Dr. Susanne Kern

Projects

• Development of a depth filter for PFAS removal / Deputy project leader / ongoing
• Sustainable hyaluronic acid production from lignocellulosic biomass / Team member / ongoing
• Development of analytical methods specific to aquaculture / Project leader / completed
• Dynamik Knowledge Platform / Team member / completed

Publications

Articles in scientific journal, peer-reviewed

• Mendo Diaz, O., Tell, A., Hangartner, S., Hutter, J., Stalder, U., Friedl, H., Buser, A. M., Kern, S., Bigler, L., Bleiner, D., & Heeb, N. V. (2025). Determination of chlorinated paraffins and olefins in plastic consumer products of the Swiss market. Chemosphere, 374(144239). https://doi.org/10.1016/j.chemosphere.2025.144239
• Mathis, F., Iten, S., Knobloch, M., Fleischmann, T., Stalder, U., Bleiner, D., Kern, S., Bigler, L., Kohler, H.-P. E., & Heeb, N. V. (2025). The metabolome of Sphingobium chinhatense IP26 exposed to chlorinated paraffins : efficient data analysis with RASER. Chemosphere, 373(144160). https://doi.org/10.1016/j.chemosphere.2025.144160
• Hutter, J., Mendo Diaz, O., Knobloch, M. C., Zennegg, M., Vogel, J. C., Durisch, E., Stalder, U., Bigler, L., Kern, S., Buser, A. M., & Heeb, N. V. (2025). Temporal trends and spatial variations of chlorinated paraffins and olefins in sewage sludge from eight Swiss wastewater treatment plants from 1993 to 2020. Chemosphere, 372(144071). https://doi.org/10.1016/j.chemosphere.2025.144071
• Mendo Diaz, O., Patiny, L., Tell, A., Hutter, J., Knobloch, M., Stalder, U., Kern, S., Bigler, L., Heeb, N., & Bleiner, D. (2024). A quasi real-time evaluation of high-resolution mass spectra of complex chlorinated paraffin mixtures and their transformation products. Analytical Chemistry, 96(30), 12378–12386. https://doi.org/10.1021/acs.analchem.4c01723
• Knobloch, M. C., Hutter, J., Mendo Diaz, O., Zennegg, M., Vogel, J. C., Durisch, E., Stalder, U., Bigler, L., Kern, S., Bleiner, D., & Heeb, N. V. (2023). Evolution of chlorinated paraffin and olefin fingerprints in sewage sludge from 1993 to 2020 of a Swiss municipal wastewater treatment plant. Chemosphere, 349(140825). https://doi.org/10.1016/j.chemosphere.2023.140825
• Mendo Diaz, O., Tell, A., Knobloch, M., Canonica, E., Walder, C., Buser, A. M., Stalder, U., Bigler, L., Kern, S., Bleiner, D., & Heeb, N. V. (2023). Fingerprinting of chlorinated paraffins and their transformation products in plastic consumer products. Chemosphere, 338(139552). https://doi.org/10.1016/j.chemosphere.2023.139552
• Knobloch, M. C., Mathis, F., Mendo Diaz, O., Stalder, U., Bigler, L., Kern, S., Bleiner, D., & Heeb, N. V. (2022). Selective and fast analysis of chlorinated paraffins in the presence of chlorinated mono-, di-, and tri-olefins with the R-based automated spectra evaluation routine (RASER). Analytical Chemistry, 94, 13777–13784. https://doi.org/10.1021/acs.analchem.2c02240
• Knobloch, M. C., Schinkel, L., Kohler, H.-P. E., Mathis, F., Kern, S., Bleiner, D., & Heeb, N. V. (2021). Transformation of short-chain chlorinated paraffins and olefins with the bacterial dehalogenase LinB from Sphingobium Indicum : Kinetic models for the homologue-specific conversion of reactive and persistent material. Chemosphere, 283(131199). https://doi.org/10.1016/j.chemosphere.2021.131199
• Knobloch, M. C., Mathis, F., Fleischmann, T., Kohler, H.-P. E., Kern, S., Bleiner, D., & Heeb, N. V. (2021). Enzymatic synthesis and formation kinetics of mono- and di-hydroxylated chlorinated paraffins with the bacterial dehalogenase LinB from Sphingobium indicum. Chemosphere, 291, Part 2(132939). https://doi.org/10.1016/j.chemosphere.2021.132939
• Knobloch, M. C., Sprengel, J., Mathis, F., Haag, R., Kern, S., Bleiner, D., Vetter, W., & Heeb, N. V. (2021). Chemical synthesis and characterization of single-chain C18-chloroparaffin materials with defined degrees of chlorination. Chemosphere, 291, Part 2(132938). https://doi.org/10.1016/j.chemosphere.2021.132938
