Current projects of the Environmental Genomics and Systems Biology Research Group
FoodN’Feed – Local adaptation and sustainability in grain legume cultivation with soybean as a proof of principle
Grain legumes, such as soybeans, faba beans and peas can feed themselves with the help of natural soil bacteria. This reduces the need for synthetic fertilizer and lowers emissions. However, these microbial partnerships remain largely untapped.
Our project identifies the most effective native bacteria and fungi to help Swiss protein crops grow stronger, healthier, and more resilient. Using modern DNA tools, we identify root‑dwelling microbes that truly boost plant performance and select the most promising ones as natural, locally adapted biofertilizers.
By improving upon what already exists in our soils, we aim to increase Switzerland’s self‑sufficiency in protein production, reduce environmental impacts, and support a more sustainable agri‑food system. The most successful microbial communities will then be tested across Europe to strengthen plant‑based protein production in a changing climate.
Project duration: 04/2026–03/2030
Project partner: Ecologie Microbienne - Université Lyon 1
Contracting body: SNF / Project Nr. 10006234
ARTeDNA – Fungal diversity in the Royal Botanical Park of Bhutan: soil eDNA and art for conservation and communication
ARTeDNA is a Swiss-Bhutanese project bringing together ZHAW and Bhutan's National Mushroom Center to map the hidden diversity of fungi in the Royal Botanical Park in Lamperi. Despite 15 years of fieldwork, less than 5% of Bhutan's fungal species are known to science. The project uses DNA extracted directly from soil to detect fungi that traditional surveys miss, while training Bhutanese researchers and using visual arts to share the findings with the wider public.
Project duration: 03/2026–03/2027
Project partners: National Mushroom Center (NMC), Department of Agriculture, Ministry of Agriculture and Livestock (Bhutan)
Funding agency: Leading House South Asia
Chitin integrated seedling pots (CHIPOTS+)
This project originated from an Open Exploration Workshop organized by the Innovation Booster of Future Food Farming, an Innosuisse-funded initiative supporting innovation through idea development and testing. From 2024 to 2027, the Booster aims to connect farmers and citizens to build a more resilient, sustainable Swiss agro-food and nutrition system by fostering co-created, radical solutions through open innovation.
During a visit to the Z’Alpenblick organic farm in Hirzel, we explored the challenges of reconnecting with the soil. Using a problem-based approach and stakeholder mapping, participants from various sectors identified opportunities. This networking led us to submit a proposal for expert support and development.
Selected for further development, our project evolved over eight weeks through three online incubation sessions funded by an innovation voucher. We then pitched the idea to a jury of eleven experts, who awarded us additional funding for continued development over the next year. While the project details remain confidential, it leverages partner expertise to address key challenges aligned with the Innovation Booster’s mission.
Project duration: 12/2024-05/2026
Project partners: Suisse Agro Food Leading House, Innovation Booster Future Food Farming, Swiss Food Research, mycostrat GmbH, swissmycel GmbH
Development of an eDNA method for assessing invertebrate biodiversity in urban areas
As a fundamental basis of life, the sharp decline in biodiversity affects us very directly, and yet preserving it presents us with major challenges. The loss of habitats, particularly in increasingly densely inhabited areas, is one of the main causes of these declines. To counteract these species losses with targeted measures, methods for monitoring biodiversity are essential, and that is precisely where this project comes in. Invertebrates, such as spiders and insects, are also severely affected by these declines. For insects in particular—the most species-rich class of all animals—very large declines have been documented in recent decades.
Like most living organisms, insects and spiders leave traces in their habitats where very small amounts of their DNA can be found. This DNA is also called environmental DNA (eDNA) and is utilized in this project to investigate its potential for assessing biodiversity in urban and urbanized areas. Various techniques are being experimentally tested to extract these DNA traces, and the DNA is sequenced in the laboratory using next-generation sequencing. The goal is to ensure scalability to locations outside the study area.
