Dr. Mathias Weyland

ZHAW School of Engineering
Forschungsschwerpunkt Applied Complex Systems Science
Technikumstrasse 9
8400 Winterthur

+41 (0) 58 934 64 58
mathias.weyland@zhaw.ch

Projects

Next Generation 3D Tissue Models: Bio-Hybrid Hierarchical Organoid-Synthetic Tissues (Bio-HhOST) Comprised of Live and Artificial Cells. / Deputy project leader / Project ongoing
PHARAO / Team member / Project ongoing
Neurological ICU Data / Team member / Project completed
Extension SARS-CoV-2 Intervention modelling / Team member / Project completed
Decision support for pandemics / Team member / Project completed
SARS-CoV2 Modeling of Interventions on the Dynamics of the Pandemics / Deputy project leader / Project completed
Epidemiologische Multiskalensimulation zur Analyse der Übertragungsmechanismen in der COVID-19 Pandemie / Team member / Project completed
ACDC – Artificial Cells with Distributed Cores to Decipher Protein Function / Team member / Project completed
OptiRad / Team member / Project completed
Thermal Dosimetric Concept for Evaluating Synergistic Effect of Combined Hyperthermia-Radiotherapy (RT-HT) / Team member / Project completed
Phantom- and Model-based Optimisation of Medical Imaging Modalities / Team member / Project completed

Publications

Articles in scientific journal, peer-reviewed

Nytko, K. J.; Weyland, M.; Dressel-Böhm, S.; Scheidegger, S.; Salvermoser, L.; Werner, C.; Stangl, S.; Carpinteiro, A. C.; Alkotub, B.; Multhoff, G.; Bodis, S.; Rohrer Bley, C.,

2023.

Extracellular heat shock protein 70 levels in tumour-bearing dogs and cats treated with radiation therapy and hyperthermia.

Veterinary and Comparative Oncology.

21(4), pp. 605-615.

Available from: https://doi.org/10.1111/vco.12923
Fuchs, Daniel; Rohrer Bley, Carla; Morandi, Luca; Tonon, Caterina; Weyland, Mathias S.; Nytko, Katarzyna J.,

2023.

Triple combination of lomustine, temozolomide and irradiation reduces canine glioma cell survival in vitro.

Veterinary Medicine and Science.

9(4), pp. 1573-1583.

Available from: https://doi.org/10.1002/vms3.1181
Sommer, Christian; Özden, Ismail; Weyland, Mathias S.; Duran, Carolina; Lutters, Gerd; Scheidegger, Stephan,

2022.

Feasibility of a method for low contrast CT image quality assessment using difference detail curves for abdominal scans.

Zeitschrift für Medizinische Physik.

32(2), pp. 209-217.

Available from: https://doi.org/10.1016/j.zemedi.2022.01.001
Riesterer, Oliver; Ademaj, Adela; Puric, Emsad; Eberle, Brigitte; Beck, Marcus; Gomez, Silvia; Marder, Dietmar; Oberacker, Eva; Rogers, Susanne; Hälg, Roger A.; Kern, Thomas; Schwenne, Sonja; Stein, Jürgen; Stutz, Emanuel; Timm, Olaf; Zschaeck, Sebastian; Weyland, Mathias S.; Veltsista, Paraskevi D.; Wyler, Stephen; Wust, Peter; Scheidegger, Stephan; Bodis, Stephan; Ghadjar, Pirus,

2022.

Tetramodal therapy with transurethral resection followed by chemoradiation in combination with hyperthermia for muscle-invasive bladder cancer : early results of a multicenter phase IIB study.

International Journal of Hyperthermia.

39(1), pp. 1078-1087.

Available from: https://doi.org/10.1080/02656736.2022.2109763
Weyland, Mathias S.; Thumser-Henner, Pauline; Nytko, Katarzyna J.; Rohrer Bley, Carla; Ulzega, Simone; Petri-Fink, Alke; Lattuada, Marco; Füchslin, Rudolf Marcel; Scheidegger, Stephan,

2020.

Holistic view on cell survival and DNA damage : how model-based data analysis supports exploration of dynamics in biological systems.

