Extracellular vesicles for targeted delivery of new antimicrobials
Description
Infectious disease caused by bacteria constitutes a major threat to human health. Althoughantibiotics control bacterial infections, their efficacy is mitigated by the rise of antibioticresistance. Further challenging elimination of pathogenic bacteria, some species such asStaphylococcus aureus, responsible for a broad variety of infections, escape antibiotics bypersisting inside host cells. Here we will establish functionalized extracellular vesicles as anovel drug delivery system for target-specific, intracellular delivery of novel antimicrobialswith proven efficacy against S. aureus.
Key data
Projectlead
Deputy Projectlead
Project team
Prof. Martin Loessner, Prof. Daniel Razansky
Project partners
Eidgenössische Technische Hochschule Zürich ETH / Institut für Lebensmittelwissenschaften, Ernährung und Gesundheit; Institut für Biomedizinische Technik IBT (joint institution ETHZ, UZH)
Project status
completed, 04/2022 - 10/2023
Institute/Centre
Institute of Chemistry and Biotechnology (ICBT)
Funding partner
Innovationsprojekt