Prof. Sven Hirsch PhD

Prof. Sven Hirsch PhD
ZHAW
School of Life Sciences and Facility Management
Institute of Computational Life Sciences
Schloss
8820 Wädenswil
Work at ZHAW
Position
Focus
- Artificial Intelligence (AI) in Medicine, Digital Patient Twin, Biomedical Modeling and Simulation, Digital Health
- Medical imaging analysis & diagnostics systems, Modelling of biomedical processes, Data assimilation and machine intelligence, Sensor and time series analysis
- Aesthetics of digitalisation and its implications on society, Chair for Sciences in the Board of Foundation Insel Hombroich
Teaching
- Lecturer BSc Applied Digital Life Sciences
- Lecturer MSc Computational Life Sciences
- Lecturer University of Zurich (UZH)
Experience
- Right to confer PhD UZH
University Zurich
12 / 2023 - today - Head of Center for Computational Health
ZHAW, Institute of Computational Life Sciences
01 / 2022 - today - Group Head Biomedical Simulation
ZHAW, Institute of Applied Simulation
09 / 2013 - 12 / 2021 - Media artist
self-employed
01 / 2000 - 09 / 2019 - Senior Foresight Consultant, Head of Quantification
Z_punkt, The foresight company
05 / 2008 - 06 / 2017 - Group Leader Biomedical Simulation
ETH Zurich, Computer vision lab (Prof. Székely)
07 / 2008 - 08 / 2013 - Project lead holographic topometry
ViRad Imaging/Uniklinik Düsseldorf/caesar Bonn
02 / 2007 - 08 / 2008 - Assistent holographic facial topometry
Kantonspital Basel
10 / 2003 - 01 / 2007
Education and Continuing education
Education
- PhD / Laser Physics
University Düsseldorf
09 / 2003 - 01 / 2007 - Postgrad. Master / Audiovisual Media
Acedemy for Media Arts, Cologne
09 / 1999 - 09 / 2002 - Physicist, Digital Image Processing and Physiology / Physics
University Heidelberg
09 / 1993 - 07 / 1998 - Vordiplom / Physics
University Mainz
10 / 1991 - 08 / 1993
Continuing Education
- CAS Leadership & Governance for Higher Education
University of Zurich
07 / 2023 - Professor
ZHAW
06 / 2016 - CAS didactics for higher education
PH Zurich
07 / 2015 - PhD Laser Physics
Heinrich Heine University Düsseldorf
01 / 2007
Network
ORCID digital identifier
Social media
Projects
- GEMINI: A Generation of Multi-scale Digital Twins of Ischaemic and Haemorrhagic Stroke Patients / Project leader / ongoing
- Stroke DynamiX – Graphical and Causal Networks for Personalized Stroke Management / Deputy project leader / ongoing
- Digital Health Zurich: a practice lab for patient-centred clinical innovation / Project leader / ongoing
- OSR4H – Open Set Recognition for Hematology / Deputy project leader / completed
- Deep Brain Vessel Profiler / Deputy project leader / completed
- Automated Release Testing System / Team member / completed
- Digital simulation for the tailored production of 3D nanofiber filters and their integration in a full protective suit for pandemic cases / Deputy project leader / completed
- Platform Health / Project leader / completed
- BISTOM – Bayesian Inference with Stochastic Models / Deputy project leader / completed
- A cloud-based IoT approach for food safety and quality prediction / Project leader / completed
- PhD Network in Data Science / Team member / completed
- AneuX / Project leader / completed
Publications
-
Reichl, J.J.; Leifke, M.; Wehrli, S.; Kunz, D.; Geissmann, L.; Broisch, S.; Illien, M.; Wellauer, D.; von Dach, N.; Diener, S.; Manser, V.; Herren, V.; Angerer, A.; Hirsch, S.; Hölz, B.; Eckstein, J.,
2024.
Archives of Public Health.
82(1), pp. 179.