Computational and Mathematical Methods in Medicine.

2020.

Available from: https://doi.org/10.1155/2020/5972594
Marconato, Laura; Weyland, Mathias S.; Tresch, Nina; Rossi, Federica; Leone, Vito; Rohrer Bley, Carla,

2020.

Toxicity and outcome in cats with oral squamous cell carcinoma after accelerated hypofractionated radiotherapy and concurrent systemic treatment.

Veterinary and Comparative Oncology.

18(3), pp. 362-369.

Available from: https://doi.org/10.1111/vco.12557
Cueni, Claudia; Nytko, Katarzyna J.; Thumser-Henner, Pauline; Weyland, Mathias S.; Rohrer Bley, Carla,

2020.

Methadone does not potentiate the effect of doxorubicin in canine tumour cell lines.

Veterinary Medicine and Science.

6(3), pp. 283-289.

Available from: https://doi.org/10.1002/vms3.266
Nytko, Katarzyna J.; Thumser-Henner, Pauline; Russo, Giancarlo; Weyland, Mathias S.; Rohrer Bley, Carla,

2020.

Role of HSP70 in response to (thermo)radiotherapy : analysis of gene expression in canine osteosarcoma cells by RNA-seq.

Scientific Reports.

10(1), pp. 12779.

Available from: https://doi.org/10.1038/s41598-020-69619-2
Meier, Valeria S.; Beatrice, Laura; Turek, Michelle; Poirier, Valerie J.; Cancedda, Simona; Stiborova, Katerina; Körner, Maximilian; Marconato, Laura; Weyland, Mathias S.; Rohrer Bley, Carla,

2019.

Outcome and failure patterns of localized sinonasal lymphoma in cats treated with first-line single-modality radiation therapy : a retrospective study.

Veterinary and Comparative Oncology.

17(4), pp. 528-536.

Available from: https://doi.org/10.1111/vco.12517
Pyka, Miriam; Eschle, Patrik; Sommer, Christian; Weyland, Mathias S.; Kubik, Rahel; Scheidegger, Stephan,

2018.

Effect of thyroid shielding during mammography : measurements on phantom and patient as well as estimation with Monte Carlo simulation.

European Radiology Experimental.

2(14).

Available from: https://doi.org/10.1186/s41747-018-0042-9
Schulz, Nadine; Chaachouay, Hassan; Nytko, Katarzyna J.; Weyland, Mathias S.; Roos, Malgorzata; Füchslin, Rudolf Marcel; Guscetti, Franco; Scheidegger, Stephan; Rohrer Bley, Carla,

2017.

Dynamic in vivo profiling of DNA damage and repair after radiotherapy using canine patients as a model.

International Journal of Molecular Sciences.

18(6/1176).

Available from: https://doi.org/10.3390/ijms18061176
Dressel, S.; Gosselin, M.-C.; Capstick, M. H.; Carrasco, E.; Weyland, Mathias; Scheidegger, Stephan; Neufeld, E.; Kuster, N.; Bodis, S.; Rohrer Bley, C.,

2017.

Novel hyperthermia applicator system allows adaptive treatment planning : preliminary clinical results in tumour-bearing animals.

Veterinary and Comparative Oncology.

16(2), pp. 202-213.

Available from: https://doi.org/10.1111/vco.12340
Füchslin, Rudolf Marcel; Dumont, Elisabeth; Flumini, Dandolo; Fuchs, Hans Ulrich; Hauser, Helmut; Jaeger, Christian; Scheidegger, Stephan; Schönenberger-Deuel, Johanna; Lichtensteiger, Lukas; Luchsinger, Rolf H.; Weyland, Mathias,

2014.

Morphological control : a design principle for applications in space science.

Journal of the British Interplanetary Society.

67, pp. 305-313.

Available from: http://adsabs.harvard.edu/abs/2014JBIS...67..305F
Weyland, Mathias S.; Fellermann, Harold; Hadorn, Maik; Sorek, Daniel; Lancet, Doron; Rasmussen, Steen; Füchslin, Rudolf Marcel,

2013.

The MATCHIT automaton : exploiting compartmentalization for the synthesis of branched polymers.

