Intellishaker
Description
Integrated Bioprocess Development Solutions for Shaken Cultures: Eurostars-Project: E!11795. The consortium will develop a unique product that offers a cultivation success quarantee for shake flask cultivation to the user. The System consists of an Internet knowledge database for parallel bioprocess development in Pharmaceutical and technical applications, and is combined with advanced sensor technology and automated data analysis Software for cultivation monitoring. The product will complement existing flask Shakers, is flexible, scalable and connected using wireless Technology.
Key Data
Projectlead
Prof. Dr. Dieter Eibl, Dr. Gernot John
Deputy Projectlead
Prof. Christoph Herwig, Rüdiger Maschke
Project team
Sandra Steiner
Project partners
PreSens Precision Sensing GmbH; Körber AG / Pharma
Project status
completed, 05/2018 - 04/2021
Funding partner
Eurostars / Projekt Nr. E!11795; Staatssekretariat für Bildung, Forschung und Innovation SBFI
Project budget
246'000 CHF
Publications
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Automated cell line characterization in shake flasks for multiple organisms
2022 Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Herwig, Christoph; Eibl, Dieter
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Improved time resolved KPI and strain characterization of multiple hosts in shake flasks using advanced online analytics and data science
2022 Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Herwig, Christoph; Eibl, Dieter
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Monitoring of oxygen, pH, CO2, and biomass in smart single‐use shake flasks
2022 Maschke, Rüdiger; John, Gernot T.; Eibl, Dieter
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Predictive monitoring of shake flask cultures with online estimated growth models
2021 Pretzner, Barbara; Maschke, Rüdiger; Haiderer, Claudia; John, Gernot T.; Herwig, Christoph; Sykacek, Peter
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Interpreting SFR vario online data gathered in plant cell suspension culture : characterization of plant cell lines for successful production processes
2020 Maschke, Rüdiger; Pretzner, Barbara; John, Gernot; Eibl, Dieter
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Characterizing CHO cell lines with SFR vario : what online measured data can tell about your cell culture
2020 Maschke, Rüdiger; Pretzner, Barbara; John, Gernot T.; Eibl, Dieter
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Using online biomass and OUR measurements to characterize microbials, plant and animal cells growth in shake flasks
2020 Maschke, Rüdiger; John, Gernot T.