CHIMIA article on “Innovation in Biocatalysis – A Swiss Network Project Coordinated by the Competence Center for Biocatalysis (CCBIO)”
The Competence Center for Biocatalysis (CCBIO) at the ZHAW promotes biocatalysis as a complementary method to classic organic synthesis and aims to help bridge the gap between academic laboratories and the production plant. By connecting relevant research competences CCBIO strives to develop a comprehensive biocatalytic toolbox consisting of enzyme libraries and methods, which will facilitate the development of biocatalytic and biosynthetic processes for the chemical and pharmaceutical industry.
Biocatalysis enables the sustainable production of chiral and highly functionalized compounds for the chemical and pharmaceutical industry. Recent key advances in DNA sequencing, gene synthesis and data analysis are now enabling scientists to tailor biocatalyst according to industrial needs and to reorganize enzymes into new biosynthetic pathways. This progress fuels the so-called «third wave of biocatalysis»1 and promises to unlock hitherto inaccessible enzyme activities for industrial biocatalysis and engineer microbial and fungal strains for the production of novel asset molecules.
1 U. T. Bornscheuer, et al. (2012) Nature 485, 185-194
CCBIO leads the network project «Innovation in Biocatalysis: A toolbox for sustainable bio-based production».
The program is supported by project contributions from the Swiss Higher Education Council. In case of two calls - «Research Projects» and «Curricular Elements» -projects have been selected for funding. A third call «Sustainability» will open in Spring 2019.