Dr. Markus Rimann

Work at ZHAW

Position

• Group Leader 3D Tissues and Biofabrication
• Head of TEDD Competence Centre
• Lecturer in Biology
• Applied Research in Tissue Engineering

Focus

• Tissue Engineering
• Bioprinting
• Biofabrication
• Scaffold-free and scaffold-based 3D cell culture systems
• Automation of advanced cell culture systems
• Drug Development
• Regenerative Medicine

Teaching

• Cell Biology
• Micro Biology
• Cell and Tissue Therapy
• Practical Course in Cell Biology

Experience

• Group Leader and Lecturer
  ZHAW
  01 / 2011 - today
• Postdoc
  University of Zurich CABMM
  01 / 2010 - 12 / 2010
• Lab Technician in Biology
  ETH Zurich
  08 / 1999 - 08 / 2001

Education and Continuing education

Education

• PhD / Bioology and Materials
  ETH Zurich
  05 / 2006 - 12 / 2009
• MSc in Biology / Biotechnology
  ETH Zurich
  09 / 2001 - 08 / 2005
• Federal Certificate of Competence as Lab Technician in Biology (apprentice ship) / Biology
  ETH Zurich
  08 / 1996 - 07 / 1999

Continuing Education

CAS Didactics in Higher Education
PHZH
08 / 2020

Network

Membership of networks

• Dechema, member of the scientific committee of the 3D cell culture symposium
• Animalfree Research, Foundation Board Member
• EUROoCS, member of the European Organ-on-Chip Society
• biotechnet, Board Member
• TERMIS, member of the Tissue Engineering and Regenerative Medicine International Society
• IMPSS, International Microphysiological Systems Society

Social media

LinkedIn

Projects

• Production of Clean Meat using edible scaffolds / Project leader / Project ongoing
• Towards mechanically biocompatible implant materials for pelvic floor repair / Team member / Project ongoing
• 3D Gewebe TEDD / Project leader / Project ongoing
• Tumormikroumgebung 3D / Deputy project leader / Project completed
• Bioprinting of biofilms / Deputy project leader / Project completed
• Transglutaminase crosslinking potential / Deputy project leader / Project completed
• Bioprinting of vascular structures / Deputy project leader / Project completed

Publications

• D'Agostino, Stefania; Rimann, Markus; Gamba, Piergiorgio; Perilongo, Giorgio; Pozzobon, Michela; Raghunath, Michael,

  2022.

  Macromolecular crowding tuned extracellular matrix deposition in a bioprinted human rhabdomyosarcoma model.

  Bioprinting.

  27(e00213).

  Available from: https://doi.org/10.1016/j.bprint.2022.e00213

• Rimann, Markus; Jüngel, Astrid; Mousavi, Sara; Moeschlin, Nicole; Calcagni, Maurizio; Wuertz-Kozak, Karin; Brunner, Florian; Dudli, Stefan; Distler, Oliver; Adlhart, Christian,

  2022.

  Acrylonitrile and pullulan based nanofiber mats as easily accessible scaffolds for 3D skin cell models containing primary cells.

  Cells.

  11(3), pp. 445.

  Available from: https://doi.org/10.3390/cells11030445

• Alave Reyes-Furrer, Angela; De Andrade, Sonia; Bachmann, Dominic; Jeker, Heidi; Steinmann, Martin; Accart, Nathalie; Dunbar, Andrew; Rausch, Martin; Bono, Epifania; Rimann, Markus; Keller, Hansjörg,

  2021.

  Matrigel 3D bioprinting of contractile human skeletal muscle models recapitulating exercise and pharmacological responses.

  Communications Biology.

  4(1), pp. 1183.

  Available from: https://doi.org/10.1038/s42003-021-02691-0

• Kopanska, Katarzyna; Rimann, Markus,

  2020.

  Swiss-Chinese cooperation for organs-on-a-chip and stem cell research.

  ALTEX - Alternatives to Animal Experimentation.

  37(3).

  Available from: https://doi.org/10.14573/altex.2006161

• Kopanska, Katarzyna; Rimann, Markus,

  2020.

  TEDD Competence Centre Report 2019.

  Chimia.

  74(5), pp. 426-428.

  Available from: https://doi.org/10.2533/chimia.2020.426

• Kopanska, Katarzyna S.; Rimann, Markus; Laternser, Sandra; Raghunath, Michael,

  2019.

