Dr. Zrinka Raguz Nakic

Work at ZHAW

Position

Postdoctoral researcher Biosystems Technology

Focus

Metabolic regulation, State of the art genetics, Fermentation, Protein Expression, Mass spectrometry, Data analysis and programing

Education and Continuing education

Education

• Postdoctoral researcher / Institute of Molecular Systems Biology
  ETH Zurich, Switzerland
  04 / 2018 - 10 / 2018
• PhD studies in Molecular Systems Biology / Institute of Molecular Systems Biology, Supervisor Prof. Dr. Uwe Sauer
  ETH Zurich, Switzerland
  11 / 2011 - 04 / 2018
• Masters Degree in Biotechnology
  ESBS Strasbourg (EUCOR), France
  09 / 2007 - 09 / 2011
• Undergraduate studies in Biology
  University of Zurich, Switzerland
  10 / 2005 - 08 / 2007

Projects

• Flow Chemistry für Enzymkaskaden / Team member / Project completed
• Die Exploration der Gen-Harmonisierung / Team member / Project completed
• Impulse - Digitalization in biofabrication: Design, recombinant production and testing of innovative Protein scaffolds as inks for 3D bioprinting / Team member / Project completed
• Plasmid-Toolbox for enzyme cascades / Team member / Project completed

Publications

• Raguz Nakic, Zrinka; Peters, Christin,

  2023.

  Modular cloning by Golden Gate assembly and possible application in pathway design.

  Chimia.

  77(6), pp. 437-441.

  Available from: https://doi.org/10.2533/chimia.2023.437

• Schastnaya, Evgeniya; Raguz Nakic, Zrinka; Gruber, Christoph H.; Doubleday, Peter Francis; Krishnan, Aarti; Johns, Nathan I.; Park, Jimin; Wang, Harris H.; Sauer, Uwe,

  2021.

  Extensive regulation of enzyme activity by phosphorylation in Escherichia coli.

  Nature Communications.

  12(5650).

  Available from: https://doi.org/10.1038/s41467-021-25988-4

Publications before appointment at the ZHAW

• Raguz Nakic, Z., Seisenbacher, G., Posas, F. & Sauer, U. Untargeted metabolomics unravels functionalities of phosphorylation sites in Saccharomyces cerevisiae. BMC Syst. Biol. 10, 1–15 (2016)
• Gonçalves E., Raguz Nakic Z., Zampieri M., Wagih O., Ochoa D., Sauer U., Beltrao P. & Saez-Rodriguez J. Systematic analysis of transcriptional and post-transcriptional regulation of metabolism in yeast. PLoS Comput Biol. 13, 1-20 (2017)
• Schastnaya, E., Raguz Nakic, Z., Gruber, C.H., Doubleday, P.F., Krishnan, A., Johns, N.I., Park, J., Wang H.H, & Sauer U. Extensive regulation of enzyme activity by phosphorylation in Escherichia coli. Nat Commun 12, 5650 (2021)

Other publications

• Raguz Nakic, Z.; Peters, C. Modular Cloning by Golden Gate Assembly and Possible Application in Pathway Design. Chimia 2023, 77, 437-441.
• Dranseike D, Ota Y, Edwardson TGW, Guzzi EA, Hori M, Nakic ZR, Deshmukh DV, Levasseur MD, Mattli K, Tringides CM, Zhou J, Hilvert D, Peters C, Tibbitt MW. Designed modular protein hydrogels for biofabrication. Acta Biomater. 2024.

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