Computational and Mathematical Methods in Medicine.

2013(467428).

Available from: https://doi.org/10.1155/2013/467428

Conference contributions, peer-reviewed

Weyland, Mathias S.; Flumini, Dandolo; Schneider, Johannes J.; Faggian, Alessia; Patiño Diaz, Aitor; Füchslin, Rudolf Marcel,

2023.

A chemical compiler for the synthesis of branched oligomers on standardized chemical reaction structures [paper].

In:

ALIFE 2023: Ghost in the Machine : Proceedings of the 2023 Artificial Life Conference.

International Conference on Artificial Life (ALIFE), Sapporo, Japan, 24-28 July 2023.

Cambridge:

MIT Press.

pp. 105.

Available from: https://doi.org/10.1162/isal_a_00648
Schneider, Johannes Josef; Faggian, Alessia; Jamieson, William David; Weyland, Mathias Sebastian; Li, Jin; Castell, Oliver; Matuttis, Hans-Georg; Barrow, David Anthony; Patiño Diaz, Aitor; Sanahuja, Lorena Cebolla; Holler, Silvia; Casiraghi, Federica; Hanczyc, Martin Michael; Flumini, Dandolo; Eggenberger Hotz, Peter; Füchslin, Rudolf Marcel,

2023.

Artificial chemistry performed in an agglomeration of droplets with restricted molecule transfer [paper].

In:

De Stefano, Claudio; Fontanella, Francesco; Vanneschi, Leonardo, eds.,

Artificial Life and Evolutionary Computation.

XVI Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Gaeta, Italy, 14-16 September 2022.

Cham:

Springer.

pp. 107-118.

Communications in Computer and Information Science ; 1780.

Available from: https://doi.org/10.1007/978-3-031-31183-3_9
Matuttis, Hans-Georg; Schneider, Johannes Josef; Li, Jin; Barrow, David Anthony; Faggian, Alessia; Patiño Diaz, Aitor; Holler, Silvia; Casiraghi, Federica; Sanahuja, Lorena Cebolla; Hanczyc, Martin Michael; Weyland, Mathias Sebastian; Flumini, Dandolo; Eggenberger Hotz, Peter; Dimitriou, Pantelitsa; Jamieson, William David; Castell, Oliver; Füchslin, Rudolf Marcel,

2023.

Computational investigation of the clustering of droplets in widening pipe geometries [paper].

In:

De Stefano, Claudio; Fontanella, Francesco; Vanneschi, Leonardo, eds.,

Artificial Life and Evolutionary Computation.

XVI Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Gaeta, Italy, 14-16 September 2022.

Cham:

Springer.

pp. 82-93.

Communications in Computer and Information Science ; 1780.

Available from: https://doi.org/10.1007/978-3-031-31183-3_7
Schneider, Johannes Josef; Faggian, Alessia; Patiño Diaz, Aitor; Li, Jin; Holler, Silvia; Casiraghi, Federica; Sanahuja, Lorena Cebolla; Matuttis, Hans-Georg; Hanczyc, Martin Michael; Barrow, David Anthony; Weyland, Mathias Sebastian; Flumini, Dandolo; Eggenberger Hotz, Peter; Dimitriou, Pantelitsa; Jamieson, William David; Castell, Oliver; Eschle, Patrik; Füchslin, Rudolf Marcel,

2023.

Network creation during agglomeration processes of polydisperse and monodisperse systems of droplets [paper].

In:

De Stefano, Claudio; Fontanella, Francesco; Vanneschi, Leonardo, eds.,

Artificial Life and Evolutionary Computation.

XVI Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Gaeta, Italy, 14-16 September 2022.

Cham:

Springer.

pp. 94-106.

Communications in Computer and Information Science ; 1780.

Available from: https://doi.org/10.1007/978-3-031-31183-3_8
Füchslin, Rudolf Marcel; Ambühl, Jacques; Faggian, Alessia; Fellermann, Harold M.; Flumini, Dandolo; Geller, Armando; Hanczyc, Martin M.; Klinkert, Andreas; Krütli, Pius; Matuttis, Hans-Georg; Ott, Thomas; Scheidegger, Stephan; Schmid, Gary Bruno; Smieszek, Timo; Schneider, Johannes J.; Steiner, Albert; Weyland, Mathias S.,

2023.