  Advanced in vitro models analysis.

  ALTEX - Alternatives to Animal Experimentation.

  36(1), pp. 144-147.

  Available from: https://doi.org/10.14573/altex.1812131

• Randall, Matthew J.; Jüngel, Astrid; Rimann, Markus; Wuertz-Kozak, Karin,

  2018.

  Advances in the biofabrication of 3D skin in vitro : healthy and pathological models.

  Frontiers in Bioengineering and Biotechnology.

  6(154), pp. 154.

  Available from: https://doi.org/10.3389/fbioe.2018.00154

• Laternser, Sandra; Keller, Hansjoerg; Leupin, Olivier; Rausch, Martin; Graf-Hausner, Ursula; Rimann, Markus,

  2018.

  A novel microplate 3D bioprinting platform for the engineering of muscle and tendon tissues.

  SLAS Technology: Translating Life Sciences Innovation.

  23(6), pp. 599-613.

  Available from: https://doi.org/10.1177/2472630318776594

• Raghunath, Michael; Rimann, Markus; Kopanska, Katarzyna S.; Laternser, Sandra,

  2018.

  TEDD annual meeting with 3D bioprinting workshop.

  Chimia.

  72(1/2), pp. 76-79.

  Available from: https://doi.org/10.2533/chimia.2018.76

• Rimann, Markus,

  2018.

  ZHAW Waedenswil : a new approach in the fight against cancer.

  Chimia.

  72(3), pp. 166-168.

  Available from: https://doi.org/10.2533/chimia.2018.166

• Rimann, Markus; Bono, Epifania; Annaheim, Helene; Bleisch, Matthias; Graf-Hausner, Ursula,

  2015.

  Standardized 3D bioprinting of soft tissue models with human primary cells.

  SLAS Technology: Translating Life Sciences Innovation.

  21(4), pp. 496-509.

  Available from: https://doi.org/10.1177/2211068214567146

• Fuchs, Bruno; Rimann, Markus; Graf-Hausner, Ursula; Laternser, Sandra; Kelm, Jens; Gvozdenovic, Ana; Muff, Roman,

  2014.

  An in vitro osteosarcoma 3D microtissue model for drug development.

  Journal of Biotechnology.

  189, pp. 129-135.

  Available from: https://doi.org/10.1016/j.jbiotec.2014.09.005

• Rimann, Markus; Graf-Hausner, Ursula; Patocchi-Tenzer, Isabel; Angres, Brigitte; Braum, Susanne,

  2014.

  Automation of 3D cell culture using chemically defined hydrogels.

  SLAS Technology: Translating Life Sciences Innovation.

  19(2), pp. 191-197.

  Available from: https://doi.org/10.1177/2211068213508651

• Rimann, Markus; Angres, Brigitte; Patocchi-Tenzer, Isabel; Braum, Susanne; Graf-Hausner, Ursula,

  2013.

  TEDD - innovation network for 3D cell cultivation : 3D cell culture for drug development.

  Chimia.

  67(11), pp. 822-824.

  Available from: https://doi.org/10.2533/chimia.2013.822

• Rimann, Markus; Graf-Hausner, Ursula,

  2012.

  Synthetic 3D multicellular systems for drug development.

  Current Opinion in Biotechnology.

  23(5), pp. 803-809.

  Available from: https://doi.org/10.1016/j.copbio.2012.01.011

• Rimann, Markus; Graf-Hausner, Ursula; Müller, Michael,

  2017.

  Bioresorbable polymers for bioprinting applications

  .

  In:

  Perale, Giuseppe; Hilborn, Jöns, eds.,

  Bioresorbable polymers for biomedical applications : from fundamentals to translational medicine.

  Amsterdam:

  Elsevier.

  pp. 331-362.

  Woodhead Publishing series in biomaterials ; 120.

  Available from: https://doi.org/10.1016/B978-0-08-100262-9.00015-X

• Bono, Epifania; Sheard, Jonathan; Mikkonen, Piia; Rimann, Markus,

  2022.

  Automation of 3D cell culture using cellulose-based scaffolds [poster].

  In:

  Biointerfaces International Conference (BIC), Zurich, Switzerland, 12-15 September 2022.

  Winterthur:

  ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

  Available from: https://doi.org/10.21256/zhaw-25998

• Kopanska, Katarzyna S; Rimann, Markus,

  2022.

