Prof. Dr. Steffi Lehmann
Prof. Dr. Steffi Lehmann
ZHAW
School of Life Sciences and Facility Management
Section for Pharmaceutical Technology and Pharmacology
Einsiedlerstrasse 31
8820 Wädenswil
Personal profile
Position at the ZHAW
Projects
- Novel phage derived antimicrobials / Project leader / Project ongoing
- Aroma beladene mesoporöse Silicapartikel (MSP) für Dropz / Project leader / Project ongoing
- Extracellular vesicles for targeted delivery of new antimicrobials / Project leader / Project ongoing
- Active modified surfaces for contained drug release / Project leader / Project completed
- Infused Drinking Water from Dropz / Deputy project leader / Project completed
- Development of novel tablet formulations for the detection of pathogenic bacteria / Project leader / Project completed
- Molekulare Analyse von CD30+ Lymphoma / Project leader / Project completed
- Modulatoren der MMP-Hemopexin-Domäne / Project co-leader / Project completed
- Preventing capsular contracture by coating of silicone implants with bioglass / Project leader / Project completed
Publications
-
Sabani, Besmira; Brand, Michael; Albert, Ina; Inderbitzin, Joelle; Eichenseher, Fritz; Schmelcher, Mathias; Rohrer, Jack; Riedl, Rainer; Lehmann, Steffi,
2023.
Nanomedicine: Nanotechnology, Biology and Medicine.
47(102607).
Available from: https://doi.org/10.1016/j.nano.2022.102607
Publications before appointment at the ZHAW
Lehmann S, Te Boekhorst V, Odenthal J, Bianchi R, van Helvert S, Ikenberg K, Ilina O, Stoma S, Xandry J, Jiang L, Grenman R, Rudin M, Friedl P. Hypoxia Induces a HIF-1-Dependent Transition from Collective-to-Amoeboid Dissemination in Epithelial Cancer Cells. Current biology : CB. 2017;27:392-400.
Herter S, Morra L, Schlenker R, Sulcova J, Fahrni L, Waldhauer I, Lehmann S, Reislander T, Agarkova I, Kelm JM, Klein C, Umana P, and Bacac M. A novel three-dimensional heterotypic spheroid model for the assessment of the activity of cancer immunotherapy agents. Cancer immunology, immunotherapy : CII. 2017;66:129-40.
Lehmann S, Perera R, Grimm HP, Sam J, Colombetti S, Fauti T, Schaller T, Freimoser-Grundschober A, Zielonka J, Stoma S, Rudin M, Klein C, Umana P, Gerdes C, Bacac M. In vivo imaging of the activity of CEA TCB, a novel T-cell bispecific antibody, reveals specific tumor targeting and fast induction of T-cell mediated tumor killing. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016; 22(17):4417-27.
Commented by: Teijeira A, Etxeberria I, Ponz-Sarvise M, Melero I. Immunotherapy of Cancer Visualized by Live Microscopy: Seeing Is Believing. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016;22:4277-9.
Bacac M, Fauti T, Sam J, Colombetti S, Weinzierl T, Ouaret D, Bodmer W, Lehmann S, Hofer T, Hosse R, Moessner E, Ast O, Bruenker P, Grau-Richards S, Schaller T, Seidl A, Gerdes C, Perro M, Nicolini V, Steinhoff N, Dudal S, Neumann S, Hirschheydt T, Jaeger C, Saro J, Karanikas V, Klein C, Umana P. A Novel Carcinoembryonic Antigen T-Cell Bispecific Antibody (CEA TCB) for the Treatment of Solid Tumors. Clinical cancer research : an official journal of the American Association for Cancer Research. 2016; 22(13):3286-97.
Terry SY, Boerman OC, Gerrits D, Franssen GM, Metselaar JM, Lehmann S, et al. 11In-anti-F4/80-A3-1 antibody: a novel tracer to image macrophages. European journal of nuclear medicine and molecular imaging. 2015;42:1430-8.
Nagelkerke A, Bussink J, Mujcic H, Wouters BG, Lehmann S, Sweep FC, et al. Hypoxia stimulates migration of breast cancer cells via the PERK/ATF4/LAMP3-arm of the unfolded protein response. Breast cancer research : BCR. 2013;15:R2.
Dominietto M, Lehmann S, Keist R, Rudin M. Pattern analysis accounts for heterogeneity observed in MRI studies of tumor angiogenesis. Magnetic resonance in medicine. 2013;70:1481-90.
Lehmann S, Garayoa EG, Blanc A, Keist R, Schibli R, Rudin M. Recording intracellular molecular events from the outside: glycosylphosphatidylinositol-anchored avidin as a reporter protein for in vivo imaging. Journal of nuclear medicine : official publication, Society of Nuclear Medicine. 2011;52:445-52.
Lehmann S, Stiehl DP, Honer M, Dominietto M, Keist R, Kotevic I, et al. Longitudinal and multimodal in vivo imaging of tumor hypoxia and its downstream molecular events. Proceedings of the National Academy of Sciences of the United States of America. 2009;106:14004-9.