Available from: https://doi.org/10.1186/s13690-024-01409-y
-
Mack, Ines; Juchler, Norman; Rey, Sofia; Hirsch, Sven; Hoelz, Bianca; Eckstein, Jens; Bielicki, Julia,
2022.
Wearable technologies for pediatric patients with surgical infections : more than counting steps?.
Biosensors.
12(8), pp. 634.
Available from: https://doi.org/10.3390/bios12080634
-
Morel, Sandrine; Hostettler, Isabel C.; Spinner, Georg R.; Bourcier, Romain; Pera, Joanna; Meling, Torstein; Alg, Varinder; Houlden, Henry; Bakker, Mark; van’t Hof, Femke; Rinkel, Gabriel; Foroud, Tatiana; Lai, Dongbing; Moomaw, Charles; Worrall, Bradford; Caroff, Jildaz; Constant-dits-Beaufils, Pacôme; Karakachoff, Matilde; Rimbert, Antoine; Rouchaud, Aymeric; Gaal-Paavola, Emilia; Kaukovalta, Hanna; Kivisaari, Riku; Laakso, Aki; Jahromi, Behnam; Tulamo, Riikka; Friedrich, Christoph; Dauvillier, Jerome; Hirsch, Sven; Isidor, Nathalie; Kulcsàr, Zolt; Lövblad, Karl; Martin, Olivier; Machi, Paolo; Mendes Pereira, Vitor; Rüfenacht, Daniel; Schaller, Karl; Schilling, Sabine; Slowik, Agnieszka; Jaaskelainen, Juha; von und zu Fraunberg, Mikael; Jiménez-Conde, Jordi; Cuadrado-Godia, Elisa; Soriano-Tárraga, Carolina; Millwood, Iona; Walters, Robin; The @neurIST project; The ICAN Study Group; Genetics and Observational Subarachnoid Haemorrhage (GOSH) Study Investigators; International Stroke Genetics Consortium (ISGC); Kim, Helen; Redon, Richard; Ko, Nerissa; Rouleau, Guy; Lindgren, Antti; Niemelä, Mika; Desal, Hubert; Woo, Daniel; Broderick, Joseph; Werring, David; Ruigrok, Ynte; Bijlenga, Philippe,
2022.
Intracranial aneurysm classifier using phenotypic factors : an international pooled analysis.
Journal of Personalized Medicine.
12(9), pp. 1410.
Available from: https://doi.org/10.3390/jpm12091410
-
Bakker, Mark K.; van der Spek, Rick A. A.; van Rheenen, Wouter; Morel, Sandrine; Bourcier, Romain; Hostettler, Isabel C.; Alg, Varinder S.; van Eijk, Kristel R.; Koido, Masaru; Akiyama, Masato; Terao, Chikashi; Matsuda, Koichi; Walters, Robin G.; Lin, Kuang; Li, Liming; Millwood, Iona Y.; Chen, Zhengming; Rouleau, Guy A.; Zhou, Sirui; Rannikmäe, Kristiina; Sudlow, Cathie L. M.; Houlden, Henry; van den Berg, Leonard H.; Dina, Christian; Naggara, Olivier; Gentric, Jean-Christophe; Shotar, Eimad; Eugène, François; Desal, Hubert; Winsvold, Bendik S.; Børte, Sigrid; Johnsen, Marianne Bakke; Brumpton, Ben M.; Sandvei, Marie Søfteland; Willer, Cristen J.; Hveem, Kristian; Zwart, John-Anker; Verschuren, W. M. Monique; Friedrich, Christoph M.; Hirsch, Sven; Schilling, Sabine; Dauvillier, Jérôme; Martin, Olivier; Jones, Gregory T.; Bown, Matthew J.; Ko, Nerissa U.; Kim, Helen; Coleman, Jonathan R. I.; Breen, Gerome; Zaroff, Jonathan G.; Klijn, Catharina J. M.; Malik, Rainer; Dichgans, Martin; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Amouyel, Philippe; Debette, Stéphanie; Rinkel, Gabriel J. E.; Worrall, Bradford B.; Pera, Joanna; Slowik, Agnieszka; Gaál-Paavola, Emília I.; Niemelä, Mika; Jääskeläinen, Juha E.; von Und Zu Fraunberg, Mikael; Lindgren, Antti; Broderick, Joseph P.; Werring, David J.; Woo, Daniel; Redon, Richard; Bijlenga, Philippe; Kamatani, Yoichiro; Veldink, Jan H.; Ruigrok, Ynte M.,
2020.