Project duration: 06/2024-03/2025
Project partner: External
Efficacy of Far-UV-C and development of a rapid test for Botrytis resistance
The spores are eliminated after just 60–120 seconds of UV-C exposure.
The Environmental Genomics and Systems Biology research group at ZHAW is conducting additional studies alongside the Federal Office for Agriculture (FOAG) project, "Non-chemical treatment of strawberry seedlings against Botrytis cinerea". The project includes several modules. One focuses on identifying UV-C wavelengths that are more effective and safer to use (far-UV-C). Unlike conventional UV-C, far-UV-C cannot penetrate human tissue. This module tests the effect of far-UV-C on various pathogens and determines its efficacy. Another module, "Rapid Test Development," involves creating a molecular rapid test to detect Botrytis resistance to botryticides.
Project duration: 11/2022-03/2025
Project partner: Landwirtschaftliche Zentrum Liebegg
List of projects
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Local Adaptation and Sustainability in Grain Legume Cultivation with Soybean as a Proof of Principle (FoodN'Feed)
The project FoodN'Feed aims to fill the gap in the development of native microbial communities for Swiss-adapted sustainable grain legume cultivation by capturing the true nodule rhizobial community and associated root microbiomes for the three most relevant grain legume crops for Switzerland…
current, 04/2026 - 03/2030
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Development of a LAMP assay for selective amplification of DNA from living cells
The detection of bacteria using LAMP is well established and widely applied in clinical and veterinary diagnostics, as well as for pathogen detection in food safety and agriculture. The objective of this project is to focus on detecting viable bacterial cells in seed wash solutions. As a model…
current, 03/2026 - 05/2028
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AQUAPEALTH: Harnessing soilless microbial communities to enhance plant health across different cultivation systems
The AQUAPEALTH aims to develop sustainable IPM strategies, enhance plant health, and bridge the gap between fundamental research and practical applications in soilless systems to enhance plant health, control plant pathogens, and improve resistance to environmental stress.
current, 11/2025 - 04/2027
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CHIPOTS+: Chitin-Integrated Mycelium-Bound Substrate Blocks for Seedling Boosting
The CHIPOTS+ project aims to reduce peat use in seedling production and restore soil fungal systems using chitin-integrated mycelium-bound substrate blocks. These blocks offer environmental benefits, promote plant growth, and induce resistance to pathogens (ZHAW research). Mycostrat GmbH has…
current, 12/2024 - 06/2026
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Development of a biofungicide based on actinobacteria strains isolated from extreme Moroccan ecosystems to protect and improve tomato…
Tomato is a vegetable crop grown in many countries, and its production is constantly increasing. Unfortunately, production can be limited by both abiotic and biotic factors. Fungal pathogens are one of the major factors that reduce crop yield. Botrytis cinerea is a phytopathogenic fungus that causes…
current, 12/2024 - 12/2027
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Loop-mediated isothermal amplification for real-time pathogen screening in soil
The aim of this project is to develop a real-time pathogen screening system for important soil pathogens using loop-mediated isothermal amplification (LAMP) technology. The process will involve the isolation and amplification of DNA from plant, seed or soil samples. A key challenge will be to…
current, 11/2024 - 12/2026
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Long-term conservation of Arctic char (Salvelinus umbla) in Lake Zurich
In order to ensure a stable population of Arctic char in Lake Zurich in the long term, existing measures (fish stocking and artificial spawning grounds) are being evaluated and optimised. The aim is to make recommendations for terminating useless measures, optimising moderate ones and expanding…
current, 05/2024 - 03/2030
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Development of a kit for the detection of leaf spot in turf grass
The objective is to develop a real-time pathogen detection kit for a range of turf grass leaf spot diseases. This kit will feature a straightforward process for DNA extraction and amplification through loop-mediated isothermal amplification (LAMP). It will enable semi-quantitative assessment of…
expired, 04/2024 - 12/2025
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Bioprospecting and genomics of actinobacteria isolated from the Marchica lagoon (ActinOmics)