  Cross-industrial applications of organotypic models.

  ALTEX - Alternatives to Animal Experimentation.

  39(1), pp. 155-158.

  Available from: https://doi.org/10.14573/altex.2112202

• Kopanska, Katarzyna S.; Rimann, Markus,

  2021.

  TEDD annual meeting 2020 : 10th anniversary, 10 years of innovation in tissue engineering.

  ALTEX - Alternatives to Animal Experimentation.

  38(1), pp. 166-167.

  Available from: https://doi.org/10.14573/altex.2012151

• Bono, Epifania; Evers, Christoph; Schmid, Franca; Graf-Hausner, Ursula; Rimann, Markus,

  2017.

  In vitro characterization of a new composite material for biomedical applications and 3D (bio)printing [poster].

  In:

  TEDD Annual Meeting, Wädenswil, 8-9 November 2017.

  ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

  Available from: https://doi.org/10.21256/zhaw-3587

• Rimann, Markus; Bono, Epifania; Picenoni, Armin; Felley-Bosco, Emanuela; Meyer, Andreas; Pelleaux, René; Hund, Corinna,

  2017.

  Development of a matrix-based technology platform for the high throughput analysis of 3D cell cultures [poster].

  In:

  Swiss Medtech Day, Bern, 13 June 2017.

  ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

  Available from: https://doi.org/10.21256/zhaw-3588

• Bono, Epifania; Mathes, Stephanie; Rimann, Markus,

  2017.

  Evaluation of 3D hepatic tissue models for bioprinting [poster].

  In:

  TERMIS-EU 2017 Conference, Davos, 26-30 June 2017.

  ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

  Available from: https://doi.org/10.21256/zhaw-3590

• Rimann, Markus; Laternser, Sandra; Bono, Epifania; Bleisch, Matthias; Eggmann, Kurt; Quidiello, Daniel; Fässler, Thomas; Keller, Hansjörg; Leupin, Olivier; Rausch, Martin; Hartmann, Lilian; Alave-Reyes, Angela; Thurner, Marc; Scheidegger, Andreas; Graf-Hausner, Ursula,

  2016.

  A novel multiwell device for drug development with bioprinted 3D human tendon and skeletal muscle tissues [poster].

  In:

  Swiss Medtech Day, Bern, 7 June 2016.

• Rimann, Markus; Graf-Hausner, Ursula; Nosswitz, Michael; Wagner, Carsten; Morel, Alexandre,

  2016.

  Bioprinted kidney model for nephrotoxicity assessment [poster].

  In:

  Swiss Medtech Day, Bern, 7 June 2016.

• Rimann, Markus; Mathes, Stephanie; Raghunath, Michael; Rohrer, Jack,

  2016.

  Zurich university of applied sciences : center for cell biology and tissue engineering [poster].

  In:

  Roche Symposium, Basel, 2016.

• Raghunath, Michael; Rimann, Markus; Mathes, Stephanie; Rohrer, Jack,

  2016.

  Zurich University of Applied Sciences : center for cell biology and tissue engineering [poster].

  In:

  Roche Symposium, Basel, 2016.

• Graf-Hausner, Ursula; Rimann, Markus; Bono, Epifania; Laternser, Sandra; Bleisch, Matthias; Eggmann, Kurt; Quidiello, Daniel; Fässler, Thomas; Keller, Hansjörg; Leupin, Olivier; Rausch, Martin; Richter, Jens; Alave, Angela; Thurner, Marc; Scheidegger, Andreas,

  2015.

  A novel multiwell device for drug development with bioprinted 3D human tendon and skeletal muscle tissues [poster].

  In:

  CTI Medtech Event, Bern, 8. September 2015.

• Rimann, Markus; Laternser, Sandra; Bono, Epifania; Keller, Hansjörg; Leupin, Olivier; Fässler, Thomas; Eggmann, Kurt; Thurner, Marc; Graf-Hausner, Ursula,

  2015.

  Bioprinted muscle/tendon for drug assessment [poster].

  In:

  NTN Swiss Biotech Innovation Day: The potential of industry-academia collaborations, Zug, 19 August 2015.

• Graf-Hausner, Ursula; Rimann, Markus; Bono, Epifania; Laternser, Sandra; Bleisch, Matthias; Eggmann, Kurt; Quidiello, Daniel; Munz, Peter; Hauer, Matthias; Keller, Hansjörg; Richter, Jens; Alave, Angela; Leupin, Olivier; Thurner, Marc; Scheidegger, Andreas,

  2014.

