Development of a point of care device prototype for blood ammonia monitoring
At a glance
- Project leader : Daniel Fehr
- Deputy of project leader : Prof. Dr. Mathias Bonmarin
- Project team : Christian Grossmann Aybar, Raphael Hagen, Dr. Fabrizio Spano, Jan Zwicky
- Project budget : CHF 567'592
- Project status : ongoing
- Funding partner : Innosuisse
- Project partner : Versantis AG
- Contact person : Daniel Fehr
Description
Hyperammonemia and associated neurological manifestations (hepatic encephalopathy) lead to coma and death and incur high costs. It affects 30-45% of cirrhotic patients. A novel portable point of care device based on pH-gradient polymersomes for daily monitoring of ammonia will alleviate the burdens.