Ethical aspects of computational modelling in science, decision support and communication [paper].

In:

Artificial Life and Evolutionary Computation.

XV Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Winterthur, Switzerland, 15-17 September 2021.

Cham:

Springer.

Communications in Computer and Information Science ; 1722.

Available from: https://doi.org/10.1007/978-3-031-23929-8_24
Schneider, Johannes Josef; Weyland, Mathias Sebastian; Flumini, Dandolo; Füchslin, Rudolf Marcel,

2023.

Exploring the three-dimensional arrangement of droplets [paper].

In:

Artificial Life and Evolutionary Computation.

XV Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Winterthur, Switzerland, 15-17 September 2021.

Cham:

Springer.

Communications in Computer and Information Science ; 1722.

Available from: https://doi.org/10.1007/978-3-031-23929-8_6
Schneider, Johannes Josef; Barrow, David Anthony; Li, Jin; Weyland, Mathias Sebastian; Flumini, Dandolo; Eggenberger Hotz, Peter; Füchslin, Rudolf Marcel,

2023.

Geometric restrictions to the agglomeration of spherical particles [paper].

In:

Artificial Life and Evolutionary Computation.

XV Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Winterthur, Switzerland, 15-17 September 2021.

Cham:

Springer.

Communications in Computer and Information Science ; 1722.

Available from: https://doi.org/10.1007/978-3-031-23929-8_7
Schneider, Johannes Josef; Faggian, Alessia; Matuttis, Hans-Georg; Barrow, David Anthony; Li, Jin; Holler, Silvia; Casiraghi, Federica; Cebolla Sanahuja, Lorena; Hanczyc, Martin Michael; Eschle, Patrik; Weyland, Mathias Sebastian; Flumini, Dandolo; Eggenberger Hotz, Peter; Füchslin, Rudolf Marcel,

2023.

Obstacles on the pathway towards chemical programmability using agglomerations of droplets [paper].

In:

Artificial Life and Evolutionary Computation.

XV Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Winterthur, Switzerland, 15-17 September 2021.

Cham:

Springer.

Communications in Computer and Information Science ; 1722.

Available from: https://doi.org/10.1007/978-3-031-23929-8_4
Schneider, Johannes Josef; Weyland, Mathias Sebastian; Flumini, Dandolo; Füchslin, Rudolf Marcel, eds.,

2023.

Artificial Life and Evolutionary Computation : 15th Italian Workshop, WIVACE 2021, Winterthur, Switzerland, September 15–17, 2021.

XV International Workshop on Artificial Life and Evolutionary Computation (WIVACE), Winterthur, Switzerland, 15-17 September 2021.

Cham:

Springer.

Communications in Computer and Information Science ; 1722.

ISBN 978-3-031-23928-1.

Available from: https://doi.org/10.1007/978-3-031-23929-8
Chehda Moreno, Nora; Weyland, Mathias; Smieszek, Timo; Füchslin, Rudolf Marcel; Krütli, Pius; Schneider, Johannes Josef; Scheidegger, Stephan,

2021.

Interpreting difference measures for social contact matrices : impact on the pandemic dynamics [poster].

In:

8th International Conference on Infectious Disease Dynamics (Epidemics8), online, 30 November - 3 December 2021.
Schneider, Johannes Josef; Weyland, Mathias Sebastian; Flumini, Dandolo; Füchslin, Rudolf Marcel,

2020.

Investigating three-dimensional arrangements of droplets [paper].

In:

Cicirelli, Franco; Guerrieri, Antonio; Pizzuti, Clara; Socievole, Annalisa; Spezzano, Giandomenico; Vinci, Andrea, eds.,

Artificial Life and Evolutionary Computation.

XIV Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Rende, Italy, 18-20 September 2019.

Cham:

Springer.

pp. 171-184.

Communications in Computer and Information Science ; 1200.