Nature Genetics.
52(12), pp. 1303-1313.
Available from: https://doi.org/10.1038/s41588-020-00725-7
-
Juchler, Norman; Schilling, Sabine; Bijlenga, Philippe; Morel, Sandrine; Rüfenacht, Daniel; Kurtcuoglu, Vartan; Hirsch, Sven,
2020.
Shape irregularity of the intracranial aneurysm lumen exhibits diagnostic value.
Acta Neurochirurgica.
162(9), pp. 2261-2270.
Available from: https://doi.org/10.1007/s00701-020-04428-0
-
Detmer, Felicitas J.; Mut, Fernando; Slawski, Martin; Hirsch, Sven; Bijlenga, Philippe; Cebral, Juan R.,
2020.
Acta Neurochirurgica.
162(3), pp. 553-566.
Available from: https://doi.org/10.1007/s00701-020-04234-8
-
Detmer, Felicitas J.; Lückehe, Daniel; Mut, Fernando; Slawski, Martin; Hirsch, Sven; Bijlenga, Philippe; von Voigt, Gabriele; Cebral, Juan R.,
2020.
Comparison of statistical learning approaches for cerebral aneurysm rupture assessment.
International Journal of Computer Assisted Radiology and Surgery.
15(1), pp. 141-150.
Available from: https://doi.org/10.1007/s11548-019-02065-2
-
Borčinová, Martina; Raschmanová, Hana; Zamora, Iwo; Looser, Verena; Marešová, Helena; Hirsch, Sven; Kyslík, Pavel; Kovar, Karin,
2020.
Production and secretion dynamics of prokaryotic Penicillin G acylase in Pichia pastoris.
Applied Microbiology and Biotechnology.
104(13), pp. 5787-5800.
Available from: https://doi.org/10.1007/s00253-020-10669-x
-
Detmer, Felicitas J.; Hadad, Sara; Chung, Bong Jae; Mut, Fernando; Slawski, Martin; Juchler, Norman; Kurtcuoglu, Vartan; Hirsch, Sven; Bijlenga, Philippe; Uchiyama, Yuya; Fujimura, Soichiro; Yamamoto, Makoto; Murayama, Yuichi; Takao, Hiroyuki; Koivisto, Timo; Frösen, Juhana; Cebral, Juan R.,
2019.
Neurosurgical Focus.
47(1).
Available from: https://doi.org/10.3171/2019.4.FOCUS19145
-
Detmer, Felicitas J.; Fajardo-Jiménez, Daniel; Mut, Fernando; Juchler, Norman; Hirsch, Sven; Pereira, Vitor Mendes; Bijlenga, Philippe; Cebral, Juan R.,
2018.
Acta Neurochirurgica.
Available from: https://doi.org/10.1007/s00701-018-3712-8
-
Bijlenga, Philippe; Gondar, Renato; Schilling, Sabine; Morel, Sandrine; Hirsch, Sven; Cuony, Johanna; Corniola, Marco-Vincenzo; Perren, Fabienne; Rüfenacht, Daniel; Schaller, Karl,
2017.
PHASES score for the management of intracranial aneurysm.
Stroke: A Journal of Cerebral Circulation.
48(8), pp. 2105-2112.
Available from: https://doi.org/10.1161/STROKEAHA.117.017391
-
Daheim, Cornelia; Hirsch, Sven,
2015.
Emerging practices in foresight and their use in STI policy.
STI Policy Review.
6(2), pp. 24-53.
-
Delucchi, Matteo; Spinner, Georg; Furrer, Reinhard; Bijlenga, Philippe; Hirsch, Sven,
2024.
