Dr. Manuel Gil

Dr. Manuel Gil

Dr. Manuel Gil
ZHAW Life Sciences und Facility Management

+41 (0) 58 934 57 44

Persönliches Profil


  • Studiengangleitung MSc Vertiefung in Applied Computational Life Sciences

Tätigkeit an der ZHAW als

Senior researcher and lecturer
Program director MSc specialisation in Applied Computational Life Sciences


Arbeits- und Forschungsschwerpunkte, Spezialkenntnisse

Algorithms, Inferential Statistics, Computational Science, Computational Genomics, Stochastic Modeling for Genomic Data, Computational Linguistics

Aus- und Fortbildung

Dr. sc. ETH

Beruflicher Werdegang

2013—2015 Senior Postdoc, Prof. C. v. Mering’s group, Institute of Molecular Life Sciences, Uni Zurich
2012—2013 Visiting Scientist, Prof. A. v. Haeseler’s group, Center for Integrative Bioinformatics, Vienna
2011—2012 Lecturer, ETH Zurich
2010—2012 Postdoc, Prof. G. Gonnet’s group, ETH Zurich

Mitglied in Netzwerken


Beiträge, peer-reviewed

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The SIB Swiss Institute of Bioinformatics’ resources: focus on curated databases


In: Nucleic Acids Research. (doi: 10.1093/nar/gkv1310). Oxford: Oxford University Press. Peer reviewed.

Beiträge, nicht peer-reviewed

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Current methods for automated filtering of multiple sequence alignments frequently worsen single-gene phylogenetic inference


Systematic biology, 64, 5. 778/791.

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Methodologies for phylogenetic inference


In: Encyclopedia of Life Sciences . Hoboken, New Jersey, United States: John Wiley & Sons.

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Simple chained guide trees give poorer multiple sequence alignments than inferred trees in simulation and phylogenetic benchmarks


Proceedings of the National Academy of Sciences, 112, 2. E99/E100.

Publikationen vor Tätigkeit an der ZHAW

Gil M (2014) Fast and accurate estimation of the covariance between pairwise maximum likelihood distances, PeerJ, 2:e583

Gil M*, Zanetti MS*, Zoller S, Anisimova M (2013) CodonPhyML: Fast maximum likelihood phylogeny estimation under codon substitution models, Mol. Biol. Evol., 30(6):1270–80

Altenhoff A, Gil M, Gonnet GH, Dessimoz C (2013) Inferring hierarchical orthologous groups from orthologous gene pairs, PLoS ONE, 8(1):e53786

Anisimova M, Gil M, Dufayard JF, Dessimoz C, Gascuel O (2011) Survey of branch support methods demonstrates accuracy, power, and robustness of fast likelihood-based approximation schemes, Systematic Biology, 60(5):685–699

Dessimoz C*, Gil M* (2010) Phylogenetic assessment of alignments reveals neglected tree signal in gaps, Genome Biology, 11:R37

Dessimoz C*, Gil M* (2008) Covariance of maximum likelihood evolutionary distances between sequences aligned pairwise, BMC Evol Biol, 8:179

Fultona DC, Stettler M, Mettler T, Vaughan CK, Li J, Francisco P, Gil M, Reinhold H, Eicke S, Messerli G, Dorkin G, Halliday K, Smith AM, Smith SM, Zeeman SC, BETA-AMYLASE 4 (2008) A Noncatalytic protein that is required for starch breakdown, acts upstream of three active Beta-amylases in Arabidopsis chloroplasts, Plant Cell, 20:1040–1058

Dessimoz C, Gil M, Schneider A, Gonnet GH (2006) Fast estimation of the difference of PAM/JTT evolutionary distances in triplets of homologous sequences, BMC Bioinformatics, 7:529

Gil M, Gonnet GH, Petersen W (2006) A repetition test for random number generators, Monte Carlo Meth Appl, 12(5):385–393

Gil M, Dessimoz C, Gonnet GH (2005) A dimensionless fit measure for phylogenetic distance trees, J Bioinform Comput Biol, 3(6):1429–1440

Dessimoz C, Cannarozzi G, Gil M, Margadant M, Roth A, Schneider A, Gonnet GH, (2005) OMA, a comprehensive, automated project for the identification of orthologs from complete genome data: introduction and first achievements, RECOMB 2005, LNBI 3687:61–72

Hofstoetter C, Gil M, Eng K, Indiveri G, Mintz M, Kramer J, Verschure PFMJ (2005) The Cerebellum Chip: an analog VLSI implementation of a cerebellar model of classical conditioning, NIPS, 17:577–584

Iantorno S, Gori K, Goldman N, Gil M, Dessimoz C (2014) Who watches the watchmen? An appraisal of benchmarks for multiple sequence alignment, in: Multiple Sequence Alignment Methods (Editor: Russell D), Methods in Molecular Biology, Springer Humana, Vol 1079: 59–73

Gil M, Gonnet GH (2009) Phylogenetic tree building methods, in: Bioinformatics - A Swiss Perspective (Editors:Appel R, Feytmans E, Swiss Institute of Bioinformatics, Lausanne), World Scientific