  A novel multiwell device for drug development with bioprinted 3D human tendon and skeletal muscle tissues [poster].

  In:

  CTI Medtech Event, Bern, 2. September 2014.

• Pörtner, Ralf; Wagner, Ilka; Atanasova, Tamara; Gautam, Richa; Gattlen, Jasmin; Rimann, Markus; Bono, Epifania; Graf-Hausner, Ursula; Marx, Uwe,

  2014.

  Aktuelle Trends bei der in vitro-Substanztestung in Deutschland und in der Schweiz.

  BIOspektrum.

  20(4), pp. 470-472.

  Available from: https://doi.org/10.1007/s12268-014-0466-6

• Bono, Epifania; Rimann, Markus; Annaheim, Helene; Bleisch, Matthias; Kuster, Michael; Thurner, Marc; Meier, Christoph; Bossen, Anke; Graf-Hausner, Ursula,

  2014.

  Skin bioprinting : an innovative approach to produce standardized skin models on demand [poster].

  In:

  Swiss Biotech Innovation Day 2014 «the Potential of Industry-Academia Collaborations», Basel, 28 August 2014.

• Rimann, Markus; Annaheim, Helene; Meier, Christoph; Bossen, Anke; Kuster, Michael; Scheidegger, Andreas; Thurner, Marc; Graf-Hausner, Ursula,

  2013.

  Skin bioprinting : an innovative approach to produce standardized skin models on demand [poster].

  In:

  CTI Medtech Event 2013, Bern, 27. August 2013.

• Rimann, Markus; Novak, Franziska; Fried, Nicole; Kelm, Jens M.; Graf-Hausner, Ursula,

  2012.

  Cryopreservation of spherical tumor microtissues [poster].

  In:

  3D Cell Culture 2012: Zurich, 14-16 March 2012.

• Rimann, Markus; Annaheim, Helene; Meier, Christoph; Bossen, Anke; Scheidegger, Andreas; Kuster, Michael; Thurner, Marc; Graf-Hausner, Ursula,

  2012.

  Skin bioprinting : an innovative approach to produce standardized skin models on demand [poster].

  In:

  CTI Medtech Event 2012, Luzern, 24. September 2012.

• Rimann, Markus; Bleisch, Matthias; Kuster, Michael; Thurner, Marc; Meier, Christoph; Bossen, Anke; Graf-Hausner, Ursula,

  2011.

  Organomimetic skin model production based on a novel bioprinting technology [poster].

  In:

  CTI Medtech Event 2011, Bern, 23. August 2011.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula; Raghunath, Michael,

  2017.

  3D bioprinted tissue models for substance testing.

  In:

  International Conference and Exhibition - Society for Laboratory Automation and Screening (SLAS 2017), Washington, USA, 4–8 February 2017.

• Bono, Epifania; Rimann, Markus; Annaheim, Helene; Bleisch, Matthias; Kuster, Michael; Thurner, Marc; Graf-Hausner, Ursula,

  2016.

  Standardized 3D bioprinting of skin models for drug development.

  In:

  4th International Cosmetic Innovation Days «Cosminnov», Orléans, France, 24-25 May 2016.

• Rimann, Markus; Laternser, Sandra; Bono, Epifania; Nosswitz, Michael; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula,

  2016.

  Bioprinted tissues for substance testing.

  In:

  3D Cell Culture 2016, Freiburg, Germany, 19-21 April 2016.

• Rimann, Markus; Mathes, Stephanie; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Graf-Hausner, Ursula,

  2016.

  3D models for compound testing.

  In:

  3rd 3D Models & Drug Screening Conference, Berlin, Germany, 11-12 May 2016.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula,

  2016.

  3D tissue models : new perspectives in medicine.

  In:

  2016 Conference and Exhibition for Cutting-Edge Medicine (CLINAM 9), Basel, 26-29 June 2016.

• Rimann, Markus,

  2016.

  3D tissues and biofabrication for therapy and industrial applications.

  In:

  Spiez Convergence, Spiez, 5-8 September 2016.

• Graf-Hausner, Ursula; Rimann, Markus; Laternser, Sandra; Bono, Epifania; Eggmann, Kurt; Quidiello, Daniel; Fässler, Thomas; Keller, Hansjörg; Leupin, Olivier; Rausch, Martin; Hartmann, Lilian; Alave-Reyes, Angela; Thurner, Marc; Scheidegger, Andreas,

  2016.

