Towards tailored mechanical properties of artificial tissue models

From histology to the physical skin model system to the computational model: The artificial skin model consists in an elastomeric matrix structured by a periodic pattern of liquid inclusions (top: prototype by ICP).

At a glance

Project leader : Dr. Barbara Röhrnbauer
Project team : Eléonore Cauquil, Luca Kiener, Dr. Fabrizio Spano
Project budget : CHF 48'000
Project status : completed
Funding partner : Internal
Contact person : Barbara Röhrnbauer

Description

The human skin is the interface between the environment and the body. The skin has several functions such as the thermoregulation, the protection from mechanical injuries, acting as a barrier against microorganisms and the tactile perception. In this project, we aim at developing an innovative artificial skin model based on the water content of the different layers of the human skin and at investigating how the water content influences its mechanical properties. Ultimately, a correlation shall allow to specifically tailor the mechanical properties of the model system to closely mimic skin.

Publications

Cauquil, Eléonore; Kiener, Luca; Hofmann, Jonas; Spano, Fabrizio; Röhrnbauer, Barbara,

2023.

A combined experimental and numerical method for tailoring the multi-scale mechanical properties of soft solid liquid composites [poster].

In:

33rd Annual Conference of the European Society for Biomaterials (ESB), Davos, Switzerland, 4-8 September 2023.

ZHAW Zürcher Hochschule für Angewandte Wissenschaften.

Available from: https://doi.org/10.21256/zhaw-30272

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