michael; Rohrer, Jack,

  2016.

  Zurich university of applied sciences : center for cell biology and tissue engineering [poster].

  In:

  Roche Symposium, Basel, 2016.

• Raghunath, Michael; Rimann, Markus; Mathes, Stephanie; Rohrer, Jack,

  2016.

  Zurich University of Applied Sciences : center for cell biology and tissue engineering [poster].

  In:

  Roche Symposium, Basel, 2016.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula; Raghunath, Michael,

  2017.

  3D bioprinted tissue models for substance testing.

  In:

  International Conference and Exhibition - Society for Laboratory Automation and Screening (SLAS 2017), Washington, USA, 4–8 February 2017.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula; Raghunath, Michael,

  2016.

  Bioprinted tissues for substance evaluation.

  In:

  Biointerfaces International 2016 Conference, Zurich, 23-25 August 2016.

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