In:
8th International Conference on Computational and Mathematical Biomedical Engineering (CMBE), Arlington, VA, USA, 24-26 June 2024.
Computational & Mathematical Biomedical Engineering.
-
Delucchi, Matteo; Spinner, Georg R.; Bijlenga, Philippe; Morel, Sandrine; Hostettler, Isabel; Werring, David; Wostrack, Maria; Meyer, Bernhard; Bourcier, Romain; Lindgren, Antti; Bakker, Mark K.; Ruigrok, Ynte M.; Furrer, Reinhard; Hirsch, Sven,
2023.
In:
MDPI.
pp. 46-47.
Available from: https://doi.org/10.3390/ctn7040039
-
Delucchi, Matteo; Spinner, Georg Ralph; Scutari, Marco; Bijlenga, Philippe; Morel, Sandrine; Friedrich, Christoph M.; Hirsch, Sven,
2022.
Bayesian networks to disentangle the interplay of intracranial aneurysm rupture risk factors[paper].
In:
Nithiarasu, Perumal; Vergara, Christian, eds.,
CMBE 2022 : 7th International Conference on Computational & Mathematical Biomedical Engineering.
7th International Conference on Computational and Mathematical Biomedical Engineering (CMBE22), Milan, Italy, 27-29 June 2022.
Computational and Mathematical Biomedical Engineering.
pp. 22-25.
-
Dupuy, Nicolas; Juchler, Norman; Morel, Sandrine; Kwak, Brenda R.; Hirsch, Sven; Bijlenga, Philippe,
2022.
Exploring intracranial aneurysm instability markers to improve disease modeling[paper].
In:
Nithiarasu, Perumal; Vergara, Christian, eds.,
CMBE 2022 : 7th International Conference on Computational & Mathematical Biomedical Engineering.
7th International Conference on Computational and Mathematical Biomedical Engineering (CMBE22), Milan, Italy, 27-29 June 2022.
Computational and Mathematical Biomedical Engineering.
pp. 14-17.
Available from: https://doi.org/10.21256/zhaw-25387
-
Juchler, Norman; Bijlenga, Philippe; Hirsch, Sven,
2022.
Modeling the location-dependency of aneurysm shape : a morphometric comparative study[paper].
In:
Nithiarasu, Perumal; Vergara, Christian, eds.,
CMBE 2022 : 7th International Conference on Computational & Mathematical Biomedical Engineering.
7th International Conference on Computational and Mathematical Biomedical Engineering (CMBE22), Milan, Italy, 27-29 June 2022.
Computational & Mathematical Biomedical Engineering.
pp. 703-705.
Available from: https://doi.org/10.21256/zhaw-25388
-
Juchler, Norman; Bijlenga, Philippe; Hirsch, Sven,
2022.
The role of shape for aneurysm risk assessment[paper].
In:
Nithiarasu, Perumal; Vergara, Christian, eds.,
CMBE 2022 : 7th International Conference on Computational & Mathematical Biomedical Engineering.
7th International Conference on Computational and Mathematical Biomedical Engineering (CMBE22), Milan, Italy, 27-29 June 2022.
Computational & Mathematical Biomedical Engineering.
pp. 84-86.
Available from: https://doi.org/10.21256/zhaw-25386
-
Watanabe, Kazuhiro; Anzai, Hitomi; Juchler, Norman; Hirsch, Sven; Ohta, Makoto,
2020.
In:
International Mechanical Engineering Congress and Exposition : Volume 3 - biomedical and biotechnology engineering.
2019 International Mechanical Engineering Congress and Exposition, IMECE2019, Salt Lake City, Utah, USA, 11-14 November 2019.
The American Society of Mechanical Engineers.
Available from: https://doi.org/10.1115/IMECE2019-11125
-
Juchler, Norman; Schilling, Sabine; Bijlenga, Philippe; Rüfenacht, Daniel; Kurtcuoglu, Vartan; Hirsch, Sven,
2019.
Identification of clinically relevant characteristics of intracranial aneurysm morphology[poster].
