Dr. Sabina Gerber

Management role

Head, Bioanalytics Group

Position at the ZHAW

Lecturer in Bioanalytics

https://www.zhaw.ch/icbt/biochemie

Publications before appointment at the ZHAW

Structure and mechanism of an active lipid-linked oligosaccharide flippase
Perez C, Gerber S, Boilevin J, Bucher M, Darbre T, Aebi M, Reymond JL, Locher KP
Nature. 2015 Aug 27;524(7566):433-8


On the efficiency of NHS ester cross-linkers for stabilizing integral membrane protein complexes
Chen F, Gerber S, Korkhov VM, Mireku S, Bucher M, Locher KP, Zenobi R
J Am Soc Mass Spectrom. 2015 Mar;26(3):493-8


Antibodies to Staphylococcus aureus serotype 8 capsular polysaccharide react with and protect against serotype 5 and 8 isolates
Park S, Gerber S, Lee JC
Infect Immun. 2014 Dec;82(12):5049-55


A catalytically essential motif in external loop 5 of the bacterial oligosaccharyltransferase PglB
Lizak C*, Gerber S*, Zinne D, Michaud G, Schubert M, Chen F, Bucher M, Darbre T, Zenobi R, Reymond JL, Locher KP
J Biol Chem. 2014 Jan 10;289(2):735-46
*equal contribution


Unexpected reactivity and mechanism of carboxamide activation in bacterial N-linked protein glycosylation
Lizak C*, Gerber S*, Michaud G, Schubert M, Fan YY, Bucher M, Darbre T, Aebi M, Reymond JL, Locher KP
Nat Commun. 2013;4:2627
*equal contribution


High-mass matrix-assisted laser desorption ionization-mass spectrometry of integral membrane proteins and their complexes
Chen F, Gerber S, Heuser K, Korkhov VM, Lizak C, Mireku S, Locher KP, Zenobi R
Anal Chem. 2013 Apr 2;85(7):3483-8


Mechanism of bacterial oligosaccharyltransferase: in vitro quantification of sequon binding and catalysis
Gerber S*, Lizak C*, Michaud G, Bucher M, Darbre T, Aebi M, Reymond JL, Locher KP
J Biol Chem. 2013 Mar 29;288(13):8849-61
*equal contribution


X-ray structure of a bacterial oligosaccharyltransferase
Lizak C, Gerber S, Numao S, Aebi M, Locher KP
Nature. 2011 Jun 15;474(7351):350-5


Structural basis of trans-inhibition in a molybdate/tungstate ABC Transporter
Gerber S, Comellas-Bigler M, Goetz BA, Locher KP
Science. 2008 Jul 11;321(5886):246-50


Synthesis and testing of a focused phenothiazine library for binding to HIV-1 TAR RNA
Mayer M, Lang PT, Gerber S, Madrid PB, Pinto IG, Guy RK, James TL
Chem Biol. 2006 Sep;13(9):993-1000

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