Dr. Misha Teale

Work at ZHAW

Position

Research Associate

Network

ORCID digital identifier

ORCID ID: 0000-0003-0599-4115

Projects

• Biological characterization of a novel single-use bioreactor through the cultivation of pluripotent stem cells under various conditions / Deputy project leader / completed
• Stem cell expansion process with microcarriers / Team member / completed
• Scale-up of a scaffold-based cultivation process for the production of clean meat / Deputy project leader / completed
• Biological characterization of a novel single-use bioreactor through the cultivation of pluripotent stem cells on microcarriers / Deputy project leader / completed
• Evaluation Perfusion / Team member / completed
• Scalable Stem Cell Platform for the production of iPSCs / Deputy project leader / completed
• A Kuhner TOM system for process developments with stem cells (Kuhner TOM StemCell) / Team member / completed
• Process development for COVID-19 VLP vaccine production / Team member / completed
• Growth performance studies / Deputy project leader / completed
• Microbiome therapeutics / Team member / completed
• Organ-on-a-Chip / Deputy project leader / completed

Publications

• Schneider, Samuel; Gopalakrishnan, Abiram; Teale, Misha; Eibl, Regine,

  2025.

  Cell retention in scalable, perfusion-based mesenchymal stem cell expansion processes : a proof of concept.

  Frontiers in Bioengineering and Biotechnology.

  13(1611703).

  Available from: https://doi.org/10.3389/fbioe.2025.1611703

• Schneider, Samuel; Teale, Misha; Seidel, Stefan; Krasenbrink, Jürgen; Poggel, Martin; Eibl, Dieter; Sousa, Marcos F. Q.; Eibl, Regine,

  2025.

  Expansion of induced pluripotent stem cells under consideration of bioengineering aspects : part 1.

  Applied Microbiology and Biotechnology.

  109(37).

  Available from: https://doi.org/10.1007/s00253-024-13372-3

• Teale, Misha; Schneider, Samuel; Seidel, Stefan; Krasenbrink, Jürgen; Poggel, Martin; Eibl, Dieter; Sousa, Marcos F.Q.; Eibl, Regine,

  2025.

  Expansion of induced pluripotent stem cells under consideration of bioengineering aspects : part 2.

  Applied Microbiology and Biotechnology.

  109(38).

  Available from: https://doi.org/10.1007/s00253-024-13373-2

• Teale, Misha Alexander; Schneider, Samuel Lukas; Eibl, Dieter; Eibl-Schindler, Regine,

  2024.

  Process intensification in human pluripotent stem cell expansion with microcarriers.

  Processes.

  12(3), pp. 426.

  Available from: https://doi.org/10.3390/pr12030426

• Teale, Misha A.; Schneider, Samuel; Eibl, Dieter; van den Bos, Christian; Neubauer, Peter; Eibl, Regine,

  2023.

  Mesenchymal and induced pluripotent stem cell-based therapeutics : a comparison.

  Applied Microbiology and Biotechnology.

  107(14), pp. 4429-4445.

  Available from: https://doi.org/10.1007/s00253-023-12583-4

• Teale, Misha; Jossen, Valentin; Eibl, Dieter; Eibl-Schindler, Regine,

  2021.

  Chemically defined, xeno-free expansion of human mesenchymal stem cells (hMSCs) on benchtop-scale using a stirred single-use bioreactor.

  In:

  Turksen, Kursad, ed.,

  Bioreactors in Stem Cell Biology : Methods and Protocols.

  New York, NY:

  Humana.

  pp. 83-111.

  Methods in Molecular Biology ; 2436.

  Available from: https://doi.org/10.1007/7651_2021_426

• Müller, Jan; Teale, Misha; Steiner, Sandra; Junne, Stefan; Neubauer, Peter; Eibl, Dieter; Eibl-Schindler, Regine,

  2021.

  Intensified and continuous mAb production with single-use systems.

  In:

  Pörtner, Ralf, ed.,

  Cell Culture Engineering and Technology.

  Cham:

  Springer.

  pp. 401-429.

  Cell Engineering ; 10.

  Available from: https://doi.org/10.1007/978-3-030-79871-0_13

• Bayer, Marcus; Castan, Andreas; Eibl, Regine; Eibl, Dieter; Eisenkrätzer, Detlef; Fritz, Christina; Glaser, Robert; Glenz, Martin; Greller, Gerhard; Hug, Michelle; Kleebank, Sebastian; Kampmann, Markus; Krättli, Martin; Manser, Britta; Matuszczyk, Jens; Ottinger, Melanie; Schleper, Stefan; Schreiber, Marko; Seidel, Stefan; Selzer, Sebastian; Tanner, Markus; Teale, Misha; Tiemann, Karin,

  2020.

  Technical state-of-the-art and risk analysis on single-use equipment in continuous processing steps.

  Frankfurt am Main:

  DECHEMA, Gesellschaft für Chemische Technik und Biotechnologie e.V..

  ISBN 978-3-89746-226-7.

  Available from: https://doi.org/10.21256/zhaw-26357

• Rossi, Lia; Schirmer, Cedric; Teale, Misha; Kurt, Fabienne; Rosenthal, Florian; Eibl, Dieter,

  2019.

  Proof of concept study for cultivation of strict anaerobes in a single-use wave-mixed bioreactor[poster].

  In:

  BioTech 2019 : Biopharmaceutical Manufacturing and Single-Use Technologies, Wädenswil, Switzerland, 2-4 July 2019.

  ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

• Nosswitz, Michael; Teale, Misha; Mathes, Stephanie; Venturato, Andrea; Gasser, Angelines,

  2019.

  Evaluation of anodized surfaces designed for improved soft tissue integration.

  Foundation for Oral Rehabilitation.

  Available from: https://www.for.org/en/learn/scientific-article/evaluation-anodized-surfaces-improved-soft-tissue-integration

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