The massive and excessive use of antibiotics in medicine has led to the emergence and spread of multi-resistant pathogens, rendering treatment with the usual antibiotics ineffective. Added to this phenomenon of antibiotic resistance is the emergence of new infectious diseases, often zoonotic, in…
current, 09/2023 - 05/2026
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Massive detection of tomato brown rugose fruit virus by high-throughput sequencing (ToViPoRe)
Swiss agriculture is at risk with the emergence of a new viral disease epidemic caused by the Tomato Brown Rugose Fruit Virus (ToBRFV), also know as Jordan virus. This plant disease attacking tomato and peppers can lead to a complete yield loss thus generating significant economic losses for Swiss…
expired, 02/2023 - 08/2025
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EBDOmics – Comparative genomics of Enterobacter spp. causing Bulb Decay of Onions
Enterobacter bulb disease of onions (EBDO) is caused by members of the Enterobacter cloacae complex. This includes a diverse group of Enterobacter species that occur as clinical isolates and in the environment. Although EBDO has been known for several years, no systematic study has been conducted on…
expired, 01/2022 - 02/2026
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Turf Pathogen Screening System using Loop Mediated Isothermal Amplification
The objective is the development of a real-time pathogen screening system for a group of global relevant turf grass diseases using loop mediated isothermal amplification, LAMP technology. From a turf sample, DNA isolated and amplified using LAMP. Pathogen occurrence in the sample will be detected…
expired, 12/2021 - 12/2023
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Fire Blight App for Central Asia
Based on the existing tick app in Switzerland, we will develop an app for smartphones that can inform local populations in Central Asia about fire blight, simultaneously allowing a citizen science approach for mapping the spread of this dangerous pome fruit disease. Utilizing the gathered data, a…
expired, 03/2021 - 06/2022
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Antibiotic resistances in Enterobacteria
Atypical Enterobacteria are frequently misidentified in clinical diagnostics due to unsettled taxonomy and noisy reference databases. Despite of their environmental origin, they regularly appear in clinical samples and increasingly display multi-drug resistances (MDRs) that are acquired during…
expired, 12/2020 - 11/2022
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Acceptance of an app for contact-tracing of SARS-CoV-2 in the Swiss population
The survey of 1929 adults in Switzerland in the period from 17 - 26 April 2020 suggests that a large majority of the population in any case or probably intends to a) install an app for contact-tracing of SARS-CoV-2, b) report infections in the app and c) comply with the app's request for contact…
expired, 04/2020 - 09/2020
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Evaluation of benefits and risk of assisted migration in Fagus species
Risk and benefits of assisted introduction of drought-resistant Fagus species in EuropeEuropean beech (Fagus sylvatica) is one of the economically most important broadleaved trees in Europe. Its natural geographical diffusion area is however expected to experience a major shift as a consequence of…
expired, 01/2020 - 12/2022
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A multidisciplinary project to understand the effect of chitin soil amendment on the plant response, natural microbial community and the…
The consumption of fruit and vegetables are considered as important for a healthy and balanced diet and recognized as a significant source of vitamins and fibre. Authorities encourage the consumption of fresh plant produce, but food safety of fresh fruits and vegetables continues to be a major…
expired, 01/2020 - 12/2024
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Silent pathway awakening to discover novel antibacterial compounds from actinomycetes
There is a tremendous need for novel antibiotics due to the global resistance crisis. Actinomycetes are the most important sources of secondary metabolites. They provide an enormous potential to discover novel antibiotics.
expired, 08/2019 - 01/2021
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Fighting bites with bytes: Promoting public health with crowdsourced tick prevention
Ticks are on the rise and transmit several infectious diseases, leading to serious illness or even death. The smartphone App “Zecke–Tick Prevention helps people, to remember the tick bite location and to check it for potential Lyme disease symptoms. In an interdisciplinary approach, ZHAW-scientists…
expired, 07/2019 - 12/2021
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CarbonATE - microbiological methanation
Development of an enzymatic CO2-capture strategy for an optimised microbiological methanation
expired, 03/2019 - 12/2022