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Prof. Dr. Steffi Lehmann

Prof. Dr. Steffi Lehmann

Prof. Dr. Steffi Lehmann

ZHAW School of Life Sciences and Facility Management
Section for Pharmaceutical Technology and Pharmacology
Einsiedlerstrasse 31
8820 Wädenswil

+41 (0) 58 934 50 64
steffi.lehmann@zhaw.ch

Personal profile

Position at the ZHAW

https//www.zhaw.ch/de/lsfm/institute-zentren/icbt/pharmazeutische-wirkstoffforschung-und-arzneimittelentwicklung/pharmazeutische-technologie-und-pharmakologie/

Projects

Publications before appointment at the ZHAW

Lehmann S, Te Boekhorst V, Odenthal J, Bianchi R, van Helvert S, Ikenberg K, Ilina O, Stoma S, Xandry J, Jiang L, Grenman R, Rudin M, Friedl P. Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells. Current biology : CB. 2017;27:392-400.

Herter S, Morra L, Schlenker R, Sulcova J, Fahrni L, Waldhauer I, Lehmann S, Reislander T, Agarkova I, Kelm JM, Klein C, Umana P, and Bacac M. A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents. Cancer immunology, immunotherapy : CII. 2017;66:129-40.

Lehmann S, Perera R, Grimm HP, Sam J, Colombetti S, Fauti T, Schaller T, Freimoser-Grundschober A, Zielonka J, Stoma S, Rudin M, Klein C, Umana P, Gerdes C, Bacac M. In vivo imaging of the activity of CEA TCB, a novel T-cell bispecific antibody, reveals specific tumor targeting and fast induction of T-cell mediated tumor killing. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016; 22(17):4417-27.

Commented by: Teijeira A, Etxeberria I, Ponz-Sarvise M, Melero I. Immunotherapy of Cancer Visualized by Live Microscopy: Seeing Is Believing. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016;22:4277-9.

Bacac M, Fauti T, Sam J, Colombetti S, Weinzierl T, Ouaret D, Bodmer W, Lehmann S, Hofer T, Hosse R, Moessner E, Ast O, Bruenker P, Grau-Richards S, Schaller T, Seidl A, Gerdes C, Perro M, Nicolini V, Steinhoff N, Dudal S, Neumann S, Hirschheydt T, Jaeger C, Saro J, Karanikas V, Klein C, Umana P. A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016; 22(13):3286-97.

Terry SY, Boerman OC, Gerrits D, Franssen GM, Metselaar JM, Lehmann S, et al. 11In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages. European journal of nuclear medicine and molecular imaging. 2015;42:1430-8.

Nagelkerke A, Bussink J, Mujcic H, Wouters BG, Lehmann S, Sweep FC, et al. Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response. Breast cancer research : BCR. 2013;15:R2.

Dominietto M, Lehmann S, Keist R, Rudin M. Pattern analysis accounts for heterogeneity observed in MRI studies of tumor angiogenesis. Magnetic resonance in medicine. 2013;70:1481-90.

Lehmann S, Garayoa EG, Blanc A, Keist R, Schibli R, Rudin M. Recording intracellular molecular events from the outside: glycosylphosphatidylinositol-anchored avidin as a reporter protein for in vivo imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2011;52:445-52.

Lehmann S, Stiehl DP, Honer M, Dominietto M, Keist R, Kotevic I, et al. Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events. Proceedings of the National Academy of Sciences of the United States of America. 2009;106:14004-9.