Available from: https://doi.org/10.1007/978-3-030-45016-8_17
Schneider, Johannes Josef; Weyland, Mathias Sebastian; Flumini, Dandolo; Matuttis, Hans-Georg; Morgenstern, Ingo; Füchslin, Rudolf Marcel,

2020.

Studying and simulating the three-dimensional arrangement of droplets [paper].

In:

Cicirelli, Franco; Guerrieri, Antonio; Pizzuti, Clara; Socievole, Annalisa; Spezzano, Giandomenico; Vinci, Andrea, eds.,

Artificial Life and Evolutionary Computation.

XIV Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Rende, Italy, 18-20 September 2019.

Cham:

Springer.

Communications in Computer and Information Science ; 1200.

Available from: https://doi.org/10.1007/978-3-030-45016-8_16
Flumini, Dandolo; Weyland, Mathias S.; Schneider, Johannes J.; Fellermann, Harold; Füchslin, Rudolf M.,

2020.

Towards programmable chemistries [paper].

In:

Cicirelli, Franco; Guerrieri, Antonio; Pizzuti, Clara; Socievole, Annalisa; Spezzano, Giandomenico; Vinci, Andrea, eds.,

Artificial Life and Evolutionary Computation.

XIV Italian Workshop on Artificial Life and Evolutionary Computation (WIVACE), Rende, Italy, 18-20 September 2019.

Springer.

Communications in Computer and Information Science ; 1200.

Available from: https://doi.org/10.1007/978-3-030-45016-8_15
Schneider, Johannes Josef; Weyland, Mathias; Flumini, Dandolo; Füchslin, Rudolf Marcel,

2019.

Simulation of a microfluidic system of droplets [poster].

In:

Joint Annual Meeting of the Swiss Physical Society and the Austrian Physical Society, Zurich, 26-30 August 2019.
Weyland, Mathias; Thumser-Henner, Pauline; Rohrer Bley, Carla; Ulzega, Simone; Petri-Fink, Alke; Lattuada, Marco; Scheidegger, Stephan; Füchslin, Rudolf Marcel,

2019.

Dynamic DNA damage and repair modelling : bridging the gap between experimental damage readout and model structure [paper].

In:

Cagnoni, Stefano; Mordonini, Monica; Pecori, Riccardo; Roli, Andrea; Villani, Marco, eds.,

Artificial Life and Evolutionary Computation.

XIII International Workshop on Artificial Life and Evolutionary Computation (WIVACE), Parma, Italy, 10-12 September 2018.

Cham:

Springer.

pp. 127-137.

Communications in Computer and Information Science ; 900.

Available from: https://doi.org/10.1007/978-3-030-21733-4_10

Other publications

Füchslin, Rudolf Marcel; Krütli, Pius; Ott, Thomas; Scheidegger, Stephan; Schneider, Johannes Josef; Seric, Marko; Smieszek, Timo; Weyland, Mathias S.,

2022.

Minimal models for spatially resolved population dynamics : applications to coexistence in multi – trait models [paper].

In:

ALIFE 2022: The 2022 Conference on Artificial Life.

International Conference on Artificial Life (ALIFE), online, 18-22 July 2022.

Cambridge:

MIT Press.

pp. 75.

Available from: https://doi.org/10.1162/isal_a_00504
Schneider, Johannes Josef; Faggian, Alessia; Holler, Silvia; Casiraghi, Federica; Li, Jin; Sanahuja, Lorena Cebolla; Matuttis, Hans-Georg; Hanczyc, Martin Michael; Barrow, David Anthony; Weyland, Mathias Sebastian; Flumini, Dandolo; Eggenberger Hotz, Peter; Eschle, Patrik; Patiño Diaz, Aitor; Füchslin, Rudolf Marcel,

2022.

Paths in a network of polydisperse spherical droplets [paper].

In:

ALIFE 2022: The 2022 Conference on Artificial Life.

International Conference on Artificial Life (ALIFE), online, 18-22 July 2022.

Cambridge:

MIT Press.

pp. 23.

Available from: https://doi.org/10.1162/isal_a_00502
Weyland, Mathias S.; Flumini, Dandolo; Schneider, Johannes J.; Füchslin, Rudolf M.,

2020.

