A cocktail of two bacteriophages is required to control Salmonella in vitro
Fieseler, Lars; (2014). A cocktail of two bacteriophages is required to control Salmonella in vitro: Posterpräsentation. In: Viruses of microbes: Structure and function, from molecules to communities (EMBO event 2014). EMBO conference series. Zürich: ETH Zürich.
Salmonella spp. can cause severe diarrhea in humans after consumption of contaminated food. Because bacteriophages are powerful agents for the control of food borne pathogens, several phages were isolated and characterized. Here we present an initial characterization of Salmonella phage isolates. Moreover, bacteriophages were applied to reduce viable cell counts of Salmonella in vitro. The data indicate that Salmonella can be efficiently eliminated by the application of phage cocktails containing a minimum of two phage isolates, while treatment of the bacteria with only a single phage isolate often resulted in regrowth of the treated culture.