  A novel multiwell device for drug development with bioprinted 3D human tendon and skeletal muscle tissues.

  In:

  Swiss Medtech Day, Bern, 7 June 2016.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula,

  2016.

  Bioprinted tissue models for substance evalution.

  In:

  Basel Life Science Week 2016, Basel, 19-23 September 2016.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula; Raghunath, Michael,

  2016.

  Bioprinted tissues for substance evaluation.

  In:

  Biointerfaces International 2016 Conference, Zurich, 23-25 August 2016.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Keller, Hansjörg; Leupin, Olivier; Graf-Hausner, Ursula,

  2015.

  Bioprinted soft tissue models for compound testing.

  In:

  International Conference on Biofabrication (Biofabrication 2015), Utrecht, Netherlands, 7-9 November 2015.

• Rimann, Markus,

  2015.

  Bioprinting : break-out session.

  In:

  Expert Forum on 3D printing «Changing the World one Print at a Time» - Swiss Re, Rüschlikon, 30. September 2015.

• Rimann, Markus; Bono, Epifania; Laternser, Sandra; Nosswitz, Michael; Morel, Alexandre; Keller, Hansjörg; Leupin, Olivier; Wagner, Carsten; Graf-Hausner, Ursula,

  2015.

  Soft tissue bioprinting in tissue engineering for drug development.

  In:

  Olten Meeting 2015: Antibiotics and Bioprinting - for a better life, Biotechnet Switzerland, Olten, 18 November 2015.

• Rimann, Markus; Galea, Laetitia,

  2015.

  Tissue bioprinting for compound evaluation.

  In:

  CTI Medtech Event, Bern, 8. September 2015.

• Rimann, Markus,

  2014.

  Competence centre TEDD tissue engineering for drug development.

  In:

  15th Edition of the Swiss Soft Days (SSD), Lausanne, 2 October 2014.

• Rimann, Markus,

  2014.

  Additive Verfahren mit biologischen Materialien.

  In:

  3D Druck und Healthtech - Healthtech Cluster Switzerland, Schwyz, 28. August 2014.

• Rimann, Markus,

  2014.

  Bioprinting : aktueller Stand in der Forschung.

  In:

  3D Druck: Revolution in Technik, Recht und Medizin?, Winterthur, 27. August 2014.

• Bono, Epifania; Rimann, Markus; Annaheim, Helene; Bleisch, Matthias; Kuster, Michael; Thurner, Marc; Meier, Christoph; Bossen, Anke; Graf-Hausner, Ursula,

  2014.

  Skin bioprinting : an approach to produce standardized skin models on demand.

  In:

  DECHEMA - 3D Cell Culture 2014, Freiburg, Germany, 25-27 June 2014.

• Rimann, Markus,

  2014.

  3D cell-based assays for drug de-risking.

  In:

  SLAS Short course, Basel, September 2014.

• Rimann, Markus,

  2014.

  A 3D osteosarcoma model.

  In:

  Wissenschaftliches Forum über «Challenges and Opportunities in the Development of Novel Anti-Tumor Therapies», Schlieren, September 2014.

• Rimann, Markus,

  2014.

  Bioprinting von 3D Gewebemodellen.

  In:

  5. Kongress Industrielle Zelltechnik, Lübeck, Deutschland, 11.-12. September 2014.

• Fuchs, Bruno; Rimann, Markus; Graf-Hausner, Ursula; Laternser, Sandra; Gvozdenovic, Ana; Kelm, Jens M.; Muff, Roman,

  2014.

  Human 3D osteosarcoma models for drug testing.

  In:

  3D Cell Culture 2014, Freiburg, Germany, 25-27 June 2014.

• Rimann, Markus,

  2013.

  Automation of 3D cell cultures using defined biomimetic hydrogels.

  In:

  FAST Congress, Boston, USA, 17-19 October 2013.

• Rimann, Markus; Bleisch, Matthias; Kuster, Michael; Thurner, Marc; Meier, Christoph; Bossen, Anke; Graf-Hausner, Ursula,

  2012.

  Organomimetic skin model production based on a novel bioprinting technology.

  In:

  3D Cell Culture 2012: Zurich, 14-16 March 2012.

Other publications

PubMed

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