Morbillivirus cell entry machinery: mechanisms, structures and antiviral drug discovery

Projectlead

Prof. Dr. Dimitrios Fotiadis (Universität Bern)

Co-Projectlead

Prof. Dr. Rainer Riedl, Dr. Philippe Plattet (Universität Bern)

Project team

Flavio Gall, Dr. Dimanthi Pliatsika

Project partners

Universität Bern / Institut für Biochemie und Molekulare Medizin & Abteilung Neurologische Wissenschaften

Project status

completed, 04/2019 - 03/2025

Institute/Centre

Institute of Chemistry and Biotechnology (ICBT)

Funding partner

Sinergia

Project budget

2'000'000 CHF

Publications

Protection against lethal canine distemper virus infection by a dual epitope-targeting synthetic antibody

2026 Scherer, Melanie; Djabeur, Nadia; Siering, Oliver; Jeckelmann, Jean-Marc; Wyss, Marianne; Cresci, Marina; Di Palma Subran, Morgane; Riedl, Rainer; Chames, Patrick; Pfaller, Christian K.; Sawatsky, Bevan; Fotiadis, Dimitrios; Plattet, Philippe
Highly potent host-specific small-molecule inhibitor of paramyxovirus and pneumovirus replication with high resistance barrier

2021 Shrestha, Neeta; Gall, Flavio Max; Mathieu, Cyrille; Hierweger, Melanie Michaela; Brügger, Melanie; Alves, Marco P.; Vesin, Jonathan; Banfi, Damiano; Kalbermatter, David; Horvat, Branka; Chambon, Marc; Turcatti, Gerardo; Fotiadis, Dimitrios; Riedl, Rainer; Plattet, Philippe