A compiler framework to derive microfluidic platforms for manufacturing hierarchical, compartmentalized structures that maximize yield of chemical reactions [paper].

In:

ALIFE 2020: The 2020 Conference on Artificial Life.

International Conference on Artificial Life (ALIFE), online, 13-18 July 2020.

Cambridge:

MIT Press.

pp. 602-604.

Available from: https://doi.org/10.1162/isal_a_00303
Weyland, Mathias; Eberle, B; Dressel, S; Timm, O; Puric, E; Rohrer Bley, C; Scheidegger, Stephan,

2017.

Comparison of thermal dose concepts in human and animal patients [paper].

In:

ESHO Annual Meeting.

31th Annual Meeting, European Society for Hyperthermic Oncology (ESHO 2017), Athens, Greece, 21-23 June 2017.

pp. 87-88.

Oral conference contributions and abstracts

Schneider, Johannes Josef; Barrow, David Anthony; Li, Jin; Weyland, Mathias; Flumini, Dandolo; Eggenberger Hotz, Peter; Füchslin, Rudolf Marcel,

2023.

Bidisperse extension of the kissing number problem.

In:

28th International Conference on Statistical Physics (Statphys28), Tokyo, Japan, 7-11 August 2023.
Sommer, Christian; Özden, Ismail; Weyland, Mathias; Duran, Carolina; Lutters, Gerd; Scheidegger, Stephan,

2021.

Using difference detail curves to assess image quality of low contrast abdominal CT scans.

In:

3rd European Congress of Medical Physics (ECMP), virtual, 16 June - 31 December 2021.
Schneider, Johannes Josef; Faggian, Alessia; Holler, Silvia; Casiraghi, Federica; Li, Jin; Cebolla Sanahuja, Lorena; Matuttis, Hans-Georg; Hanczyc, Martin Michael; Barrow, David Anthony; Weyland, Mathias Sebastian; Flumini, Dandolo; Eggenberger Hotz, Peter; Füchslin, Rudolf Marcel,

2021.

Influence of the geometry on the agglomeration of a polydisperse binary system of spherical particles.

In:

International Conference on Artificial Life (ALIFE), online, 19-23 July 2021.

Available from: https://www.youtube.com/watch?v=2uSgimAHU4I
Füchslin, Rudolf Marcel; Scheidegger, Stephan; Flumini, Dandolo; Schneider, Johannes Josef; Weyland, Mathias,

2019.

Morphological computation and control in medicine and related sciences.

In:

BioDynaMo, Zurich, 2-3 December 2019.
Flumini, Dandolo; Weyland, Mathias,

2019.

Steps towards programmable chemistries.

In:

XIV International Workshop on Artificial Life and Evolutionary Computation (WIVACE), Rende, Italy, 18-20 September 2019.
Schneider, Johannes Josef; Weyland, Mathias; Flumini, Dandolo; Füchslin, Rudolf Marcel,

2019.

Exploring the three-dimensional arrangement of droplets.

In:

XIV International Workshop on Artificial Life and Evolutionary Computation (WIVACE), Rende, Italy, 18-20 September 2019.
Weyland, Mathias; Thumser-Henner, Pauline; Rohrer Bley, Carla; Ulzega, Simone; Petri-Fink, Alke; Lattuada, Marco; Scheidegger, Stephan; Füchslin, Rudolf Marcel,

2018.

Dynamic DNA damage and repair modeling : bridging the gap between experimental damage readout and model structure.

In:

XIII International Workshop on Artificial Life and Evolutionary Computation (WIVACE), Parma, Italy, 10-12 September 2018.
Weyland, Mathias; Thumser-Henner, Pauline; Nytko, KJ; Rohrer Bley, Carla; Scheidegger, Stephan,

2018.

Extracting information about cellular repair processes after hyperthermia – radiotherapy by model-based data analysis : ambiguities in survival prediction as a challenge?.

In:

32nd Annual Meeting of the European Society for Hyperthermic Oncology, Berlin, Germany, 16-19 May 2018.

Springer.

pp. 503.

Available from: https://doi.org/10.1007/s00066-018-1295-1

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