An Enzymatic Strategy for the Asymmetric Synthesis of Ionones by Engineered Squalene-Hopene Cyclases published in “Angewandte Chemie”
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monocyclic product (R)-γ-dihydroionone (1). By means of directed evolution, the production of production of (1) could be significantly improved. By analyses of the pure, geometric isomers nerylacetone (Z) and
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