In:
1. Digital Health Lab Day (Life in Numbers 5), Wädenswil, 3. October 2019.
ZHAW Zürcher Hochschule für Angewandte Wissenschaften.
-
Juchler, Norman; Schilling, Sabine; Bijlenga, Philippe; Kurtcuoglu, Vartan; Hirsch, Sven,
2017.
Measuring the perceived morphological complexity of intracranial aneurysms[poster].
In:
Abstract Book, 3rd International SystemsX.ch Conference on Systems Biology.
SystemsX.ch Conference, Zurich, 4-7 September 2017.
pp. 160.
Available from: https://doi.org/10.3929/ethz-b-000176201
-
Juchler, Norman; Schilling, Sabine; Vartan, Kurtcuoglu; Hirsch, Sven,
2016.
What's ugly? : shape-based analysis of intracranial aneurysms[poster].
In:
Latsis Symposium 2016 : Personalized Medicine, Zurich, 27-29 June 2016.
-
Juchler, Norman; Ebnöther, Ueli; Schilling, Sabine; Hirsch, Sven; Kurtcuoglu, Vartan,
2015.
On the utility of 3D Zernike Moment Invariants to assess aneurysm disease status[poster].
In:
All SystemsX.ch Day, Bern, 15 September 2015.
-
Hirsch, Sven; Egger, Julian; Wanke, Isabel; Kulcsar, Zsolt; Rüfenacht, Daniel,
2013.
In:
CMBE13 : 3rd International Conference on Computational & Mathematical Biomedical Engineering.
CMBE 2013, Hong Kong, , 16-18 December 2013.
Hong Kong:
City University of Hong Kong.
pp. 107-110.
-
Bührer, Lea; Bijlenga, Philippe; Delucchi, Matteo; Furrer, Reinhard; Spinner, Georg; Hirsch, Sven,
2024.
Modelling the burden of disease of intracanial aneurysms[poster].
In:
6th Digital Health Lab Day, Winterthur, Switzerland, 3 September 2024.
ZHAW Zurich University of Applied Sciences.
Available from: https://doi.org/10.21256/zhaw-33654
-
Gerber, Nicole; Fieseler, Lars; Hirsch, Sven; Neutsch, Lukas; Papadopoulou, Athina; Smits, Theo,
2022.
Clinicum.
2022(6), pp. 80-81.
Available from: https://doi.org/10.21256/zhaw-26376
-
Bakker, Mark K.; van der Spek, Rick A. A.; van Rheenen, Wouter; Morel, Sandrine; Bourcier, Romain; Hostettler, Isabel C.; Alg, Varinder S.; van Eijk, Kristel R.; Koido, Masaru; Akiyama, Masato; Terao, Chikashi; Matsuda, Koichi; Walters, Robin G.; Lin, Kuang; Li, Liming; Millwood, Iona Y.; Chen, Zhengming; Rouleau, Guy A.; Zhou, Sirui; Rannikmäe, Kristiina; Sudlow, Cathie L. M.; Houlden, Henry; van den Berg, Leonard H.; Dina, Christian; Naggara, Olivier; Gentric, Jean-Christophe; Shotar, Eimad; Eugène, François; Desal, Hubert; Winsvold, Bendik S.; Børte, Sigrid; Johnsen, Marianne Bakke; Brumpton, Ben M.; Sandvei, Marie Søfteland; Willer, Cristen J.; Hveem, Kristian; Zwart, John-Anker; Verschuren, W. M. Monique; Friedrich, Christoph M.; Hirsch, Sven; Schilling, Sabine; Dauvillier, Jérôme; Martin, Olivier; Jones, Gregory T.; Bown, Matthew J.; Ko, Nerissa U.; Kim, Helen; Coleman, Jonathan R. I.; Breen, Gerome; Zaroff, Jonathan G.; Klijn, Catharina J. M.; Malik, Rainer; Dichgans, Martin; Sargurupremraj, Muralidharan; Tatlisumak, Turgut; Amouyel, Philippe; Debette, Stéphanie; Rinkel, Gabriel J. E.; Worrall, Bradford B.; Pera, Joanna; Slowik, Agnieszka; Gaál-Paavola, Emília I.; Niemelä, Mika; Jääskeläinen, Juha E.; von Und Zu Fraunberg, Mikael; Lindgren, Antti; Broderick, Joseph P.; Werring, David J.; Woo, Daniel; Redon, Richard; Bijlenga, Philippe; Kamatani, Yoichiro; Veldink, Jan H.; Ruigrok, Ynte M.,
2021.