• Mainetti, T., Palmisano, M., Rezzonico, F., Stres, B., Kern, S., & Smits, T. H. M. (2021). Broad diversity of bacteria degrading 17ß-estradiol-3-sulfate isolated from river sediment and biofilm at a wastewater treatment plant discharge. Archives of Microbiology, 203(7), 4209–4219. https://doi.org/10.1007/s00203-021-02409-0
• Berchtold, C., Bourgeois, J.-P., Christen, V., Dabros, M., Demuth, C., Hoffmann, A., Kalman, F., Kern, S., Marcon, N., Nicolet, O., Pfeifer, M. E., Piantini, U., Prim, D., Portmann, C., Roth, S., Segura, J.-M., Vorlet, O., Yeretzian, C., Zollinger, M., & Schlotterbeck, G. (2020). Analytical platforms at Swiss universities of applied sciences. Chimia, 74(7-8), 618–628. https://doi.org/10.2533/chimia.2020.618
• Natsch, A., Kern, S., Corbi, E., Pérès, C., Nägelin, M., Leijs, H., von Strien, M., Calandra, M. J., & Wang, Y. (2018). Interlaboratory evaluation of methods to quantify skin-sensitizing hydroperoxides of limonene and linalool (II) : analysis in cosmetic bases. Flavour and Fragrance Journal, 33(4), 322–330. https://doi.org/10.1002/ffj.3451
• Laue, H., Kern, S., Badertscher, R. P., Ellis, G., & Natsch, A. (2017). p-alkyl-benzoyl-CoA conjugates as relevant metabolites of aromatic aldehydes with rat testicular toxicity-studies leading to the design of a safer new fragrance chemical. Toxicological Sciences, 160(2), 244–255. https://doi.org/10.1093/toxsci/kfx178
• Natsch, A., Emter, R., Badertscher, R. P., Brunner, G., Granier, T., Kern, S., & Ellis, G. (2015). Oxidative tryptophan modification by terpene- and squalene-hydroperoxides and a possible link to cross-reactions in diagnostic tests. Chemical Research in Toxicology, 28(6), 1205–1208. https://doi.org/10.1021/acs.chemrestox.5b00039
• Kern, S., Dkhil, H., Hendarsa, P., Ellis, G., & Natsch, A. (2014). Detection of potentially skin sensitizing hydroperoxides of linalool in fragranced products. Analytical and Bioanalytical Chemistry, 406(25), 6165–6178. https://doi.org/10.1007/s00216-014-8066-3
• Laue, H., Gfeller, H., Jenner, K. J., Nichols, J. W., Kern, S., & Natsch, A. (2014). Predicting the bioconcentration of fragrance ingredients by rainbow trout using measured rates of in vitro intrinsic clearance. Environmental Science & Technology, 48(16), 9486–9495. https://doi.org/10.1021/es500904h
• Kern, S., Granier, T., Dkhil, H., Haupt, T., Ellis, G., & Natsch, A. (2014). Stability of limonene and monitoring of a hydroperoxide in fragranced products. Flavour and Fragrance Journal, 29(5), 277–286. https://doi.org/10.1002/ffj.3210
• Kern, S., Singer, H., Hollender, J., Schwarzenbach, R. P., & Fenner, K. (2011). Assessing exposure to transformation products of soil-applied organic contaminants in surface water : comparison of model predictions and field data. Environmental Science & Technology, 45(7), 2833–2841. https://doi.org/10.1021/es102537b
• Kern, S., Baumgartner, R., Helbling, D. E., Hollender, J., Singer, H., Loos, M. J., Schwarzenbach, R. P., & Fenner, K. (2010). A tiered procedure for assessing the formation of biotransformation products of pharmaceuticals and biocides during activated sludge treatment. Journal of Environmental Monitoring, 12(11), 2100–2111. https://doi.org/10.1039/c0em00238k
• Kern, S., Fenner, K., Singer, H. P., Schwarzenbach, R. P., & Hollender, J. (2009). Identification of transformation products of organic contaminants in natural waters by computer-aided prediction and high-resolution mass spectrometry. Environmental Science & Technology, 43(18), 7039–7046. https://doi.org/10.1021/es901979h

Other publications

Knobloch, M. C., Hutter, J., Tell, A., Mendo Diaz, O., Mathis, F., Stalder, U., Bigler, L., Kern, S., Heeb, N. V., & Bleiner, D. (2023). RASER : a tool for rapid mass spectra analysis of chlorinated paraffins. Chimia, 77(1/2). https://doi.org/10.2533/chimia.2023.68

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