Nature Genetics.
53(2), pp. 254.
Available from: https://doi.org/10.1038/s41588-020-00760-4
-
Bührer, Lea; Bakker, Mark; Bijlenga, Philippe; Furrer, Reinhard; Hirsch, Sven; Morel, Sandrine; Spinner, Georg,
2025.
In:
32nd Workshop of the International Stroke Genomics Consortium, Gothenburg, Sweden, 14-16 May 2025.
-
Melloh, Markus; Hirsch, Sven,
2019.
How universities can lead the transformation to digital health.
In:
Digital Health Conclave, Bangalore, India, 8 April 2019.
-
Hirsch, Sven; Juchler, Norman,
2019.
In:
1. Digital Health Lab Day (Life in Numbers 5), Wädenswil, 3. October 2019.
-
Watanabe, Kazuhiro; Anzai, Hitomi; Juchler, Norman; Hirsch, Sven; Bijlenga, Philippe; Ohta, Makoto,
2018.
Effect of input image representation for results of neural network to detect cerebral aneurysms.
In:
31st Bioengineering Conference / 2018 Annual Meeting of BED/JSME, Koriyama, Japan, 14-15 December 2018.
-
Hirsch, Sven; Juchler, Norman; Schilling, Sabine; Bijlenga, Philippe; Rüfenacht, Daniel,
2018.
Using machine learning to identify shape biomarkers in intracranial aneurysm.
In:
Life Science Zurich Impact, Zürich, 22 January 2018.
-
Hirsch, Sven; Juchler, Norman; Schilling, Sabine; Bijlenga, Philippe; Rüfenacht, Daniel,
2017.
Big Data : machine learning to identify shape biomarkers in intracranial aneurysm.
In:
Annual Meeting of the Swiss Society for Biomedical Engineering (SSBE), Winterthur, 30 August 2017.
-
Juchler, Norman; Schilling, Sabine; Wanke, Isabel; Rüfenacht, Daniel; Bijlenga, Philippe; Kurtcuoglu, Vartan; Hirsch, Sven,
2017.
Using shape descriptors to categorize intracranial aneurysms.
In:
CMBE17 : 5th International Conference on Computational and Mathematical Biomedical Engineering.
CMBE 2017, Pittsburgh PA, USA, 10-12 April 2017.
-
Anzai, Hitomi; Juchler, Norman; Ohta, Makoto; Hirsch, Sven; Rüfenacht, Daniel A.; Wanke, Isabel,
2017.
Where does CFD identify lesion instability in small aneurysms?.
In:
CMBE17 : 5th International Conference on Computational and Mathematical Biomedical Engineering.
CMBE 2017, Pittsburgh PA, USA, 10-12 April 2017.
-
Juchler, Norman; Schilling, Sabine; Wanke, Isabel; Rüfenacht, Daniel; Bijlenga, Philippe; Kurtcuoglu, Vartan; Hirsch, Sven,
2016.
Shape-based modeling of aneurysmal disease status.
In:
ECCOMAS Congress 2016, Heraklion, Greece, 5-10 June 2016.
-
Neufeld, Esra; Wissmann, Phillipp; Szczerba, Dominik; Teixeira, Frederico; Hirsch, Sven; Kuster, Niels,
2015.
In:
9th European Solid Mechanics Conference (ESMC), Madrid, Spain, 6-10 July 2015.
Research data
Juchler, Norman; Bijlenga, Philippe; Hirsch, Sven, 2022. AneuX morphology database. Zenodo. Available from: https://doi.org/10.5281/zenodo.6678442